Nucleotide Transport and Metabolism

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase	F	Contig1	OEOE0785	COG0737	176	4e-45
Adenine deaminase	F	Contig1	OEOE0158	COG1001	530	1.0e-151
Adenine deaminase	F	Contig1	OEOE0259	COG1001	49	9e-07
Adenine deaminase	F	Contig1	OEOE1462	COG1001	413	1.0e-116
Adenine deaminase	F	Contig1	OEOE1728	COG1001	38	0.001
Adenosine deaminase	F	Contig1	OEOE0100	COG2169	58	5e-10
Adenosine deaminase	F	Contig1	OEOE0209	COG2169	63	2e-11
Adenosine deaminase	F	Contig1	OEOE0754	COG2169	49	6e-07
Adenosine deaminase	F	Contig1	OEOE1455	COG2169	59	6e-10
Adenosine deaminase	F	Contig1	OEOE1507	COG2169	59	4e-10
Adenosine deaminase	F	Contig1	OEOE1572	COG2169	54	2e-08
Adenosine deaminase	F	Contig1	OEOE1575	COG2169	63	4e-11
ADP-ribose pyrophosphatase	F	Contig1	OEOE0317	COG1051	58	4e-10
ADP-ribose pyrophosphatase	F	Contig1	OEOE0515	COG1051	79	2e-16
ADP-ribose pyrophosphatase	F	Contig1	OEOE0519	COG1051	70	1e-13
ADP-ribose pyrophosphatase	F	Contig1	OEOE0674	COG1051	33	0.008
ADP-ribose pyrophosphatase	F	Contig1	OEOE1181	COG1051	70	9e-14
ADP-ribose pyrophosphatase	F	Contig1	OEOE1697	COG1051	41	7e-05
Cytosine/adenosine deaminase	F	Contig1	OEOE1303	COG0590	111	2e-26
Cytosine/adenosine deaminase	F	Contig1	OEOE1413	COG0590	174	3e-45
Cytosine/uracil/thiamine/allantoin permease	F	Contig1	OEOE1469	COG1953	63	5e-11
Deoxycytidylate deaminase	F	Contig1	OEOE1303	COG2131	44	6e-06
Deoxycytidylate deaminase	F	Contig1	OEOE1413	COG2131	48	2e-07
Deoxynucleoside kinase	F	Contig1	OEOE0437	COG1428	208	3e-55
Deoxynucleoside kinase	F	Contig1	OEOE0849	COG1428	202	2e-53
Deoxyribose-phosphate aldolase	F	Contig1	OEOE1206	COG0274	156	6e-40
dGTP triphosphohydrolase	F	Contig1	OEOE1790	COG0232	41	2e-04
Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase	F	Contig1	OEOE0929	COG0537	116	4e-28
Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase	F	Contig1	OEOE1275	COG0537	130	4e-32
Exopolyphosphatase	F	Contig1	OEOE1628	COG0248	234	5e-63
Formyltetrahydrofolate synthetase	F	Contig1	OEOE0769	COG2759	741	0.0
Guanylate kinase	F	Contig1	OEOE1231	COG0194	233	7e-63
Guanylate kinase	F	Contig1	OEOE1432	COG0194	103	1e-23
Guanylate kinase	F	Contig1	OEOE1689	COG0194	35	0.004
Inosine-uridine nucleoside N-ribohydrolase	F	Contig1	OEOE0154	COG1957	262	2e-71
Inosine-uridine nucleoside N-ribohydrolase	F	Contig1	OEOE1461	COG1957	245	3e-66
Inosine-uridine nucleoside N-ribohydrolase	F	Contig1	OEOE1673	COG1957	181	7e-47
Nucleoside 2-deoxyribosyltransferase	F	Contig1	OEOE0891	COG3613	61	4e-11
Nucleoside 2-deoxyribosyltransferase	F	Contig1	OEOE0969	COG3613	80	8e-17
Nucleoside permease	F	Contig1	OEOE0820	COG1972	330	1e-91
Orotate phosphoribosyltransferase homologs	F	Contig1	OEOE0160	COG0856	38	7e-04
Orotate phosphoribosyltransferase homologs	F	Contig1	OEOE0263	COG0856	55	5e-09
Orotate phosphoribosyltransferase homologs	F	Contig1	OEOE0537	COG0856	36	0.002
Orotate phosphoribosyltransferase homologs	F	Contig1	OEOE1069	COG0856	50	1e-07
Orotate phosphoribosyltransferase homologs	F	Contig1	OEOE1124	COG0856	36	0.002
Orotate phosphoribosyltransferase homologs	F	Contig1	OEOE1322	COG0856	39	3e-04
Orotate phosphoribosyltransferase homologs	F	Contig1	OEOE1543	COG0856	36	0.004
Predicted nucleotide kinase (related to CMP and AMP kinase)	F	Contig1	OEOE0676	COG1936	38	5e-04
Protein involved in ribonucleotide reduction	F	Contig1	OEOE0138	COG1780	91	4e-20
Protein involved in ribonucleotide reduction	F	Contig1	OEOE0459	COG1780	44	4e-06

PURINE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Adenylosuccinate lyase	F	Contig1	OEOE0029	COG0015	111	1e-25
Adenylosuccinate lyase	F	Contig1	OEOE1125	COG0015	494	1.0e-141
Adenylosuccinate synthase	F	Contig1	OEOE1126	COG0104	590	1.0e-170
AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)	F	Contig1	OEOE0261	COG0138	38	0.003
AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)	F	Contig1	OEOE1129	COG0138	668	0.0
Folate-dependent phosphoribosylglycinamide formyltransferase PurN	F	Contig1	OEOE0787	COG0299	73	3e-14
Folate-dependent phosphoribosylglycinamide formyltransferase PurN	F	Contig1	OEOE1130	COG0299	229	1e-61
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	Contig1	OEOE0261	COG0027	59	1e-09
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	Contig1	OEOE0672	COG0027	37	0.003
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	Contig1	OEOE1137	COG0027	150	2e-37
Glutamine phosphoribosylpyrophosphate amidotransferase	F	Contig1	OEOE0635	COG0034	105	1e-23
Glutamine phosphoribosylpyrophosphate amidotransferase	F	Contig1	OEOE1322	COG0034	49	2e-07
GMP synthase - Glutamine amidotransferase domain	F	Contig1	OEOE0260	COG0518	60	3e-10
GMP synthase - Glutamine amidotransferase domain	F	Contig1	OEOE1031	COG0518	61	6e-11
GMP synthase - Glutamine amidotransferase domain	F	Contig1	OEOE1123	COG0518	189	4e-49
GMP synthase - Glutamine amidotransferase domain	F	Contig1	OEOE1134	COG0518	43	2e-05
GMP synthase - Glutamine amidotransferase domain	F	Contig1	OEOE1600	COG0518	37	0.001
GMP synthase PP-ATPase domain/subunit	F	Contig1	OEOE1123	COG0519	537	1.0e-154
IMP dehydrogenase/GMP reductase	F	Contig1	OEOE0535	COG0516	91	7e-20
IMP dehydrogenase/GMP reductase	F	Contig1	OEOE1127	COG0516	125	5e-30
Phosphoribosylamine-glycine ligase	F	Contig1	OEOE0261	COG0151	57	5e-09
Phosphoribosylamine-glycine ligase	F	Contig1	OEOE0672	COG0151	38	0.001
Phosphoribosylamine-glycine ligase	F	Contig1	OEOE1137	COG0151	42	8e-05
Phosphoribosylamine-glycine ligase	F	Contig1	OEOE1585	COG0151	51	1e-07
Phosphoribosylaminoimidazole (AIR) synthetase	F	Contig1	OEOE1131	COG0150	393	1.0e-110
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	Contig1	OEOE0261	COG0026	52	3e-07
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	Contig1	OEOE0672	COG0026	48	1e-06
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	Contig1	OEOE1136	COG0026	35	0.004
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	Contig1	OEOE1137	COG0026	420	1.0e-119
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	Contig1	OEOE1585	COG0026	54	2e-08
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	Contig1	OEOE1672	COG0026	34	0.010
Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase	F	Contig1	OEOE1136	COG0152	230	5e-62
Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	F	Contig1	OEOE1138	COG0041	212	1e-56
Phosphoribosylformylglycinamidine (FGAM) synthase glutamine amidotransferase domain	F	Contig1	OEOE1037	COG0047	37	0.001
Phosphoribosylformylglycinamidine (FGAM) synthase glutamine amidotransferase domain	F	Contig1	OEOE1134	COG0047	287	5e-79
Phosphoribosylformylglycinamidine (FGAM) synthase PurS component	F	Contig1	OEOE1135	COG1828	82	7e-18
Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain	F	Contig1	OEOE1131	COG0046	44	2e-05
Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain	F	Contig1	OEOE1133	COG0046	802	0.0
Phosphoribosylpyrophosphate synthetase	F	Contig1	OEOE0160	COG0462	368	1.0e-103
Phosphoribosylpyrophosphate synthetase	F	Contig1	OEOE0187	COG0462	42	2e-05
Phosphoribosylpyrophosphate synthetase	F	Contig1	OEOE0263	COG0462	50	1e-07
Phosphoribosylpyrophosphate synthetase	F	Contig1	OEOE1069	COG0462	36	0.001
Phosphoribosylpyrophosphate synthetase	F	Contig1	OEOE1124	COG0462	46	2e-06
Phosphoribosylpyrophosphate synthetase	F	Contig1	OEOE1322	COG0462	41	6e-05
Phosphoribosylpyrophosphate synthetase	F	Contig1	OEOE1579	COG0462	38	5e-04

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Purine-cytosine permease and related protein	F	Contig1	OEOE1469	COG1457	114	1e-26

PURINE SALVAGE

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	Contig1	OEOE0160	COG0503	36	0.003
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	Contig1	OEOE0263	COG0503	63	2e-11
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	Contig1	OEOE0322	COG0503	38	7e-04
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	Contig1	OEOE0537	COG0503	132	2e-32
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	Contig1	OEOE1069	COG0503	175	2e-45
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	Contig1	OEOE1543	COG0503	107	1e-24
Formyltetrahydrofolate hydrolase	F	Contig1	OEOE0787	COG0788	59	6e-10
Formyltetrahydrofolate hydrolase	F	Contig1	OEOE0944	COG0788	49	6e-08
Formyltetrahydrofolate hydrolase	F	Contig1	OEOE1130	COG0788	105	3e-24
Hypoxanthine-guanine phosphoribosyltransferase	F	Contig1	OEOE0160	COG0634	41	1e-04
Hypoxanthine-guanine phosphoribosyltransferase	F	Contig1	OEOE0187	COG0634	205	1e-54
Hypoxanthine-guanine phosphoribosyltransferase	F	Contig1	OEOE1124	COG0634	174	5e-45
Hypoxanthine-guanine phosphoribosyltransferase	F	Contig1	OEOE1322	COG0634	39	3e-04
Hypoxanthine-guanine phosphoribosyltransferase	F	Contig1	OEOE1579	COG0634	39	3e-04

PYRIMIDINE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Adenylate kinase and related kinase	F	Contig1	OEOE0153	COG0563	38	3e-04
Adenylate kinase and related kinase	F	Contig1	OEOE0269	COG0563	35	0.007
Adenylate kinase and related kinase	F	Contig1	OEOE0615	COG0563	171	2e-44
Adenylate kinase and related kinase	F	Contig1	OEOE1008	COG0563	48	6e-07
Adenylate kinase and related kinase	F	Contig1	OEOE1729	COG0563	36	0.007
Aspartate carbamoyltransferase catalytic chain	F	Contig1	OEOE0258	COG0540	299	2e-82
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	Contig1	OEOE0261	COG0458	544	1.0e-155
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	Contig1	OEOE0672	COG0458	58	1e-09
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	Contig1	OEOE1137	COG0458	50	3e-07
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	Contig1	OEOE1585	COG0458	85	1e-17
Carbamoylphosphate synthase small subunit	F	Contig1	OEOE0260	COG0505	495	1.0e-141
Carbamoylphosphate synthase small subunit	F	Contig1	OEOE1031	COG0505	66	3e-12
Carbamoylphosphate synthase small subunit	F	Contig1	OEOE1123	COG0505	50	3e-07
Carbamoylphosphate synthase small subunit	F	Contig1	OEOE1786	COG0505	37	0.005
CTP synthase (UTP-ammonia lyase)	F	Contig1	OEOE1031	COG0504	53	2e-08
CTP synthase (UTP-ammonia lyase)	F	Contig1	OEOE1134	COG0504	35	0.006
CTP synthase (UTP-ammonia lyase)	F	Contig1	OEOE1786	COG0504	852	0.0
Cytidylate kinase	F	Contig1	OEOE0153	COG1102	39	3e-04
Cytidylate kinase	F	Contig1	OEOE0615	COG1102	38	4e-04
Cytidylate kinase	F	Contig1	OEOE0676	COG1102	35	0.004
Cytidylate kinase	F	Contig1	OEOE0849	COG1102	34	0.006
Cytidylate kinase	F	Contig1	OEOE1008	COG1102	68	6e-13
Cytidylate kinase	F	Contig1	OEOE1008	COG0283	252	1e-68
Dihydroorotase and related cyclic amidohydrolase	F	Contig1	OEOE0158	COG0044	36	0.007
Dihydroorotase and related cyclic amidohydrolase	F	Contig1	OEOE0259	COG0044	417	1.0e-117
Dihydroorotase and related cyclic amidohydrolase	F	Contig1	OEOE1462	COG0044	50	6e-07
Dihydroorotase and related cyclic amidohydrolase	F	Contig1	OEOE1728	COG0044	43	4e-05
Dihydroorotase	F	Contig1	OEOE0259	COG0418	56	7e-09
Dihydroorotate dehydrogenase	F	Contig1	OEOE0264	COG0167	234	6e-63
Dihydroorotate dehydrogenase	F	Contig1	OEOE0516	COG0167	36	0.004
Dihydroorotate dehydrogenase	F	Contig1	OEOE0535	COG0167	36	0.004
Dihydroorotate dehydrogenase	F	Contig1	OEOE1591	COG0167	36	0.004
Orotate phosphoribosyltransferase	F	Contig1	OEOE0160	COG0461	39	6e-04
Orotate phosphoribosyltransferase	F	Contig1	OEOE0263	COG0461	174	4e-45
Orotate phosphoribosyltransferase	F	Contig1	OEOE0537	COG0461	56	2e-09
Orotate phosphoribosyltransferase	F	Contig1	OEOE1069	COG0461	55	3e-09
Orotate phosphoribosyltransferase	F	Contig1	OEOE1322	COG0461	38	7e-04
Orotate phosphoribosyltransferase	F	Contig1	OEOE1543	COG0461	41	1e-04
Orotate phosphoribosyltransferase	F	Contig1	OEOE1579	COG0461	36	0.002
Orotidine-5'-phosphate decarboxylase	F	Contig1	OEOE0131	COG0284	38	4e-04
Orotidine-5'-phosphate decarboxylase	F	Contig1	OEOE0262	COG0284	200	9e-53
Orotidine-5'-phosphate decarboxylase	F	Contig1	OEOE0790	COG0284	34	0.009
Uridylate kinase	F	Contig1	OEOE0947	COG0528	46	3e-06
Uridylate kinase	F	Contig1	OEOE0977	COG0528	304	3e-84
Uridylate kinase	F	Contig1	OEOE1544	COG0528	36	0.008

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	F	Contig1	OEOE0187	COG2065	45	4e-06
Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	F	Contig1	OEOE1069	COG2065	34	0.006
Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	F	Contig1	OEOE1124	COG2065	39	2e-04
Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	F	Contig1	OEOE1579	COG2065	38	7e-04

PYRIMIDINE SALVAGE

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Cytidine deaminase	F	Contig1	OEOE1731	COG0295	133	6e-33
Cytosine deaminase and related metal-dependent hydrolase	F	Contig1	OEOE0158	COG0402	37	0.004
Cytosine deaminase and related metal-dependent hydrolase	F	Contig1	OEOE0259	COG0402	54	2e-08
Cytosine deaminase and related metal-dependent hydrolase	F	Contig1	OEOE1462	COG0402	51	3e-07
Cytosine deaminase and related metal-dependent hydrolase	F	Contig1	OEOE1728	COG0402	47	2e-06
Nucleoside phosphorylase	F	Contig1	OEOE1108	COG0775	191	3e-50
Purine-nucleoside phosphorylase	F	Contig1	OEOE1108	COG0813	45	5e-06
Thymidine kinase	F	Contig1	OEOE1598	COG1435	232	1e-62
Uracil phosphoribosyltransferase	F	Contig1	OEOE0160	COG0035	37	0.002
Uracil phosphoribosyltransferase	F	Contig1	OEOE1069	COG0035	34	0.008
Uracil phosphoribosyltransferase	F	Contig1	OEOE1579	COG0035	302	9e-84
Uridine kinase	F	Contig1	OEOE0676	COG0572	43	1e-05
Uridine kinase	F	Contig1	OEOE1008	COG0572	44	7e-06
Uridine kinase	F	Contig1	OEOE1033	COG0572	243	7e-66
Uridine kinase	F	Contig1	OEOE1603	COG0572	74	9e-15

THIAMINE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Uncharacterized protein of thiazole biosynthesis	F	Contig1	OEOE1036	COG2022	44	9e-06

THYMIDYLATE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
dUTPase	F	Contig1	OEOE0316	COG0756	128	2e-31
Oxygen-sensitive ribonucleoside-triphosphate reductase	F	Contig1	OEOE1116	COG1328	764	0.0
Ribonucleotide reductase alpha subunit	F	Contig1	OEOE0140	COG0209	546	1.0e-156
Ribonucleotide reductase beta subunit	F	Contig1	OEOE0141	COG0208	300	9e-83
Thymidylate kinase	F	Contig1	OEOE0437	COG0125	41	1e-04
Thymidylate kinase	F	Contig1	OEOE0849	COG0125	48	8e-07
Thymidylate kinase	F	Contig1	OEOE1407	COG0125	211	3e-56
Thymidylate kinase	F	Contig1	OEOE1432	COG0125	37	0.001
Thymidylate synthase	F	Contig1	OEOE0782	COG0207	314	7e-87

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Uridine phosphorylase	F	Contig1	OEOE1108	COG2820	41	1e-04
Xanthine/uracil permease	F	Contig1	OEOE0376	COG2233	314	8e-87
Xanthine/uracil permease	F	Contig1	OEOE0536	COG2233	371	1.0e-104
Xanthine/uracil permease	F	Contig1	OEOE0783	COG2233	42	8e-05
Xanthine/uracil permease	F	Contig1	OEOE1119	COG2233	37	0.004
Xanthosine triphosphate pyrophosphatase	F	Contig1	OEOE0320	COG0127	186	8e-49

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