Lipid Metabolism

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
1-acyl-sn-glycerol-3-phosphate acyltransferase	I	Contig12	NmulA0207	COG0204	89	3e-19
1-acyl-sn-glycerol-3-phosphate acyltransferase	I	Contig12	NmulA0548	COG0204	110	1e-25
3-hydroxy-3-methylglutaryl CoA synthase	I	Contig12	NmulA1072	COG3425	96	2e-21
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig12	NmulA0172	COG2084	303	1e-83
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig12	NmulA0270	COG2084	46	4e-06
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig12	NmulA0428	COG2084	37	0.002
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig12	NmulA0472	COG2084	48	9e-07
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig12	NmulA0581	COG2084	35	0.006
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig12	NmulA1623	COG2084	115	4e-27
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig12	NmulA2191	COG2084	37	0.002
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig12	NmulA2195	COG2084	38	0.001
3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	I	Contig12	NmulA0667	COG0764	179	6e-47
Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	I	Contig12	NmulA1810	COG4799	83	4e-17
Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	I	Contig12	NmulA1910	COG4799	68	8e-13
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig12	NmulA0134	COG4770	44	3e-05
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig12	NmulA0359	COG4770	47	2e-06
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig12	NmulA0479	COG4770	67	7e-12
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig12	NmulA0515	COG4770	46	1e-05
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig12	NmulA0611	COG4770	38	0.001
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig12	NmulA0943	COG4770	564	1.0e-161
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig12	NmulA2250	COG4770	48	2e-06
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig12	NmulA2251	COG4770	43	6e-05
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig12	NmulA2491	COG4770	54	1e-08
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig12	NmulA2752	COG4770	594	1.0e-171
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig12	NmulA2753	COG4770	58	2e-10
Acyl carrier protein phosphodiesterase	I	Contig12	NmulA1470	COG1182	37	0.001
Acyl carrier protein phosphodiesterase	I	Contig12	NmulA1574	COG1182	42	3e-05
Acyl-CoA dehydrogenase	I	Contig12	NmulA0094	COG1960	201	1e-52
Acyl-CoA dehydrogenase	I	Contig12	NmulA0967	COG1960	203	3e-53
Acyl-CoA hydrolase	I	Contig12	NmulA0096	COG1607	140	4e-35
Acyl-CoA hydrolase	I	Contig12	NmulA2718	COG1607	33	0.006
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig12	NmulA0095	COG0365	156	6e-39
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig12	NmulA0231	COG0365	159	6e-40
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig12	NmulA0291	COG0365	47	2e-06
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig12	NmulA0968	COG0365	204	1e-53
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig12	NmulA1417	COG0365	154	2e-38
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig12	NmulA1829	COG0365	205	5e-53
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig12	NmulA1830	COG0365	213	5e-56
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig12	NmulA1832	COG0365	195	2e-50
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig12	NmulA1867	COG0365	310	1e-85
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig12	NmulA1868	COG0365	336	1e-93
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig12	NmulA2670	COG0365	250	1e-67
Acyl dehydratase	I	Contig12	NmulA0620	COG2030	106	9e-25
Carboxylesterase type B	I	Contig12	NmulA1827	COG2272	48	8e-07
Carboxylesterase type B	I	Contig12	NmulA2303	COG2272	41	2e-04
CDP-diglyceride synthetase	I	Contig12	NmulA0662	COG0575	105	4e-24
Cytidylyltransferase	I	Contig12	NmulA1792	COG0615	69	1e-12
Cytidylyltransferase	I	Contig12	NmulA2734	COG0615	43	1e-05

DEOXYXYLULOSE PATHWAY OF TERPENOID BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
1-deoxy-D-xylulose 5-phosphate reductoisomerase	I	Contig12	NmulA0663	COG0743	535	1.0e-153
1-deoxy-D-xylulose 5-phosphate reductoisomerase	I	Contig12	NmulA1551	COG0743	45	1e-05
2C-methyl-D-erythritol 2 4-cyclodiphosphate synthase	I	Contig12	NmulA2126	COG0245	225	1e-60
4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase	I	Contig12	NmulA0588	COG1947	302	1e-83
4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase	I	Contig12	NmulA1938	COG1947	37	0.003
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig12	NmulA0127	COG1211	40	2e-04
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig12	NmulA0266	COG1211	46	2e-06
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig12	NmulA0312	COG1211	50	3e-07
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig12	NmulA0401	COG1211	45	5e-06
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig12	NmulA0410	COG1211	35	0.004
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig12	NmulA0425	COG1211	46	2e-06
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig12	NmulA0430	COG1211	42	4e-05
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig12	NmulA2127	COG1211	224	3e-60
Deoxyxylulose-5-phosphate synthase	I	Contig12	NmulA0236	COG1154	932	0.0
Deoxyxylulose-5-phosphate synthase	I	Contig12	NmulA0388	COG1154	64	4e-11
Deoxyxylulose-5-phosphate synthase	I	Contig12	NmulA0468	COG1154	74	4e-14

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis	I	Contig12	NmulA2377	COG0821	424	1.0e-120
Esterase/lipase	I	Contig12	NmulA0274	COG0657	35	0.006
Esterase/lipase	I	Contig12	NmulA1827	COG0657	213	2e-56
Esterase/lipase	I	Contig12	NmulA2092	COG0657	47	2e-06
Esterase/lipase	I	Contig12	NmulA2303	COG0657	71	3e-13
Esterase/lipase	I	Contig12	NmulA2412	COG0657	37	0.001

FATTY ACID BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
3-hydroxyacyl-CoA dehydrogenase	I	Contig12	NmulA0097	COG1250	229	7e-61
3-hydroxyacyl-CoA dehydrogenase	I	Contig12	NmulA0171	COG1250	36	0.006
3-hydroxyacyl-CoA dehydrogenase	I	Contig12	NmulA1155	COG1250	36	0.004
3-hydroxyacyl-CoA dehydrogenase	I	Contig12	NmulA1623	COG1250	34	0.010
3-oxoacyl-(acyl-carrier-protein) synthase	I	Contig12	NmulA0098	COG0304	50	2e-07
3-oxoacyl-(acyl-carrier-protein) synthase	I	Contig12	NmulA0398	COG0304	411	1.0e-116
3-oxoacyl-(acyl-carrier-protein) synthase	I	Contig12	NmulA1076	COG0304	491	1.0e-140
3-oxoacyl-(acyl-carrier-protein) synthase	I	Contig12	NmulA1831	COG0304	187	8e-48
Acetyl-CoA acetyltransferase	I	Contig12	NmulA0098	COG0183	310	1e-85
Acetyl-CoA acetyltransferase	I	Contig12	NmulA0398	COG0183	38	0.002
Acetyl-CoA acetyltransferase	I	Contig12	NmulA1072	COG0183	41	9e-05
Acetyl-CoA acetyltransferase	I	Contig12	NmulA1831	COG0183	40	0.001
Acetyl-CoA carboxylase alpha subunit	I	Contig12	NmulA0482	COG0825	41	1e-04
Acetyl-CoA carboxylase alpha subunit	I	Contig12	NmulA1810	COG0825	497	1.0e-142
Acetyl-CoA carboxylase beta subunit	I	Contig12	NmulA1910	COG0777	424	1.0e-120
Acyl carrier protein	I	Contig12	NmulA0229	COG0236	47	3e-07
Acyl carrier protein	I	Contig12	NmulA0275	COG0236	35	0.001
Acyl carrier protein	I	Contig12	NmulA0283	COG0236	50	5e-08
Acyl carrier protein	I	Contig12	NmulA0397	COG0236	51	2e-08
Acyl carrier protein	I	Contig12	NmulA1075	COG0236	66	7e-13
Acyl carrier protein	I	Contig12	NmulA1831	COG0236	41	7e-04
(acyl-carrier-protein) S-malonyltransferase	I	Contig12	NmulA1073	COG0331	331	5e-92
(acyl-carrier-protein) S-malonyltransferase	I	Contig12	NmulA1831	COG0331	176	1e-44
Biotin carboxylase	I	Contig12	NmulA0134	COG0439	59	4e-10
Biotin carboxylase	I	Contig12	NmulA0479	COG0439	88	3e-18
Biotin carboxylase	I	Contig12	NmulA0611	COG0439	52	6e-08
Biotin carboxylase	I	Contig12	NmulA0943	COG0439	507	1.0e-144
Biotin carboxylase	I	Contig12	NmulA1722	COG0439	42	9e-05
Biotin carboxylase	I	Contig12	NmulA2250	COG0439	58	3e-09
Biotin carboxylase	I	Contig12	NmulA2251	COG0439	70	9e-13
Biotin carboxylase	I	Contig12	NmulA2491	COG0439	86	3e-18
Biotin carboxylase	I	Contig12	NmulA2752	COG0439	613	1.0e-177
Biotin carboxyl carrier protein	I	Contig12	NmulA0359	COG0511	51	2e-07
Biotin carboxyl carrier protein	I	Contig12	NmulA0515	COG0511	50	4e-07
Biotin carboxyl carrier protein	I	Contig12	NmulA0856	COG0511	40	3e-04
Biotin carboxyl carrier protein	I	Contig12	NmulA0923	COG0511	35	0.008
Biotin carboxyl carrier protein	I	Contig12	NmulA0943	COG0511	81	4e-16
Biotin carboxyl carrier protein	I	Contig12	NmulA2753	COG0511	117	5e-28
Enoyl-CoA hydratase/carnithine racemase	I	Contig12	NmulA0097	COG1024	92	1e-19

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Fatty acid desaturase	I	Contig12	NmulA0268	COG3239	48	1e-06
Fatty acid desaturase	I	Contig12	NmulA1495	COG3239	76	5e-15
Fatty-acid desaturase	I	Contig12	NmulA2141	COG1398	261	7e-71
Fatty acid/phospholipid biosynthesis enzyme	I	Contig12	NmulA1071	COG0416	432	1.0e-122
Long-chain acyl-CoA synthetase (AMP-forming)	I	Contig12	NmulA0095	COG1022	491	1.0e-140
Long-chain acyl-CoA synthetase (AMP-forming)	I	Contig12	NmulA0231	COG1022	157	3e-39
Long-chain acyl-CoA synthetase (AMP-forming)	I	Contig12	NmulA0968	COG1022	163	2e-41
Long-chain acyl-CoA synthetase (AMP-forming)	I	Contig12	NmulA1417	COG1022	455	1.0e-129
Long-chain acyl-CoA synthetase (AMP-forming)	I	Contig12	NmulA1829	COG1022	125	6e-29
Long-chain acyl-CoA synthetase (AMP-forming)	I	Contig12	NmulA1830	COG1022	129	1e-30
Long-chain acyl-CoA synthetase (AMP-forming)	I	Contig12	NmulA1832	COG1022	153	1e-37
Long-chain acyl-CoA synthetase (AMP-forming)	I	Contig12	NmulA1867	COG1022	88	1e-18
Long-chain acyl-CoA synthetase (AMP-forming)	I	Contig12	NmulA1868	COG1022	60	3e-10
Long-chain acyl-CoA synthetase (AMP-forming)	I	Contig12	NmulA2670	COG1022	219	3e-58
Long-chain fatty acid transport protein	I	Contig12	NmulA0500	COG2067	257	1e-69
Lysophospholipase	I	Contig12	NmulA0273	COG2267	51	1e-07
Lysophospholipase	I	Contig12	NmulA0274	COG2267	53	3e-08
Lysophospholipase	I	Contig12	NmulA1131	COG2267	54	1e-08
Lysophospholipase	I	Contig12	NmulA1163	COG2267	39	3e-04
Lysophospholipase	I	Contig12	NmulA1494	COG2267	55	7e-09
Lysophospholipase	I	Contig12	NmulA1582	COG2267	55	8e-09
Lysophospholipase	I	Contig12	NmulA1834	COG2267	37	0.002
Lysophospholipase	I	Contig12	NmulA2092	COG2267	64	9e-12
Lysophospholipase	I	Contig12	NmulA2273	COG2267	35	0.007
Lysophospholipase	I	Contig12	NmulA2303	COG2267	45	2e-05
Lysophospholipase	I	Contig12	NmulA2412	COG2267	37	0.001

MENAQUINONE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig12	NmulA0095	COG0318	261	9e-71
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig12	NmulA0231	COG0318	266	3e-72
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig12	NmulA0291	COG0318	48	2e-06
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig12	NmulA0968	COG0318	294	9e-81
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig12	NmulA1417	COG0318	243	2e-65
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig12	NmulA1829	COG0318	278	6e-75
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig12	NmulA1830	COG0318	279	8e-76
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig12	NmulA1832	COG0318	325	1e-89
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig12	NmulA1867	COG0318	123	2e-29
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig12	NmulA1868	COG0318	169	2e-43
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig12	NmulA2647	COG0318	40	5e-04
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig12	NmulA2670	COG0318	355	4e-99

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Methylmalonyl-CoA mutase C-terminal domain/subunit (cobalamin-binding)	I	Contig12	NmulA0045	COG2185	51	4e-07
Mevalonate kinase	I	Contig12	NmulA1938	COG1577	108	6e-25
Mevalonate pyrophosphate decarboxylase	I	Contig12	NmulA1938	COG3407	36	0.004
Oligoketide cyclase/lipid transport protein	I	Contig12	NmulA0350	COG2867	36	0.002
Oligoketide cyclase/lipid transport protein	I	Contig12	NmulA1202	COG2867	160	4e-41
Penicillin tolerance protein	I	Contig12	NmulA0089	COG0761	407	1.0e-115
Phosphatidylglycerophosphatase A and related protein	I	Contig12	NmulA0014	COG1267	112	2e-26
Phosphatidylglycerophosphate synthase	I	Contig12	NmulA0404	COG0558	60	3e-10
Phosphatidylglycerophosphate synthase	I	Contig12	NmulA0470	COG0558	39	3e-04
Phosphatidylglycerophosphate synthase	I	Contig12	NmulA1272	COG0558	107	6e-25
Phosphatidylserine decarboxylase	I	Contig12	NmulA0681	COG0688	189	2e-49
Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase	I	Contig12	NmulA0413	COG1502	63	3e-11
Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase	I	Contig12	NmulA1523	COG1502	126	5e-30
Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase	I	Contig12	NmulA1712	COG1502	198	8e-52
Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase	I	Contig12	NmulA2621	COG1502	80	1e-16
Phosphatidylserine synthase	I	Contig12	NmulA0404	COG1183	41	1e-04
Phosphatidylserine synthase	I	Contig12	NmulA0470	COG1183	191	5e-50
Phospholipase/lecithinase/hemolysin	I	Contig12	NmulA1186	COG3240	147	9e-37
Phosphopantetheinyl transferase (holo-ACP synthase)	I	Contig12	NmulA1760	COG0736	145	1e-36
Phosphopantetheinyl transferase (holo-ACP synthase)	I	Contig12	NmulA1833	COG0736	41	1e-04
Phytoene/squalene synthetase	I	Contig12	NmulA0957	COG1562	97	2e-21
Phytoene/squalene synthetase	I	Contig12	NmulA2343	COG1562	246	2e-66
Poly(3-hydroxyalkanoate) synthetase	I	Contig12	NmulA2092	COG3243	37	0.002
sn-1 2-diacylglycerol ethanolamine- and cholinephosphotranferase	I	Contig12	NmulA0404	COG5050	39	7e-04
Sphingosine kinase	I	Contig12	NmulA0405	COG1597	72	4e-14
Squalene cyclase	I	Contig12	NmulA2556	COG1657	235	7e-63
Undecaprenyl pyrophosphate synthase	I	Contig12	NmulA0661	COG0020	308	2e-85

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