Lipid Metabolism

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
1-acyl-sn-glycerol-3-phosphate acyltransferase	I	Contig6	Nwi0579	COG0204	109	3e-25
3-hydroxy-3-methylglutaryl CoA synthase	I	Contig6	Nwi1407	COG3425	102	4e-23
3-hydroxy-3-methylglutaryl CoA synthase	I	Contig6	Nwi2160	COG3425	38	0.002
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig6	Nwi0037	COG2084	40	2e-04
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig6	Nwi0469	COG2084	37	0.002
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig6	Nwi0582	COG2084	51	1e-07
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig6	Nwi1213	COG2084	294	4e-81
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig6	Nwi2156	COG2084	266	1e-72
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig6	Nwi2341	COG2084	36	0.004
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig6	Nwi2380	COG2084	37	0.003
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig6	Nwi2642	COG2084	102	5e-23
3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	I	Contig6	Nwi0034	COG0764	140	6e-35
3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	I	Contig6	Nwi1245	COG0764	107	5e-25
3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	I	Contig6	Nwi1578	COG0764	138	2e-34
3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	I	Contig6	Nwi1849	COG0764	143	4e-36
Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	I	Contig6	Nwi0053	COG4799	73	2e-14
Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	I	Contig6	Nwi0392	COG4799	64	1e-11
Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	I	Contig6	Nwi1401	COG4799	676	0.0
Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	I	Contig6	Nwi1605	COG4799	616	1.0e-177
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig6	Nwi0423	COG4770	36	0.004
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig6	Nwi1055	COG4770	41	1e-04
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig6	Nwi1604	COG4770	747	0.0
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig6	Nwi1736	COG4770	796	0.0
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig6	Nwi1752	COG4770	60	1e-10
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig6	Nwi1753	COG4770	580	1.0e-167
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig6	Nwi2449	COG4770	63	1e-10
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig6	Nwi2552	COG4770	36	0.004
Acyl carrier protein phosphodiesterase	I	Contig6	Nwi0200	COG1182	54	7e-09
Acyl carrier protein phosphodiesterase	I	Contig6	Nwi1820	COG1182	36	0.002
Acyl CoA:acetate/3-ketoacid CoA transferase alpha subunit	I	Contig6	Nwi1010	COG1788	308	3e-85
Acyl CoA:acetate/3-ketoacid CoA transferase beta subunit	I	Contig6	Nwi1011	COG2057	293	6e-81
Acyl CoA:acetate/3-ketoacid CoA transferase	I	Contig6	Nwi1010	COG4670	97	2e-21
Acyl CoA:acetate/3-ketoacid CoA transferase	I	Contig6	Nwi1011	COG4670	62	4e-11
Acyl-CoA dehydrogenase	I	Contig6	Nwi0459	COG1960	76	5e-15
Acyl-CoA dehydrogenase	I	Contig6	Nwi0608	COG1960	295	4e-81
Acyl-CoA dehydrogenase	I	Contig6	Nwi0637	COG1960	237	1e-63
Acyl-CoA dehydrogenase	I	Contig6	Nwi0937	COG1960	102	4e-23
Acyl-CoA dehydrogenase	I	Contig6	Nwi2006	COG1960	174	1e-44
Acyl-CoA dehydrogenase	I	Contig6	Nwi2158	COG1960	304	5e-84
Acyl-CoA dehydrogenase	I	Contig6	Nwi2995	COG1960	184	2e-47
Acyl-CoA dehydrogenase	I	Contig6	Nwi3018	COG1960	340	9e-95
Acyl-CoA hydrolase	I	Contig6	Nwi2723	COG1607	34	0.003
Acyl-CoA hydrolase	I	Contig6	Nwi2992	COG1607	146	8e-37
Acyl-CoA thioesterase	I	Contig6	Nwi0078	COG1946	363	1.0e-101
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig6	Nwi0467	COG0365	668	0.0
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig6	Nwi0617	COG0365	210	2e-55
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig6	Nwi1511	COG0365	48	1e-06
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig6	Nwi1765	COG0365	43	4e-05
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig6	Nwi2300	COG0365	95	8e-21
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig6	Nwi2684	COG0365	267	2e-72
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig6	Nwi2797	COG0365	263	2e-71
Acyl dehydratase	I	Contig6	Nwi2155	COG2030	102	1e-23
Acyl dehydratase	I	Contig6	Nwi2290	COG2030	126	6e-31
Acyl dehydratase	I	Contig6	Nwi2507	COG2030	97	8e-22
Acyl dehydratase	I	Contig6	Nwi2508	COG2030	79	2e-16
CDP-diglyceride synthetase	I	Contig6	Nwi1854	COG0575	127	7e-31
Cytidylyltransferase	I	Contig6	Nwi1071	COG0615	81	1e-16
Cytidylyltransferase	I	Contig6	Nwi1799	COG0615	33	0.009

DEOXYXYLULOSE PATHWAY OF TERPENOID BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
1-deoxy-D-xylulose 5-phosphate reductoisomerase	I	Contig6	Nwi1853	COG0743	477	1.0e-136
2C-methyl-D-erythritol 2 4-cyclodiphosphate synthase	I	Contig6	Nwi1442	COG0245	213	1e-56
4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase	I	Contig6	Nwi2593	COG1947	206	2e-54
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig6	Nwi0048	COG1211	36	0.002
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig6	Nwi0545	COG1211	46	3e-06
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig6	Nwi1442	COG1211	226	3e-60
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig6	Nwi1784	COG1211	48	1e-06
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig6	Nwi2199	COG1211	52	1e-07
Deoxyxylulose-5-phosphate synthase	I	Contig6	Nwi0633	COG1154	913	0.0
Deoxyxylulose-5-phosphate synthase	I	Contig6	Nwi1817	COG1154	97	2e-21
Deoxyxylulose-5-phosphate synthase	I	Contig6	Nwi1818	COG1154	41	1e-04
Deoxyxylulose-5-phosphate synthase	I	Contig6	Nwi2734	COG1154	72	2e-13

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Enoyl reductase domain of yeast-type FAS1	I	Contig6	Nwi3001	COG4981	51	1e-07
Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis	I	Contig6	Nwi0494	COG0821	456	1.0e-129
Esterase/lipase	I	Contig6	Nwi0070	COG0657	34	0.009

FATTY ACID BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
3-hydroxyacyl-CoA dehydrogenase	I	Contig6	Nwi0469	COG1250	40	2e-04
3-hydroxyacyl-CoA dehydrogenase	I	Contig6	Nwi0543	COG1250	36	0.007
3-hydroxyacyl-CoA dehydrogenase	I	Contig6	Nwi0755	COG1250	359	1.0e-100
3-hydroxyacyl-CoA dehydrogenase	I	Contig6	Nwi2464	COG1250	39	7e-04
3-hydroxyacyl-CoA dehydrogenase	I	Contig6	Nwi2993	COG1250	242	6e-65
3-oxoacyl-(acyl-carrier-protein) synthase	I	Contig6	Nwi0033	COG0304	428	1.0e-121
3-oxoacyl-(acyl-carrier-protein) synthase	I	Contig6	Nwi1243	COG0304	391	1.0e-110
3-oxoacyl-(acyl-carrier-protein) synthase	I	Contig6	Nwi1244	COG0304	160	2e-40
3-oxoacyl-(acyl-carrier-protein) synthase	I	Contig6	Nwi1686	COG0304	482	1.0e-137
3-oxoacyl-(acyl-carrier-protein) synthase	I	Contig6	Nwi2160	COG0304	57	2e-09
3-oxoacyl-(acyl-carrier-protein) synthase	I	Contig6	Nwi3060	COG0304	50	3e-07
Acetyl-CoA acetyltransferase	I	Contig6	Nwi0279	COG0183	260	1e-70
Acetyl-CoA acetyltransferase	I	Contig6	Nwi1407	COG0183	36	0.003
Acetyl-CoA acetyltransferase	I	Contig6	Nwi1686	COG0183	38	0.002
Acetyl-CoA acetyltransferase	I	Contig6	Nwi2160	COG0183	247	9e-67
Acetyl-CoA acetyltransferase	I	Contig6	Nwi2994	COG0183	234	7e-63
Acetyl-CoA acetyltransferase	I	Contig6	Nwi3060	COG0183	331	4e-92
Acetyl-CoA carboxylase alpha subunit	I	Contig6	Nwi0392	COG0825	425	1.0e-120
Acetyl-CoA carboxylase alpha subunit	I	Contig6	Nwi1401	COG0825	64	3e-11
Acetyl-CoA carboxylase alpha subunit	I	Contig6	Nwi1605	COG0825	52	1e-07
Acetyl-CoA carboxylase beta subunit	I	Contig6	Nwi0053	COG0777	398	1.0e-112
Acetyl-CoA carboxylase beta subunit	I	Contig6	Nwi1401	COG0777	91	2e-19
Acetyl-CoA carboxylase beta subunit	I	Contig6	Nwi1605	COG0777	47	4e-06
Acyl carrier protein	I	Contig6	Nwi1246	COG0236	56	5e-10
Acyl carrier protein	I	Contig6	Nwi1687	COG0236	67	3e-13
Acyl carrier protein	I	Contig6	Nwi2299	COG0236	38	0.002
(acyl-carrier-protein) S-malonyltransferase	I	Contig6	Nwi1690	COG0331	321	3e-89
(acyl-carrier-protein) S-malonyltransferase	I	Contig6	Nwi2280	COG0331	37	0.003
Biotin carboxylase	I	Contig6	Nwi0897	COG0439	45	2e-05
Biotin carboxylase	I	Contig6	Nwi1055	COG0439	60	2e-10
Biotin carboxylase	I	Contig6	Nwi1604	COG0439	529	1.0e-151
Biotin carboxylase	I	Contig6	Nwi1736	COG0439	532	1.0e-152
Biotin carboxylase	I	Contig6	Nwi1753	COG0439	592	1.0e-170
Biotin carboxylase	I	Contig6	Nwi2449	COG0439	81	3e-16
Biotin carboxylase	I	Contig6	Nwi2552	COG0439	59	7e-10
Biotin carboxyl carrier protein	I	Contig6	Nwi0423	COG0511	44	3e-05
Biotin carboxyl carrier protein	I	Contig6	Nwi1604	COG0511	69	7e-13
Biotin carboxyl carrier protein	I	Contig6	Nwi1736	COG0511	76	7e-15
Biotin carboxyl carrier protein	I	Contig6	Nwi1752	COG0511	105	2e-24
Biotin carboxyl carrier protein	I	Contig6	Nwi1816	COG0511	44	3e-05
Biotin carboxyl carrier protein	I	Contig6	Nwi1817	COG0511	40	5e-04
Enoyl-CoA hydratase/carnithine racemase	I	Contig6	Nwi0636	COG1024	167	8e-43
Enoyl-CoA hydratase/carnithine racemase	I	Contig6	Nwi2157	COG1024	126	3e-30
Enoyl-CoA hydratase/carnithine racemase	I	Contig6	Nwi2252	COG1024	216	1e-57
Enoyl-CoA hydratase/carnithine racemase	I	Contig6	Nwi2993	COG1024	143	4e-35

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Fatty acid/phospholipid biosynthesis enzyme	I	Contig6	Nwi1406	COG0416	396	1.0e-111
Isopentenyldiphosphate isomerase	I	Contig6	Nwi0387	COG1443	36	9e-04
Long-chain acyl-CoA synthetase (AMP-forming)	I	Contig6	Nwi0467	COG1022	121	2e-28
Long-chain acyl-CoA synthetase (AMP-forming)	I	Contig6	Nwi0617	COG1022	184	1e-47
Long-chain acyl-CoA synthetase (AMP-forming)	I	Contig6	Nwi2300	COG1022	64	2e-11
Long-chain acyl-CoA synthetase (AMP-forming)	I	Contig6	Nwi2684	COG1022	247	2e-66
Long-chain acyl-CoA synthetase (AMP-forming)	I	Contig6	Nwi2797	COG1022	210	2e-55
Lysophospholipase	I	Contig6	Nwi0070	COG2267	42	5e-05
Lysophospholipase	I	Contig6	Nwi1666	COG2267	35	0.003
Lysophospholipase	I	Contig6	Nwi2178	COG2267	54	1e-08
Lysophospholipase	I	Contig6	Nwi2207	COG2267	48	5e-07
Lysophospholipase	I	Contig6	Nwi2280	COG2267	47	2e-06
Lysophospholipase	I	Contig6	Nwi2951	COG2267	201	8e-53

MENAQUINONE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig6	Nwi0467	COG0318	271	9e-74
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig6	Nwi0617	COG0318	405	1.0e-114
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig6	Nwi1511	COG0318	110	2e-25
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig6	Nwi1765	COG0318	46	4e-06
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig6	Nwi2300	COG0318	147	1e-36
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig6	Nwi2684	COG0318	478	1.0e-136
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig6	Nwi2797	COG0318	384	1.0e-108

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Methylmalonyl-CoA mutase C-terminal domain/subunit (cobalamin-binding)	I	Contig6	Nwi0283	COG2185	49	2e-06
Methylmalonyl-CoA mutase C-terminal domain/subunit (cobalamin-binding)	I	Contig6	Nwi2236	COG2185	49	9e-07
Methylmalonyl-CoA mutase C-terminal domain/subunit (cobalamin-binding)	I	Contig6	Nwi2238	COG2185	161	2e-40
Methylmalonyl-CoA mutase N-terminal domain/subunit	I	Contig6	Nwi2236	COG1884	259	5e-70
Methylmalonyl-CoA mutase N-terminal domain/subunit	I	Contig6	Nwi2238	COG1884	724	0.0
Oligoketide cyclase/lipid transport protein	I	Contig6	Nwi1440	COG2867	161	3e-41
Penicillin tolerance protein	I	Contig6	Nwi2266	COG0761	389	1.0e-109
Penicillin tolerance protein	I	Contig6	Nwi2689	COG0761	391	1.0e-110
Phosphatidylglycerophosphate synthase	I	Contig6	Nwi1235	COG0558	50	3e-07
Phosphatidylglycerophosphate synthase	I	Contig6	Nwi1596	COG0558	68	5e-13
Phosphatidylglycerophosphate synthase	I	Contig6	Nwi2525	COG0558	110	8e-26
Phosphatidylserine decarboxylase	I	Contig6	Nwi0699	COG0688	111	5e-26
Phosphatidylserine decarboxylase	I	Contig6	Nwi1234	COG0688	208	4e-55
Phosphatidylserine synthase	I	Contig6	Nwi1235	COG1183	181	7e-47
Phosphatidylserine synthase	I	Contig6	Nwi1506	COG1183	104	8e-24
Phosphatidylserine synthase	I	Contig6	Nwi1596	COG1183	39	2e-04
Phospholipid N-methyltransferase	I	Contig6	Nwi0199	COG3963	157	6e-40
Phospholipid N-methyltransferase	I	Contig6	Nwi1682	COG3963	39	5e-04
Phospholipid N-methyltransferase	I	Contig6	Nwi3082	COG3963	37	0.003
Phosphopantetheinyl transferase (holo-ACP synthase)	I	Contig6	Nwi1920	COG0736	133	4e-33
Phytoene/squalene synthetase	I	Contig6	Nwi1766	COG1562	132	3e-32
Phytoene/squalene synthetase	I	Contig6	Nwi2271	COG1562	120	2e-28
Phytoene/squalene synthetase	I	Contig6	Nwi2272	COG1562	103	1e-23
Poly(3-hydroxyalkanoate) synthetase	I	Contig6	Nwi0130	COG3243	50	3e-07
Poly(3-hydroxyalkanoate) synthetase	I	Contig6	Nwi1650	COG3243	564	1.0e-162
Poly-beta-hydroxyalkanoate depolymerase	I	Contig6	Nwi0130	COG4553	611	1.0e-176
Predicted acyltransferase	I	Contig6	Nwi0136	COG1835	43	3e-05
Predicted acyltransferase	I	Contig6	Nwi0358	COG1835	38	0.001
Squalene cyclase	I	Contig6	Nwi2269	COG1657	238	1e-63
Undecaprenyl pyrophosphate synthase	I	Contig6	Nwi1855	COG0020	304	4e-84

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