Nucleotide Transport and Metabolism

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase	F	Contig10	Noc2931	COG0737	36	0.006
Adenine deaminase	F	Contig10	Noc0024	COG1001	37	0.005
Adenine deaminase	F	Contig10	Noc0364	COG1001	42	7e-05
Adenine deaminase	F	Contig10	Noc0420	COG1001	42	1e-04
Adenine deaminase	F	Contig10	Noc2295	COG1001	43	3e-05
Adenine deaminase	F	Contig10	Noc2880	COG1001	63	7e-11
ADP-ribose pyrophosphatase	F	Contig10	Noc0193	COG1051	50	6e-08
ADP-ribose pyrophosphatase	F	Contig10	Noc0306	COG1051	62	7e-11
ADP-ribose pyrophosphatase	F	Contig10	Noc1415	COG1051	41	4e-05
ADP-ribose pyrophosphatase	F	Contig10	Noc2018	COG1051	50	8e-08
ADP-ribose pyrophosphatase	F	Contig10	Noc2420	COG1051	45	4e-06
ADP-ribose pyrophosphatase	F	Contig10	Noc2512	COG1051	52	2e-08
ADP-ribose pyrophosphatase	F	Contig10	Noc2643	COG1051	108	2e-25
Cytosine/adenosine deaminase	F	Contig10	Noc1166	COG0590	121	3e-29
Cytosine/adenosine deaminase	F	Contig10	Noc1211	COG0590	90	5e-20
Cytosine/adenosine deaminase	F	Contig10	Noc2025	COG0590	69	5e-13
Cytosine/adenosine deaminase	F	Contig10	Noc2603	COG0590	188	2e-49
Deoxycytidylate deaminase	F	Contig10	Noc1166	COG2131	43	1e-05
Deoxycytidylate deaminase	F	Contig10	Noc2025	COG2131	67	3e-12
Deoxycytidylate deaminase	F	Contig10	Noc2603	COG2131	57	9e-10
Deoxynucleoside kinase	F	Contig10	Noc0179	COG1428	36	0.002
Deoxynucleoside kinase	F	Contig10	Noc2877	COG1428	36	0.001
Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase	F	Contig10	Noc3057	COG0537	109	4e-26
DNA/RNA endonuclease G NUC1	F	Contig10	Noc1834	COG1864	117	8e-28
Exopolyphosphatase	F	Contig10	Noc2394	COG0248	430	1.0e-121
Guanylate kinase	F	Contig10	Noc1212	COG0194	243	6e-66
Guanylate kinase	F	Contig10	Noc1836	COG0194	34	0.006
Orotate phosphoribosyltransferase homologs	F	Contig10	Noc0169	COG0856	40	1e-04
Orotate phosphoribosyltransferase homologs	F	Contig10	Noc0514	COG0856	36	0.004
Orotate phosphoribosyltransferase homologs	F	Contig10	Noc0983	COG0856	41	1e-04
Orotate phosphoribosyltransferase homologs	F	Contig10	Noc1671	COG0856	45	2e-05
Orotate phosphoribosyltransferase homologs	F	Contig10	Noc2998	COG0856	52	4e-08
Predicted nucleotide kinase	F	Contig10	Noc0179	COG4088	34	0.008
Predicted nucleotide kinase	F	Contig10	Noc2877	COG1618	39	2e-04

PURINE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Adenylosuccinate lyase	F	Contig10	Noc0501	COG0015	149	5e-37
Adenylosuccinate lyase	F	Contig10	Noc1627	COG0015	131	8e-32
Adenylosuccinate lyase	F	Contig10	Noc2106	COG0015	368	1.0e-103
Adenylosuccinate synthase	F	Contig10	Noc2585	COG0104	621	1.0e-179
AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)	F	Contig10	Noc1048	COG0138	745	0.0
AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)	F	Contig10	Noc2572	COG0138	43	9e-05
Folate-dependent phosphoribosylglycinamide formyltransferase PurN	F	Contig10	Noc1181	COG0299	269	1e-73
Folate-dependent phosphoribosylglycinamide formyltransferase PurN	F	Contig10	Noc1789	COG0299	130	1e-31
Folate-dependent phosphoribosylglycinamide formyltransferase PurN	F	Contig10	Noc3015	COG0299	88	1e-18
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	Contig10	Noc0260	COG0027	39	7e-04
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	Contig10	Noc2572	COG0027	58	3e-09
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	Contig10	Noc2827	COG0027	39	5e-04
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	Contig10	Noc2858	COG0027	40	2e-04
Glutamine phosphoribosylpyrophosphate amidotransferase	F	Contig10	Noc0777	COG0034	84	4e-17
Glutamine phosphoribosylpyrophosphate amidotransferase	F	Contig10	Noc0983	COG0034	43	4e-05
Glutamine phosphoribosylpyrophosphate amidotransferase	F	Contig10	Noc1389	COG0034	45	5e-06
Glutamine phosphoribosylpyrophosphate amidotransferase	F	Contig10	Noc1604	COG0034	47	1e-05
Glutamine phosphoribosylpyrophosphate amidotransferase	F	Contig10	Noc1671	COG0034	624	1.0e-180
Glutamine phosphoribosylpyrophosphate amidotransferase	F	Contig10	Noc1975	COG0034	71	3e-13
Glutamine phosphoribosylpyrophosphate amidotransferase	F	Contig10	Noc2478	COG0034	68	2e-12
Glutamine phosphoribosylpyrophosphate amidotransferase	F	Contig10	Noc2998	COG0034	36	0.002
Glutamine phosphoribosylpyrophosphate amidotransferase	F	Contig10	Noc3071	COG0034	126	5e-30
GMP synthase - Glutamine amidotransferase domain	F	Contig10	Noc0614	COG0518	213	3e-56
GMP synthase - Glutamine amidotransferase domain	F	Contig10	Noc2237	COG0518	172	2e-44
GMP synthase - Glutamine amidotransferase domain	F	Contig10	Noc2495	COG0518	85	4e-18
GMP synthase - Glutamine amidotransferase domain	F	Contig10	Noc2573	COG0518	72	7e-14
GMP synthase - Glutamine amidotransferase domain	F	Contig10	Noc2703	COG0518	39	6e-04
GMP synthase - Glutamine amidotransferase domain	F	Contig10	Noc3052	COG0518	49	2e-07
GMP synthase PP-ATPase domain/subunit	F	Contig10	Noc0614	COG0519	532	1.0e-152
GMP synthase PP-ATPase domain/subunit	F	Contig10	Noc2040	COG0519	39	6e-04
IMP dehydrogenase/GMP reductase	F	Contig10	Noc0613	COG0516	133	2e-32
Phosphoribosylamine-glycine ligase	F	Contig10	Noc0713	COG0151	40	3e-04
Phosphoribosylamine-glycine ligase	F	Contig10	Noc1051	COG0151	56	4e-09
Phosphoribosylamine-glycine ligase	F	Contig10	Noc2222	COG0151	41	1e-04
Phosphoribosylamine-glycine ligase	F	Contig10	Noc2572	COG0151	60	1e-09
Phosphoribosylamine-glycine ligase	F	Contig10	Noc2827	COG0151	581	1.0e-167
Phosphoribosylaminoimidazole (AIR) synthetase	F	Contig10	Noc0804	COG0150	42	4e-05
Phosphoribosylaminoimidazole (AIR) synthetase	F	Contig10	Noc1182	COG0150	498	1.0e-142
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	Contig10	Noc0260	COG0026	45	8e-06
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	Contig10	Noc1051	COG0026	61	2e-10
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	Contig10	Noc1549	COG0026	38	7e-04
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	Contig10	Noc2572	COG0026	56	1e-08
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	Contig10	Noc2827	COG0026	53	3e-08
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	Contig10	Noc2858	COG0026	43	3e-05
Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase	F	Contig10	Noc2522	COG0152	292	1e-80
Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	F	Contig10	Noc3009	COG0041	181	3e-47
Phosphoribosylformylglycinamidine (FGAM) synthase glutamine amidotransferase domain	F	Contig10	Noc1907	COG0047	255	1e-68
Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain	F	Contig10	Noc0804	COG0046	38	7e-04
Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain	F	Contig10	Noc1182	COG0046	41	1e-04
Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain	F	Contig10	Noc1907	COG0046	701	0.0
Phosphoribosylpyrophosphate synthetase	F	Contig10	Noc0169	COG0462	37	8e-04
Phosphoribosylpyrophosphate synthetase	F	Contig10	Noc0514	COG0462	408	1.0e-115
Phosphoribosylpyrophosphate synthetase	F	Contig10	Noc0983	COG0462	269	2e-73
Phosphoribosylpyrophosphate synthetase	F	Contig10	Noc1671	COG0462	41	2e-04
Phosphoribosylpyrophosphate synthetase	F	Contig10	Noc2102	COG0462	36	0.002
Phosphoribosylpyrophosphate synthetase	F	Contig10	Noc2998	COG0462	38	5e-04

PURINE SALVAGE

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	Contig10	Noc0169	COG0503	186	1e-48
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	Contig10	Noc0456	COG0503	35	0.003
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	Contig10	Noc0514	COG0503	45	7e-06
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	Contig10	Noc1671	COG0503	38	0.001
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	Contig10	Noc2102	COG0503	42	4e-05
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	Contig10	Noc2998	COG0503	54	1e-08
Formyltetrahydrofolate hydrolase	F	Contig10	Noc1181	COG0788	133	1e-32
Formyltetrahydrofolate hydrolase	F	Contig10	Noc1789	COG0788	404	1.0e-114
Formyltetrahydrofolate hydrolase	F	Contig10	Noc3015	COG0788	55	7e-09
Hypoxanthine-guanine phosphoribosyltransferase	F	Contig10	Noc0366	COG0634	56	2e-09
Hypoxanthine-guanine phosphoribosyltransferase	F	Contig10	Noc0456	COG0634	169	9e-44
Hypoxanthine-guanine phosphoribosyltransferase	F	Contig10	Noc0983	COG0634	44	2e-05
Hypoxanthine-guanine phosphoribosyltransferase	F	Contig10	Noc1671	COG0634	36	0.005
Purine nucleoside phosphorylase	F	Contig10	Noc0457	COG0005	221	4e-59

PYRIMIDINE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Adenylate kinase and related kinase	F	Contig10	Noc0179	COG0563	43	2e-05
Adenylate kinase and related kinase	F	Contig10	Noc1818	COG0563	36	0.007
Adenylate kinase and related kinase	F	Contig10	Noc2157	COG0563	36	0.005
Adenylate kinase and related kinase	F	Contig10	Noc2847	COG0563	177	5e-46
Aspartate carbamoyltransferase catalytic chain	F	Contig10	Noc0365	COG0540	359	1.0e-100
Aspartate carbamoyltransferase catalytic chain	F	Contig10	Noc0778	COG0540	200	1e-52
Aspartate carbamoyltransferase catalytic chain	F	Contig10	Noc2430	COG0540	161	4e-41
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	Contig10	Noc0259	COG0458	36	0.003
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	Contig10	Noc1051	COG0458	85	2e-17
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	Contig10	Noc1549	COG0458	44	9e-06
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	Contig10	Noc2222	COG0458	43	3e-05
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	Contig10	Noc2572	COG0458	583	1.0e-167
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	Contig10	Noc2827	COG0458	43	5e-05
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	Contig10	Noc2858	COG0458	54	1e-08
Carbamoylphosphate synthase small subunit	F	Contig10	Noc0614	COG0505	62	1e-10
Carbamoylphosphate synthase small subunit	F	Contig10	Noc0850	COG0505	42	7e-05
Carbamoylphosphate synthase small subunit	F	Contig10	Noc2237	COG0505	34	0.009
Carbamoylphosphate synthase small subunit	F	Contig10	Noc2495	COG0505	86	2e-18
Carbamoylphosphate synthase small subunit	F	Contig10	Noc2573	COG0505	549	1.0e-157
CTP synthase (UTP-ammonia lyase)	F	Contig10	Noc0850	COG0504	872	0.0
CTP synthase (UTP-ammonia lyase)	F	Contig10	Noc2573	COG0504	41	1e-04
Cytidylate kinase	F	Contig10	Noc0179	COG1102	57	1e-09
Cytidylate kinase	F	Contig10	Noc0179	COG0283	262	1e-71
Cytidylate kinase	F	Contig10	Noc0252	COG1102	42	3e-05
Cytidylate kinase	F	Contig10	Noc2847	COG1102	38	8e-04
Dihydroorotase and related cyclic amidohydrolase	F	Contig10	Noc0024	COG0044	44	3e-05
Dihydroorotase and related cyclic amidohydrolase	F	Contig10	Noc0364	COG0044	376	1.0e-105
Dihydroorotase and related cyclic amidohydrolase	F	Contig10	Noc0420	COG0044	38	0.002
Dihydroorotase and related cyclic amidohydrolase	F	Contig10	Noc2521	COG0044	67	2e-12
Dihydroorotase and related cyclic amidohydrolase	F	Contig10	Noc2880	COG0044	72	9e-14
Dihydroorotase	F	Contig10	Noc0364	COG0418	37	0.002
Dihydroorotase	F	Contig10	Noc2521	COG0418	527	1.0e-151
Dihydroorotate dehydrogenase	F	Contig10	Noc0604	COG0167	42	4e-05
Dihydroorotate dehydrogenase	F	Contig10	Noc0613	COG0167	39	0.001
Dihydroorotate dehydrogenase	F	Contig10	Noc2822	COG0167	260	1e-70
Dihydroorotate dehydrogenase	F	Contig10	Noc2960	COG0167	42	6e-05
Orotate phosphoribosyltransferase	F	Contig10	Noc0169	COG0461	42	4e-05
Orotate phosphoribosyltransferase	F	Contig10	Noc0514	COG0461	38	0.002
Orotate phosphoribosyltransferase	F	Contig10	Noc0983	COG0461	36	0.004
Orotate phosphoribosyltransferase	F	Contig10	Noc2102	COG0461	40	1e-04
Orotate phosphoribosyltransferase	F	Contig10	Noc2998	COG0461	189	1e-49
Orotidine-5'-phosphate decarboxylase	F	Contig10	Noc2353	COG0284	247	7e-67
Uridylate kinase	F	Contig10	Noc0810	COG0528	314	5e-87
Uridylate kinase	F	Contig10	Noc0927	COG0528	64	1e-11
Uridylate kinase	F	Contig10	Noc3036	COG0528	63	3e-11

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	F	Contig10	Noc0169	COG2065	35	0.005
Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	F	Contig10	Noc0366	COG2065	164	4e-42
Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	F	Contig10	Noc0456	COG2065	39	3e-04

PYRIMIDINE SALVAGE

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Cytosine deaminase and related metal-dependent hydrolase	F	Contig10	Noc0364	COG0402	46	5e-06
Cytosine deaminase and related metal-dependent hydrolase	F	Contig10	Noc0420	COG0402	55	1e-08
Cytosine deaminase and related metal-dependent hydrolase	F	Contig10	Noc2295	COG0402	329	3e-91
Cytosine deaminase and related metal-dependent hydrolase	F	Contig10	Noc2880	COG0402	49	8e-07
Nucleoside phosphorylase	F	Contig10	Noc1319	COG0775	62	3e-11
Purine-nucleoside phosphorylase	F	Contig10	Noc1319	COG0813	34	0.007
Thymidine phosphorylase	F	Contig10	Noc2496	COG0213	59	3e-10
Uracil phosphoribosyltransferase	F	Contig10	Noc0366	COG0035	38	5e-04
Uridine kinase	F	Contig10	Noc0179	COG0572	34	0.009
Uridine kinase	F	Contig10	Noc0494	COG0572	45	9e-06
Uridine kinase	F	Contig10	Noc2826	COG0572	59	3e-10
Uridine kinase	F	Contig10	Noc2877	COG0572	38	5e-04

THIAMINE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Uncharacterized protein of thiazole biosynthesis	F	Contig10	Noc1633	COG2022	373	1.0e-105

THYMIDYLATE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Deoxycytidine deaminase	F	Contig10	Noc1180	COG0717	215	1e-57
Deoxycytidine deaminase	F	Contig10	Noc2993	COG0717	46	1e-06
dUTPase	F	Contig10	Noc2993	COG0756	190	4e-50
Nucleoside diphosphate kinase	F	Contig10	Noc0899	COG0105	204	2e-54
Oxygen-sensitive ribonucleoside-triphosphate reductase	F	Contig10	Noc2527	COG1328	57	9e-09
Ribonucleotide reductase alpha subunit	F	Contig10	Noc2527	COG0209	453	1.0e-128
Ribonucleotide reductase beta subunit	F	Contig10	Noc2528	COG0208	342	2e-95
Thymidylate kinase	F	Contig10	Noc1210	COG0125	36	0.008
Thymidylate kinase	F	Contig10	Noc1660	COG0125	210	6e-56
Thymidylate synthase	F	Contig10	Noc0234	COG0207	378	1.0e-106

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Uridine phosphorylase	F	Contig10	Noc1319	COG2820	35	0.006
Xanthine/uracil permease	F	Contig10	Noc1626	COG2233	41	3e-04
Xanthosine triphosphate pyrophosphatase	F	Contig10	Noc2443	COG0127	227	5e-61

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