Coenzyme Metabolism

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
5 10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	H	Contig6	Nwi0480	COG0190	359	1.0e-100
5 10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	H	Contig6	Nwi0995	COG0190	35	0.009
5-formyltetrahydrofolate cyclo-ligase	H	Contig6	Nwi2731	COG0212	144	3e-36
6-pyruvoyl-tetrahydropterin synthase	H	Contig6	Nwi2620	COG0720	93	4e-21
7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	H	Contig6	Nwi2235	COG0801	166	8e-43
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi0174	COG1120	164	1e-41
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi0292	COG1120	152	7e-38
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi0322	COG1120	108	2e-25
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi0327	COG1120	134	1e-32
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi0332	COG1120	143	1e-35
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi0338	COG1120	150	6e-38
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi0415	COG1120	149	1e-37
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi0458	COG1120	139	1e-34
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi0509	COG1120	161	7e-41
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi0535	COG1120	126	8e-30
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi0576	COG1120	137	5e-34
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi0611	COG1120	112	9e-26
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi0668	COG1120	157	7e-40
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi0669	COG1120	125	4e-30
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi0671	COG1120	149	2e-37
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi0684	COG1120	106	9e-25
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi0685	COG1120	34	0.002
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi0914	COG1120	182	2e-47
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi0962	COG1120	126	4e-30
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi1006	COG1120	174	1e-44
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi1064	COG1120	138	9e-34
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi1233	COG1120	144	1e-35
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi1526	COG1120	158	4e-40
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi1568	COG1120	63	9e-11
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi1663	COG1120	97	1e-21
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi1673	COG1120	101	1e-22
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi1863	COG1120	132	3e-32
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi2041	COG1120	136	7e-33
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi2074	COG1120	259	2e-70
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi2153	COG1120	117	2e-27
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi2211	COG1120	121	8e-29
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi2212	COG1120	151	6e-38
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi2322	COG1120	218	5e-58
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi2339	COG1120	166	1e-42
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi2361	COG1120	157	8e-40
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi2485	COG1120	114	1e-26
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi2670	COG1120	129	2e-31
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi2681	COG1120	127	2e-30
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi2746	COG1120	159	7e-40
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi2757	COG1120	179	2e-46
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig6	Nwi3049	COG1120	242	2e-65
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi0174	COG4138	87	3e-18
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi0292	COG4138	72	1e-13
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi0322	COG4138	54	7e-09
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi0327	COG4138	68	2e-12
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi0332	COG4138	59	4e-10
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi0338	COG4138	78	6e-16
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi0415	COG4138	82	4e-17
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi0458	COG4138	66	4e-12
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi0509	COG4138	68	9e-13
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi0535	COG4138	71	3e-13
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi0576	COG4138	62	4e-11
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi0668	COG4138	68	7e-13
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi0669	COG4138	57	2e-09
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi0671	COG4138	66	3e-12
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi0684	COG4138	44	5e-06
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi0914	COG4138	91	9e-20
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi0962	COG4138	70	7e-13
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi1006	COG4138	83	4e-17
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi1064	COG4138	84	4e-17
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi1233	COG4138	67	5e-12
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi1526	COG4138	63	2e-11
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi1568	COG4138	49	2e-06
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi1663	COG4138	61	9e-11
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi1673	COG4138	57	4e-09
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi1863	COG4138	53	3e-08
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi2041	COG4138	63	5e-11
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi2074	COG4138	106	2e-24
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi2153	COG4138	61	3e-10
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi2211	COG4138	45	8e-06
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi2212	COG4138	79	4e-16
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi2322	COG4138	116	2e-27
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi2339	COG4138	84	1e-17
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi2361	COG4138	78	6e-16
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi2485	COG4138	57	3e-09
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi2670	COG4138	59	3e-10
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi2681	COG4138	75	2e-14
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi2746	COG4138	79	9e-16
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi2757	COG4138	80	2e-16
ABC-type cobalamin transport system ATPase component	H	Contig6	Nwi3049	COG4138	109	2e-25
ABC-type cobalamin transport system permease component	H	Contig6	Nwi2075	COG4139	148	4e-37
ABC-type cobalamin transport system permease component	H	Contig6	Nwi2323	COG4139	174	7e-45
ABC-type cobalamin transport system permease component	H	Contig6	Nwi3048	COG4139	138	4e-34
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi0174	COG3840	109	3e-25
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi0292	COG3840	121	2e-28
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi0322	COG3840	88	6e-19
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi0327	COG3840	125	8e-30
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi0332	COG3840	140	1e-34
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi0338	COG3840	147	5e-37
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi0415	COG3840	138	3e-34
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi0458	COG3840	147	9e-37
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi0509	COG3840	107	1e-24
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi0535	COG3840	101	2e-22
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi0576	COG3840	102	2e-23
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi0611	COG3840	96	7e-21
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi0668	COG3840	104	6e-24
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi0669	COG3840	75	4e-15
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi0671	COG3840	153	1e-38
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi0684	COG3840	109	1e-25
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi0685	COG3840	39	7e-05
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi0914	COG3840	115	4e-27
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi0962	COG3840	81	2e-16
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi1006	COG3840	190	2e-49
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi1064	COG3840	114	2e-26
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi1233	COG3840	116	4e-27
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi1526	COG3840	162	2e-41
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi1568	COG3840	45	3e-05
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi1663	COG3840	61	7e-11
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi1673	COG3840	61	3e-10
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi1863	COG3840	115	3e-27
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi2041	COG3840	112	7e-26
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi2074	COG3840	104	6e-24
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi2098	COG3840	36	0.003
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi2153	COG3840	85	1e-17
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi2211	COG3840	88	7e-19
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi2212	COG3840	101	4e-23
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi2322	COG3840	103	1e-23
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi2339	COG3840	136	1e-33
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi2361	COG3840	112	4e-26
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi2485	COG3840	72	8e-14
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi2670	COG3840	128	3e-31
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi2681	COG3840	110	3e-25
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi2746	COG3840	121	1e-28
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi2757	COG3840	181	8e-47
ABC-type thiamine transport system ATPase component	H	Contig6	Nwi3049	COG3840	117	7e-28
ABC-type tungstate transport system periplasmic component	H	Contig6	Nwi0339	COG4662	83	3e-17
ABC-type tungstate transport system periplasmic component	H	Contig6	Nwi0508	COG4662	40	2e-04
ABC-type tungstate transport system periplasmic component	H	Contig6	Nwi2758	COG4662	78	9e-16
ABC-type tungstate transport system periplasmic component	H	Contig6	Nwi2759	COG4662	83	2e-17

BIOTIN BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
7-keto-8-aminopelargonate synthetase	H	Contig6	Nwi0139	COG0156	41	2e-04
7-keto-8-aminopelargonate synthetase	H	Contig6	Nwi0242	COG0156	436	1.0e-123
7-keto-8-aminopelargonate synthetase	H	Contig6	Nwi0592	COG0156	42	7e-05
7-keto-8-aminopelargonate synthetase	H	Contig6	Nwi0642	COG0156	44	2e-05
7-keto-8-aminopelargonate synthetase	H	Contig6	Nwi1077	COG0156	36	0.005
7-keto-8-aminopelargonate synthetase	H	Contig6	Nwi1420	COG0156	51	2e-07
7-keto-8-aminopelargonate synthetase	H	Contig6	Nwi1727	COG0156	36	0.004
7-keto-8-aminopelargonate synthetase	H	Contig6	Nwi2263	COG0156	39	5e-04
7-keto-8-aminopelargonate synthetase	H	Contig6	Nwi2388	COG0156	39	9e-04
7-keto-8-aminopelargonate synthetase	H	Contig6	Nwi2421	COG0156	352	2e-98
7-keto-8-aminopelargonate synthetase	H	Contig6	Nwi2516	COG0156	46	4e-06
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	H	Contig6	Nwi0242	COG0161	37	0.003
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	H	Contig6	Nwi0513	COG0161	288	7e-79
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	H	Contig6	Nwi0698	COG0161	106	3e-24
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	H	Contig6	Nwi2263	COG0161	290	2e-79
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	H	Contig6	Nwi2388	COG0161	134	1e-32
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	H	Contig6	Nwi2419	COG0161	494	1.0e-141
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	H	Contig6	Nwi2516	COG0161	305	4e-84
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	H	Contig6	Nwi2537	COG0161	474	1.0e-135
Biotin-(acetyl-CoA carboxylase) ligase	H	Contig6	Nwi1873	COG0340	179	2e-46
Biotin synthase	H	Contig6	Nwi0243	COG0502	396	1.0e-111
Biotin synthase	H	Contig6	Nwi1439	COG0502	61	8e-11
Biotin synthase	H	Contig6	Nwi2258	COG0502	39	7e-04
Biotin synthase	H	Contig6	Nwi2276	COG0502	47	4e-06
Dethiobiotin synthetase	H	Contig6	Nwi2420	COG0132	192	2e-50

COBALAMIN BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Cobyric acid synthase	H	Contig6	Nwi0124	COG1492	38	8e-04
Cobyric acid synthase	H	Contig6	Nwi2391	COG1492	34	0.006
Cobyrinic acid a c-diamide synthase	H	Contig6	Nwi0532	COG1797	35	0.004
Cobyrinic acid a c-diamide synthase	H	Contig6	Nwi1306	COG1797	38	5e-04
Cobyrinic acid a c-diamide synthase	H	Contig6	Nwi2391	COG1797	34	0.007
Cobyrinic acid a c-diamide synthase	H	Contig6	Nwi2779	COG1797	36	0.008
Precorrin-2 methylase	H	Contig6	Nwi0115	COG2243	37	0.002
Precorrin-2 methylase	H	Contig6	Nwi2762	COG2243	80	5e-16
Precorrin-3B methylase	H	Contig6	Nwi2762	COG1010	73	5e-14
Precorrin-6B methylase 1	H	Contig6	Nwi2762	COG2241	58	2e-09
Precorrin-6B methylase 2	H	Contig6	Nwi0207	COG2242	35	0.005
Precorrin-6B methylase 2	H	Contig6	Nwi0491	COG2242	38	0.001
Precorrin-6B methylase 2	H	Contig6	Nwi0586	COG2242	36	0.003
Precorrin-6B methylase 2	H	Contig6	Nwi0604	COG2242	37	0.001
Precorrin-6B methylase 2	H	Contig6	Nwi0650	COG2242	36	0.003
Precorrin-6B methylase 2	H	Contig6	Nwi0696	COG2242	42	3e-05
Precorrin-6B methylase 2	H	Contig6	Nwi1682	COG2242	38	8e-04
Precorrin-6B methylase 2	H	Contig6	Nwi1773	COG2242	53	1e-08
Precorrin-6B methylase 2	H	Contig6	Nwi1780	COG2242	46	2e-06
Precorrin-6B methylase 2	H	Contig6	Nwi1894	COG2242	39	4e-04
Precorrin-6B methylase 2	H	Contig6	Nwi1896	COG2242	38	8e-04
Precorrin-6B methylase 2	H	Contig6	Nwi2144	COG2242	40	4e-04
Precorrin-6B methylase 2	H	Contig6	Nwi2409	COG2242	35	0.004
Precorrin-6B methylase 2	H	Contig6	Nwi2481	COG2242	38	8e-04
Precorrin-6B methylase 2	H	Contig6	Nwi2522	COG2242	44	1e-05
Precorrin-6B methylase 2	H	Contig6	Nwi2590	COG2242	37	0.002

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5 6-dimethylbenzimidazole phosphoribosyltransferase)	H	Contig6	Nwi0404	COG4547	719	0.0

COBALAMIN BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Uroporphyrinogen-III methylase	H	Contig6	Nwi0115	COG0007	44	2e-05
Uroporphyrinogen-III methylase	H	Contig6	Nwi2762	COG0007	246	2e-66

COENZYME A BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Dephospho-CoA kinase	H	Contig6	Nwi0104	COG0237	168	2e-43
Ketol-acid reductoisomerase	H	Contig6	Nwi0582	COG0059	36	0.003
Ketol-acid reductoisomerase	H	Contig6	Nwi2341	COG0059	537	1.0e-154
Ketol-acid reductoisomerase	H	Contig6	Nwi2377	COG0059	36	0.005
Ketopantoate hydroxymethyltransferase	H	Contig6	Nwi2024	COG0413	342	1e-95
Ketopantoate reductase	H	Contig6	Nwi0163	COG1893	220	8e-59
Ketopantoate reductase	H	Contig6	Nwi0469	COG1893	53	3e-08
Ketopantoate reductase	H	Contig6	Nwi0543	COG1893	42	9e-05
Ketopantoate reductase	H	Contig6	Nwi2380	COG1893	39	6e-04
Panthothenate kinase	H	Contig6	Nwi0120	COG1072	342	2e-95
Panthothenate synthetase	H	Contig6	Nwi1071	COG0414	39	8e-04
Panthothenate synthetase	H	Contig6	Nwi1702	COG0414	330	9e-92
Phosphopantetheine adenylyltransferase	H	Contig6	Nwi1799	COG0669	196	8e-52
Phosphopantothenoylcysteine synthetase/decarboxylase	H	Contig6	Nwi0043	COG0452	360	1.0e-100

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Coenzyme F390 synthetase	H	Contig6	Nwi0467	COG1541	44	3e-05
Coenzyme F390 synthetase	H	Contig6	Nwi2300	COG1541	60	2e-10
Coenzyme F390 synthetase	H	Contig6	Nwi2684	COG1541	50	6e-07
Coenzyme F390 synthetase	H	Contig6	Nwi2797	COG1541	51	1e-07

DEOXYXYLULOSE PATHWAY OF TERPENOID BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Deoxyxylulose-5-phosphate synthase	H	Contig6	Nwi0633	COG1154	913	0.0
Deoxyxylulose-5-phosphate synthase	H	Contig6	Nwi1817	COG1154	97	2e-21
Deoxyxylulose-5-phosphate synthase	H	Contig6	Nwi1818	COG1154	41	1e-04
Deoxyxylulose-5-phosphate synthase	H	Contig6	Nwi2734	COG1154	72	2e-13

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Dihydrofolate reductase	H	Contig6	Nwi2350	COG0262	145	2e-36
Dihydroneopterin aldolase	H	Contig6	Nwi2234	COG1539	118	1e-28
Dihydropteroate synthase	H	Contig6	Nwi2233	COG0294	246	1e-66
Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 1	H	Contig6	Nwi0038	COG1179	90	1e-19

FAD BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
3 4-dihydroxy-2-butanone 4-phosphate synthase	H	Contig6	Nwi0607	COG0108	271	6e-74
3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase	H	Contig6	Nwi2143	COG0175	41	3e-04
3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase	H	Contig6	Nwi2761	COG0175	172	3e-44
3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase	H	Contig6	Nwi2763	COG0175	160	1e-40
FAD synthase	H	Contig6	Nwi2541	COG0196	297	7e-82
GTP cyclohydrolase II	H	Contig6	Nwi0607	COG0807	109	3e-25
Pyrimidine deaminase	H	Contig6	Nwi1725	COG0117	180	1e-46
Pyrimidine deaminase	H	Contig6	Nwi2551	COG0117	84	4e-18
Pyrimidine reductase riboflavin biosynthesis	H	Contig6	Nwi1725	COG1985	179	3e-46
Riboflavin synthase alpha chain	H	Contig6	Nwi1724	COG0307	209	1e-55
Riboflavin synthase beta-chain	H	Contig6	Nwi1723	COG0054	138	2e-34

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Flavodoxin	H	Contig6	Nwi0978	COG4635	41	5e-05
Flavoprotein involved in thiazole biosynthesis	H	Contig6	Nwi0425	COG1635	39	5e-04
Flavoprotein involved in thiazole biosynthesis	H	Contig6	Nwi0489	COG1635	41	2e-04
Flavoprotein involved in thiazole biosynthesis	H	Contig6	Nwi1507	COG1635	43	5e-05
Flavoprotein involved in thiazole biosynthesis	H	Contig6	Nwi1655	COG1635	42	7e-05
Flavoprotein involved in thiazole biosynthesis	H	Contig6	Nwi1813	COG1635	38	0.002
Flavoprotein involved in thiazole biosynthesis	H	Contig6	Nwi2154	COG1635	43	6e-05
Flavoprotein involved in thiazole biosynthesis	H	Contig6	Nwi2182	COG1635	36	0.004
Flavoprotein involved in thiazole biosynthesis	H	Contig6	Nwi2327	COG1635	39	7e-04
Flavoprotein involved in thiazole biosynthesis	H	Contig6	Nwi2365	COG1635	50	4e-07
Flavoprotein involved in thiazole biosynthesis	H	Contig6	Nwi2595	COG1635	44	3e-05
Flavoprotein involved in thiazole biosynthesis	H	Contig6	Nwi2954	COG1635	43	6e-05
Folylpolyglutamate synthase	H	Contig6	Nwi0052	COG0285	374	1.0e-105
Folylpolyglutamate synthase	H	Contig6	Nwi1046	COG0285	85	1e-17
Folylpolyglutamate synthase	H	Contig6	Nwi1047	COG0285	42	8e-05
Folylpolyglutamate synthase	H	Contig6	Nwi1049	COG0285	54	3e-08
Gamma-glutamylcysteine synthetase	H	Contig6	Nwi0182	COG3572	584	1.0e-168
Geranylgeranyl pyrophosphate synthase	H	Contig6	Nwi0495	COG0142	210	1e-55
Geranylgeranyl pyrophosphate synthase	H	Contig6	Nwi2592	COG0142	281	5e-77
Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)	H	Contig6	Nwi0117	COG0189	231	6e-62
Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)	H	Contig6	Nwi0610	COG0189	59	4e-10
Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)	H	Contig6	Nwi0897	COG0189	43	3e-05
Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)	H	Contig6	Nwi1055	COG0189	39	6e-04
Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)	H	Contig6	Nwi1736	COG0189	41	3e-04
Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)	H	Contig6	Nwi1753	COG0189	53	5e-08
Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)	H	Contig6	Nwi2449	COG0189	51	7e-07
Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)	H	Contig6	Nwi2877	COG0189	47	2e-06
GTP:adenosylcobinamide-phosphate guanylyltransferase	H	Contig6	Nwi0048	COG2266	39	3e-04
GTP:adenosylcobinamide-phosphate guanylyltransferase	H	Contig6	Nwi0286	COG2266	39	3e-04
GTP:adenosylcobinamide-phosphate guanylyltransferase	H	Contig6	Nwi0545	COG2266	43	3e-05
GTP:adenosylcobinamide-phosphate guanylyltransferase	H	Contig6	Nwi0974	COG2266	49	3e-07
GTP:adenosylcobinamide-phosphate guanylyltransferase	H	Contig6	Nwi2199	COG2266	57	4e-09
GTP:adenosylcobinamide-phosphate guanylyltransferase	H	Contig6	Nwi2394	COG2266	45	6e-06
GTP cyclohydrolase I	H	Contig6	Nwi1329	COG0302	264	3e-72

HEME BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Coproporphyrinogen III oxidase and related Fe-S oxidoreductase	H	Contig6	Nwi0014	COG0635	58	2e-09
Coproporphyrinogen III oxidase and related Fe-S oxidoreductase	H	Contig6	Nwi0191	COG0635	362	1.0e-101
Coproporphyrinogen III oxidase and related Fe-S oxidoreductase	H	Contig6	Nwi2276	COG0635	41	3e-04
Coproporphyrinogen III oxidase and related Fe-S oxidoreductase	H	Contig6	Nwi2775	COG0635	52	9e-08
Coproporphyrinogen III oxidase	H	Contig6	Nwi2621	COG0408	397	1.0e-112
Delta-aminolevulinic acid dehydratase	H	Contig6	Nwi1909	COG0113	500	1.0e-143
Glutamate-1-semialdehyde aminotransferase	H	Contig6	Nwi0242	COG0001	41	1e-04
Glutamate-1-semialdehyde aminotransferase	H	Contig6	Nwi0513	COG0001	176	2e-45
Glutamate-1-semialdehyde aminotransferase	H	Contig6	Nwi0698	COG0001	198	1e-51
Glutamate-1-semialdehyde aminotransferase	H	Contig6	Nwi2263	COG0001	209	4e-55
Glutamate-1-semialdehyde aminotransferase	H	Contig6	Nwi2388	COG0001	261	6e-71
Glutamate-1-semialdehyde aminotransferase	H	Contig6	Nwi2419	COG0001	150	2e-37
Glutamate-1-semialdehyde aminotransferase	H	Contig6	Nwi2516	COG0001	187	2e-48
Glutamate-1-semialdehyde aminotransferase	H	Contig6	Nwi2537	COG0001	162	4e-41
Glutamyl-tRNA reductase	H	Contig6	Nwi0037	COG0373	38	0.001
Glutamyl-tRNA reductase	H	Contig6	Nwi1213	COG0373	47	2e-06
Glutamyl-tRNA reductase	H	Contig6	Nwi2977	COG0373	52	4e-08
Porphobilinogen deaminase	H	Contig6	Nwi0471	COG0181	344	7e-96
Protoheme ferro-lyase (ferrochelatase)	H	Contig6	Nwi0928	COG0276	358	1.0e-100
Protoporphyrinogen oxidase	H	Contig6	Nwi0063	COG1232	49	6e-07
Protoporphyrinogen oxidase	H	Contig6	Nwi0489	COG1232	57	3e-09
Protoporphyrinogen oxidase	H	Contig6	Nwi0678	COG1232	38	0.002
Protoporphyrinogen oxidase	H	Contig6	Nwi1005	COG1232	36	0.005
Protoporphyrinogen oxidase	H	Contig6	Nwi1655	COG1232	36	0.004
Protoporphyrinogen oxidase	H	Contig6	Nwi2270	COG1232	58	1e-09
Protoporphyrinogen oxidase	H	Contig6	Nwi2282	COG1232	36	0.007
Protoporphyrinogen oxidase	H	Contig6	Nwi2327	COG1232	38	0.001
Protoporphyrinogen oxidase	H	Contig6	Nwi2595	COG1232	46	7e-06
Protoporphyrinogen oxidase	H	Contig6	Nwi2954	COG1232	46	8e-06
Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	H	Contig6	Nwi2762	COG1648	139	5e-34
Uroporphyrinogen-III decarboxylase	H	Contig6	Nwi0977	COG0407	335	2e-93
Uroporphyrinogen-III synthase	H	Contig6	Nwi0472	COG1587	99	2e-22

LEUCINE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	H	Contig6	Nwi1448	COG0115	212	3e-56
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	H	Contig6	Nwi2520	COG0115	220	1e-58
Thiamine pyrophosphate-requiring protein	H	Contig6	Nwi1947	COG0028	36	0.007
Thiamine pyrophosphate-requiring protein	H	Contig6	Nwi2343	COG0028	652	0.0
Thiamine pyrophosphate-requiring protein	H	Contig6	Nwi2734	COG0028	38	0.003
Thiamine pyrophosphate-requiring protein	H	Contig6	Nwi3016	COG0028	276	4e-75

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Lipoate-protein ligase A	H	Contig6	Nwi1731	COG0095	39	4e-04
Lipoate-protein ligase B	H	Contig6	Nwi1731	COG0321	257	4e-70
Lipoate synthase	H	Contig6	Nwi0243	COG0320	36	0.005
Lipoate synthase	H	Contig6	Nwi1439	COG0320	477	1.0e-136
Membrane-associated lipoprotein involved in thiamine biosynthesis	H	Contig6	Nwi2816	COG1477	270	8e-74

MENAQUINONE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
1 4-dihydroxy-2-naphthoate octaprenyltransferase	H	Contig6	Nwi0225	COG1575	35	0.006
1 4-dihydroxy-2-naphthoate octaprenyltransferase	H	Contig6	Nwi0763	COG1575	37	0.002
1 4-dihydroxy-2-naphthoate octaprenyltransferase	H	Contig6	Nwi2562	COG1575	42	4e-05
2-succinyl-6-hydroxy-2 4-cyclohexadiene-1-carboxylate synthase	H	Contig6	Nwi2343	COG1165	78	1e-15
2-succinyl-6-hydroxy-2 4-cyclohexadiene-1-carboxylate synthase	H	Contig6	Nwi3016	COG1165	38	0.001
Dihydroxynaphthoic acid synthase	H	Contig6	Nwi0636	COG0447	85	4e-18
Dihydroxynaphthoic acid synthase	H	Contig6	Nwi2157	COG0447	48	1e-06
Dihydroxynaphthoic acid synthase	H	Contig6	Nwi2252	COG0447	136	1e-33
Dihydroxynaphthoic acid synthase	H	Contig6	Nwi2993	COG0447	55	2e-08
Isochorismate synthase	H	Contig6	Nwi0951	COG1169	141	2e-34
Isochorismate synthase	H	Contig6	Nwi2614	COG1169	118	1e-27

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Mg-chelatase subunit ChlD	H	Contig6	Nwi2202	COG1240	38	0.001
Mg-chelatase subunit ChlI	H	Contig6	Nwi0118	COG1239	70	3e-13
Mg-chelatase subunit ChlI	H	Contig6	Nwi0595	COG1239	37	0.003
Mg-chelatase subunit ChlI	H	Contig6	Nwi1447	COG1239	40	4e-04
Mg-chelatase subunit ChlI	H	Contig6	Nwi2626	COG1239	61	1e-10
Molybdenum cofactor biosynthesis enzyme	H	Contig6	Nwi1839	COG0315	205	1e-54
Molybdenum cofactor biosynthesis protein	H	Contig6	Nwi0243	COG2896	40	2e-04
Molybdenum cofactor biosynthesis protein	H	Contig6	Nwi0689	COG2896	69	5e-13
Molybdenum cofactor biosynthesis protein	H	Contig6	Nwi1219	COG2896	387	1.0e-109
Molybdenum cofactor biosynthesis protein	H	Contig6	Nwi2258	COG2896	37	0.003
Molybdenum cofactor biosynthesis protein	H	Contig6	Nwi2267	COG2896	77	2e-15
Molybdenum cofactor biosynthesis protein	H	Contig6	Nwi2600	COG2896	37	0.002
Molybdopterin biosynthesis enzyme	H	Contig6	Nwi1840	COG0303	347	6e-97
Molybdopterin biosynthesis enzyme	H	Contig6	Nwi2189	COG0303	40	1e-04
Molybdopterin biosynthesis enzyme	H	Contig6	Nwi2199	COG0303	109	3e-25
Molybdopterin biosynthesis enzyme	H	Contig6	Nwi2601	COG0303	57	1e-09
Molybdopterin biosynthesis protein	H	Contig6	Nwi2189	COG0521	52	3e-08
Molybdopterin biosynthesis protein	H	Contig6	Nwi2199	COG0521	38	0.002
Molybdopterin biosynthesis protein	H	Contig6	Nwi2601	COG0521	202	2e-53
Molybdopterin converting factor large subunit	H	Contig6	Nwi2523	COG0314	153	8e-39
Molybdopterin converting factor small subunit	H	Contig6	Nwi2524	COG1977	84	2e-18
Molybdopterin-guanine dinucleotide biosynthesis protein A	H	Contig6	Nwi0048	COG0746	40	1e-04
Molybdopterin-guanine dinucleotide biosynthesis protein A	H	Contig6	Nwi0545	COG0746	36	0.004
Molybdopterin-guanine dinucleotide biosynthesis protein A	H	Contig6	Nwi0645	COG0746	37	0.001
Molybdopterin-guanine dinucleotide biosynthesis protein A	H	Contig6	Nwi0974	COG0746	151	5e-38
Molybdopterin-guanine dinucleotide biosynthesis protein A	H	Contig6	Nwi1442	COG0746	36	0.003
Molybdopterin-guanine dinucleotide biosynthesis protein A	H	Contig6	Nwi1784	COG0746	49	7e-07
Molybdopterin-guanine dinucleotide biosynthesis protein A	H	Contig6	Nwi2199	COG0746	70	6e-13
Molybdopterin-guanine dinucleotide biosynthesis protein	H	Contig6	Nwi2240	COG1763	36	0.005

NAD BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Aspartate oxidase	H	Contig6	Nwi0678	COG0029	163	3e-41
Aspartate oxidase	H	Contig6	Nwi1223	COG0029	36	0.006
Aspartate oxidase	H	Contig6	Nwi1813	COG0029	38	0.002
Aspartate oxidase	H	Contig6	Nwi2182	COG0029	45	1e-05
Aspartate oxidase	H	Contig6	Nwi2425	COG0029	549	1.0e-157
Aspartate oxidase	H	Contig6	Nwi2800	COG0029	357	2e-99
NAD synthase	H	Contig6	Nwi0603	COG0171	38	0.001
NAD synthase	H	Contig6	Nwi1225	COG0171	244	1e-65
NAD synthase	H	Contig6	Nwi2143	COG0171	43	5e-05
Nicotinamide mononucleotide adenylyltransferase	H	Contig6	Nwi1799	COG1056	41	4e-05
Nicotinate-nucleotide pyrophosphorylase	H	Contig6	Nwi2426	COG0157	350	6e-98
Nicotinic acid mononucleotide adenylyltransferase	H	Contig6	Nwi0445	COG1057	140	8e-35
Nicotinic acid mononucleotide adenylyltransferase	H	Contig6	Nwi1799	COG1057	51	6e-08
Quinolinate synthase	H	Contig6	Nwi2424	COG0379	410	1.0e-116

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Outer membrane cobalamin receptor protein	H	Contig6	Nwi0253	COG4206	46	2e-06
Outer membrane cobalamin receptor protein	H	Contig6	Nwi0658	COG4206	56	6e-09
Outer membrane cobalamin receptor protein	H	Contig6	Nwi0661	COG4206	58	1e-09
Outer membrane cobalamin receptor protein	H	Contig6	Nwi0700	COG4206	57	6e-09
Outer membrane cobalamin receptor protein	H	Contig6	Nwi0725	COG4206	66	8e-12
Outer membrane cobalamin receptor protein	H	Contig6	Nwi0726	COG4206	41	5e-05
Outer membrane cobalamin receptor protein	H	Contig6	Nwi0941	COG4206	113	4e-26
Outer membrane cobalamin receptor protein	H	Contig6	Nwi1338	COG4206	62	1e-10
Outer membrane cobalamin receptor protein	H	Contig6	Nwi1732	COG4206	58	4e-09
Outer membrane cobalamin receptor protein	H	Contig6	Nwi1868	COG4206	59	2e-09
Outer membrane cobalamin receptor protein	H	Contig6	Nwi2049	COG4206	43	8e-05
Outer membrane cobalamin receptor protein	H	Contig6	Nwi2072	COG4206	70	7e-13
Outer membrane cobalamin receptor protein	H	Contig6	Nwi2076	COG4206	59	7e-10
Outer membrane cobalamin receptor protein	H	Contig6	Nwi2219	COG4206	292	7e-80
Outer membrane cobalamin receptor protein	H	Contig6	Nwi2294	COG4206	45	2e-05
Outer membrane cobalamin receptor protein	H	Contig6	Nwi2296	COG4206	63	7e-11
Outer membrane cobalamin receptor protein	H	Contig6	Nwi2318	COG4206	61	4e-10
Outer membrane cobalamin receptor protein	H	Contig6	Nwi2631	COG4206	63	7e-11
Outer membrane cobalamin receptor protein	H	Contig6	Nwi2881	COG4206	118	2e-27
Outer membrane cobalamin receptor protein	H	Contig6	Nwi2902	COG4206	74	3e-14
Outer membrane cobalamin receptor protein	H	Contig6	Nwi3043	COG4206	116	8e-27
Outer membrane cobalamin receptor protein	H	Contig6	Nwi3051	COG4206	80	7e-16
Precorrin-4 methylase	H	Contig6	Nwi2762	COG2875	141	1e-34
Predicted glutamine amidotransferase involved in pyridoxine biosynthesis	H	Contig6	Nwi0124	COG0311	34	0.007
Predicted glutamine amidotransferase involved in pyridoxine biosynthesis	H	Contig6	Nwi1306	COG0311	34	0.009
Predicted glutamine amidotransferase involved in pyridoxine biosynthesis	H	Contig6	Nwi2391	COG0311	43	2e-05
Pterin-4a-carbinolamine dehydratase	H	Contig6	Nwi1979	COG2154	36	6e-04
Pterin-4a-carbinolamine dehydratase	H	Contig6	Nwi2809	COG2154	118	9e-29

PYRIDOXAL PHOSPHATE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Lactate dehydrogenase and related dehydrogenase	H	Contig6	Nwi0037	COG1052	333	8e-93
Lactate dehydrogenase and related dehydrogenase	H	Contig6	Nwi2341	COG1052	36	0.005
Lactate dehydrogenase and related dehydrogenase	H	Contig6	Nwi2377	COG1052	39	0.001
Lactate dehydrogenase and related dehydrogenase	H	Contig6	Nwi2968	COG1052	272	4e-74
Phosphoserine aminotransferase	H	Contig6	Nwi2413	COG1932	57	2e-09
Phosphoserine aminotransferase	H	Contig6	Nwi2969	COG1932	364	1.0e-102
Pyridoxal phosphate biosynthesis protein	H	Contig6	Nwi1681	COG1995	356	1e-99
Pyridoxal phosphate biosynthesis protein	H	Contig6	Nwi1921	COG0854	284	5e-78
Pyridoxal phosphate biosynthesis protein	H	Contig6	Nwi2795	COG1995	36	0.006
Pyridoxal/pyridoxine/pyridoxamine kinase	H	Contig6	Nwi0218	COG2240	40	2e-04
Pyridoxal/pyridoxine/pyridoxamine kinase	H	Contig6	Nwi1071	COG2240	38	0.002
Pyridoxal/pyridoxine/pyridoxamine kinase	H	Contig6	Nwi1082	COG2240	64	8e-12
Pyridoxamine-phosphate oxidase	H	Contig6	Nwi0622	COG0259	273	6e-75
Pyridoxine biosynthesis enzyme	H	Contig6	Nwi1443	COG0214	38	0.001
Pyridoxine biosynthesis enzyme	H	Contig6	Nwi2817	COG0214	38	0.001

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C	H	Contig6	Nwi0691	COG5424	222	3e-59
Pyruvate decarboxylase	H	Contig6	Nwi2343	COG3961	172	5e-44
Pyruvate decarboxylase	H	Contig6	Nwi3016	COG3961	106	3e-24
S-adenosylhomocysteine hydrolase	H	Contig6	Nwi2341	COG0499	45	1e-05
S-adenosylhomocysteine hydrolase	H	Contig6	Nwi2377	COG0499	617	1.0e-178
S-adenosylhomocysteine hydrolase	H	Contig6	Nwi2968	COG0499	37	0.003
S-adenosylmethionine synthetase	H	Contig6	Nwi2378	COG0192	561	1.0e-161

THIAMINE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2	H	Contig6	Nwi0038	COG0476	251	4e-68
Hydroxyethylthiazole kinase sugar kinase family	H	Contig6	Nwi1902	COG2145	41	3e-04
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	H	Contig6	Nwi1071	COG0351	45	1e-05
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	H	Contig6	Nwi1082	COG0351	313	7e-87
Sulfur transfer protein involved in thiamine biosynthesis	H	Contig6	Nwi2465	COG2104	68	1e-13
Thiamine biosynthesis ATP pyrophosphatase	H	Contig6	Nwi0603	COG0301	36	0.003
Thiamine biosynthesis ATP pyrophosphatase	H	Contig6	Nwi2143	COG0301	41	2e-04
Thiamine biosynthesis protein ThiC	H	Contig6	Nwi2468	COG0422	733	0.0
Thiamine biosynthesis protein ThiH	H	Contig6	Nwi0243	COG1060	72	4e-14
Thiamine biosynthesis protein ThiH	H	Contig6	Nwi1219	COG1060	36	0.003
Thiamine biosynthesis protein ThiH	H	Contig6	Nwi2600	COG1060	41	1e-04
Thiamine monophosphate kinase	H	Contig6	Nwi1308	COG0611	50	6e-07
Thiamine monophosphate kinase	H	Contig6	Nwi1597	COG0611	51	1e-07
Thiamine monophosphate kinase	H	Contig6	Nwi1721	COG0611	257	8e-70
Thiamine monophosphate synthase	H	Contig6	Nwi1862	COG0352	36	0.003
Thiamine monophosphate synthase	H	Contig6	Nwi2467	COG0352	173	7e-45
Thiamine monophosphate synthase	H	Contig6	Nwi2738	COG0352	73	2e-14

TRYPTOPHAN BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Anthranilate/para-aminobenzoate synthase component I	H	Contig6	Nwi0951	COG0147	383	1.0e-107
Anthranilate/para-aminobenzoate synthase component I	H	Contig6	Nwi2614	COG0147	330	2e-91
Anthranilate/para-aminobenzoate synthase component II	H	Contig6	Nwi0124	COG0512	48	6e-07
Anthranilate/para-aminobenzoate synthase component II	H	Contig6	Nwi0951	COG0512	227	2e-60
Anthranilate/para-aminobenzoate synthase component II	H	Contig6	Nwi2143	COG0512	89	9e-19
Anthranilate/para-aminobenzoate synthase component II	H	Contig6	Nwi2391	COG0512	43	2e-05
Anthranilate/para-aminobenzoate synthase component II	H	Contig6	Nwi2446	COG0512	100	3e-22
Anthranilate/para-aminobenzoate synthase component II	H	Contig6	Nwi2614	COG0512	226	4e-60

UBIQUINONE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig6	Nwi0041	COG2227	54	1e-08
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig6	Nwi0374	COG2227	36	0.003
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig6	Nwi0376	COG2227	36	0.004
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig6	Nwi0381	COG2227	276	2e-75
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig6	Nwi0491	COG2227	58	7e-10
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig6	Nwi0534	COG2227	39	3e-04
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig6	Nwi0586	COG2227	47	9e-07
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig6	Nwi0604	COG2227	64	8e-12
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig6	Nwi0650	COG2227	44	1e-05
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig6	Nwi0696	COG2227	62	3e-11
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig6	Nwi1896	COG2227	61	1e-10
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig6	Nwi2012	COG2227	66	3e-12
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig6	Nwi2367	COG2227	42	6e-05
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig6	Nwi2409	COG2227	57	1e-09
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig6	Nwi2522	COG2227	36	0.006
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi0079	COG0654	246	2e-66
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi0097	COG0654	43	7e-05
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi0425	COG0654	38	0.001
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi0489	COG0654	37	0.003
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi0543	COG0654	36	0.004
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi0889	COG0654	38	0.001
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi1005	COG0654	37	0.002
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi1089	COG0654	42	5e-05
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi1352	COG0654	39	1e-04
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi1353	COG0654	35	0.001
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi1354	COG0654	49	7e-08
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi1507	COG0654	215	4e-57
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi1655	COG0654	176	4e-45
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi1764	COG0654	36	0.005
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi1813	COG0654	42	1e-04
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi2154	COG0654	37	0.002
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi2182	COG0654	160	2e-40
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi2282	COG0654	38	0.002
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi2327	COG0654	176	2e-45
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi2365	COG0654	40	3e-04
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi2464	COG0654	37	0.002
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi2595	COG0654	59	9e-10
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig6	Nwi2954	COG0654	43	4e-05
2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase	H	Contig6	Nwi0590	COG0543	42	1e-04
2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase	H	Contig6	Nwi1063	COG0543	34	0.009
3-polyprenyl-4-hydroxybenzoate decarboxylase	H	Contig6	Nwi0043	COG0163	45	1e-05
4-hydroxybenzoate polyprenyltransferase and related prenyltransferase	H	Contig6	Nwi0225	COG0382	66	3e-12
4-hydroxybenzoate polyprenyltransferase and related prenyltransferase	H	Contig6	Nwi0763	COG0382	71	1e-13
4-hydroxybenzoate polyprenyltransferase and related prenyltransferase	H	Contig6	Nwi2562	COG0382	172	2e-44
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi0041	COG2226	282	2e-77
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi0156	COG2226	39	6e-04
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi0374	COG2226	44	1e-05
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi0376	COG2226	37	0.002
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi0381	COG2226	47	1e-06
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi0491	COG2226	73	3e-14
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi0534	COG2226	45	3e-06
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi0586	COG2226	53	2e-08
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi0604	COG2226	92	3e-20
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi0650	COG2226	53	2e-08
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi0696	COG2226	113	9e-27
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi1043	COG2226	37	0.002
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi1773	COG2226	44	6e-06
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi1896	COG2226	88	5e-19
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi2012	COG2226	47	2e-06
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi2144	COG2226	45	1e-05
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi2149	COG2226	58	8e-10
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi2367	COG2226	38	8e-04
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi2409	COG2226	47	1e-06
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi2448	COG2226	41	8e-05
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi2481	COG2226	68	6e-13
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi2522	COG2226	46	4e-06
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig6	Nwi2609	COG2226	35	0.009

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Uncharacterized protein of heme biosynthesis	H	Contig6	Nwi0474	COG3071	104	2e-23
Uncharacterized protein of heme biosynthesis	H	Contig6	Nwi1742	COG3071	36	0.007

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