Coenzyme Metabolism

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase	H	Contig54	Nmar0555	COG0043	563	1.0e-162
3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase	H	Contig54	Nmar1597	COG0043	359	1.0e-100
5 10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	H	Contig54	Nmar1117	COG0190	345	3e-96
5-formyltetrahydrofolate cyclo-ligase	H	Contig54	Nmar1118	COG0212	146	9e-37
6-pyruvoyl-tetrahydropterin synthase	H	Contig54	Nmar1469	COG0720	57	1e-09
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig54	Nmar0090	COG1120	138	5e-34
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig54	Nmar0295	COG1120	109	4e-25
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig54	Nmar0329	COG1120	207	6e-55
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig54	Nmar0475	COG1120	156	3e-39
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig54	Nmar0483	COG1120	157	7e-40
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig54	Nmar0516	COG1120	109	3e-25
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig54	Nmar0652	COG1120	143	2e-35
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig54	Nmar0874	COG1120	164	4e-42
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig54	Nmar1064	COG1120	125	3e-30
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig54	Nmar1104	COG1120	56	1e-08
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig54	Nmar1245	COG1120	41	3e-04
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig54	Nmar1284	COG1120	145	3e-36
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig54	Nmar1654	COG1120	188	3e-49
ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	H	Contig54	Nmar1713	COG1120	130	7e-32
ABC-type cobalamin transport system ATPase component	H	Contig54	Nmar0090	COG4138	63	2e-11
ABC-type cobalamin transport system ATPase component	H	Contig54	Nmar0295	COG4138	75	1e-14
ABC-type cobalamin transport system ATPase component	H	Contig54	Nmar0329	COG4138	101	7e-23
ABC-type cobalamin transport system ATPase component	H	Contig54	Nmar0475	COG4138	76	3e-15
ABC-type cobalamin transport system ATPase component	H	Contig54	Nmar0483	COG4138	59	3e-10
ABC-type cobalamin transport system ATPase component	H	Contig54	Nmar0516	COG4138	60	2e-10
ABC-type cobalamin transport system ATPase component	H	Contig54	Nmar0652	COG4138	56	3e-09
ABC-type cobalamin transport system ATPase component	H	Contig54	Nmar0874	COG4138	63	2e-11
ABC-type cobalamin transport system ATPase component	H	Contig54	Nmar1064	COG4138	69	5e-13
ABC-type cobalamin transport system ATPase component	H	Contig54	Nmar1104	COG4138	52	2e-07
ABC-type cobalamin transport system ATPase component	H	Contig54	Nmar1284	COG4138	67	1e-12
ABC-type cobalamin transport system ATPase component	H	Contig54	Nmar1654	COG4138	89	4e-19
ABC-type cobalamin transport system ATPase component	H	Contig54	Nmar1713	COG4138	62	4e-11
ABC-type thiamine transport system ATPase component	H	Contig54	Nmar0090	COG3840	97	2e-21
ABC-type thiamine transport system ATPase component	H	Contig54	Nmar0295	COG3840	71	3e-13
ABC-type thiamine transport system ATPase component	H	Contig54	Nmar0329	COG3840	113	2e-26
ABC-type thiamine transport system ATPase component	H	Contig54	Nmar0475	COG3840	102	4e-23
ABC-type thiamine transport system ATPase component	H	Contig54	Nmar0483	COG3840	108	5e-25
ABC-type thiamine transport system ATPase component	H	Contig54	Nmar0516	COG3840	65	5e-12
ABC-type thiamine transport system ATPase component	H	Contig54	Nmar0652	COG3840	111	9e-26
ABC-type thiamine transport system ATPase component	H	Contig54	Nmar0874	COG3840	123	1e-29
ABC-type thiamine transport system ATPase component	H	Contig54	Nmar1064	COG3840	91	1e-19
ABC-type thiamine transport system ATPase component	H	Contig54	Nmar1104	COG3840	48	3e-06
ABC-type thiamine transport system ATPase component	H	Contig54	Nmar1284	COG3840	148	5e-37
ABC-type thiamine transport system ATPase component	H	Contig54	Nmar1654	COG3840	100	8e-23
ABC-type thiamine transport system ATPase component	H	Contig54	Nmar1713	COG3840	118	2e-28
ABC-type tungstate transport system periplasmic component	H	Contig54	Nmar0481	COG4662	50	2e-07

BIOTIN BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
7-keto-8-aminopelargonate synthetase	H	Contig54	Nmar0132	COG0156	40	3e-04
7-keto-8-aminopelargonate synthetase	H	Contig54	Nmar0341	COG0156	38	0.001
7-keto-8-aminopelargonate synthetase	H	Contig54	Nmar0819	COG0156	344	7e-96
7-keto-8-aminopelargonate synthetase	H	Contig54	Nmar1291	COG0156	37	0.003
7-keto-8-aminopelargonate synthetase	H	Contig54	Nmar1345	COG0156	41	2e-04
7-keto-8-aminopelargonate synthetase	H	Contig54	Nmar1557	COG0156	41	9e-05
7-keto-8-aminopelargonate synthetase	H	Contig54	Nmar1748	COG0156	43	4e-05
7-keto-8-aminopelargonate synthetase	H	Contig54	Nmar1793	COG0156	41	2e-04
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	H	Contig54	Nmar0148	COG0161	119	4e-28
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	H	Contig54	Nmar0490	COG0161	181	1e-46
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	H	Contig54	Nmar0822	COG0161	424	1.0e-120
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	H	Contig54	Nmar1017	COG0161	134	1e-32
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	H	Contig54	Nmar1291	COG0161	314	7e-87
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	H	Contig54	Nmar1345	COG0161	209	3e-55
Biotin-(acetyl-CoA carboxylase) ligase	H	Contig54	Nmar0984	COG0340	183	1e-47
Biotin synthase	H	Contig54	Nmar0201	COG0502	49	5e-07
Biotin synthase	H	Contig54	Nmar0554	COG0502	57	2e-09
Biotin synthase	H	Contig54	Nmar0579	COG0502	36	0.009
Biotin synthase	H	Contig54	Nmar0592	COG0502	102	6e-23
Biotin synthase	H	Contig54	Nmar0593	COG0502	95	1e-20
Biotin synthase	H	Contig54	Nmar0742	COG0502	61	1e-10
Biotin synthase	H	Contig54	Nmar0821	COG0502	306	2e-84
Biotin synthase	H	Contig54	Nmar1261	COG0502	48	1e-06
Dethiobiotin synthetase	H	Contig54	Nmar0079	COG0132	48	1e-06
Dethiobiotin synthetase	H	Contig54	Nmar0823	COG0132	170	6e-44
Dethiobiotin synthetase	H	Contig54	Nmar1584	COG0132	46	3e-06

COBALAMIN BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
ATP:corrinoid adenosyltransferase	H	Contig54	Nmar0078	COG2109	198	2e-52
Cobalamin-5-phosphate synthase	H	Contig54	Nmar0332	COG0368	37	0.003
Cobalamin-5-phosphate synthase	H	Contig54	Nmar1582	COG0368	130	9e-32
Cobalamin biosynthesis protein CbiD	H	Contig54	Nmar0083	COG1903	314	7e-87
Cobalamin biosynthesis protein CbiG	H	Contig54	Nmar0082	COG2073	117	1e-27
Cobalamin biosynthesis protein CobD/CbiB	H	Contig54	Nmar1583	COG1270	269	1e-73
Cobyric acid synthase	H	Contig54	Nmar0079	COG1492	59	6e-10
Cobyric acid synthase	H	Contig54	Nmar0779	COG1492	39	2e-04
Cobyric acid synthase	H	Contig54	Nmar0823	COG1492	71	1e-13
Cobyric acid synthase	H	Contig54	Nmar1478	COG1492	41	6e-05
Cobyric acid synthase	H	Contig54	Nmar1584	COG1492	282	2e-77
Cobyrinic acid a c-diamide synthase	H	Contig54	Nmar0079	COG1797	499	1.0e-142
Cobyrinic acid a c-diamide synthase	H	Contig54	Nmar0779	COG1797	47	1e-06
Cobyrinic acid a c-diamide synthase	H	Contig54	Nmar0823	COG1797	51	5e-08
Cobyrinic acid a c-diamide synthase	H	Contig54	Nmar1478	COG1797	34	0.007
Cobyrinic acid a c-diamide synthase	H	Contig54	Nmar1584	COG1797	51	9e-08
NaMN:DMB phosphoribosyltransferase	H	Contig54	Nmar0322	COG2038	201	6e-53
Precorrin-2 methylase	H	Contig54	Nmar0005	COG2243	70	2e-13
Precorrin-2 methylase	H	Contig54	Nmar0058	COG2243	179	1e-46
Precorrin-2 methylase	H	Contig54	Nmar0059	COG2243	75	7e-15
Precorrin-2 methylase	H	Contig54	Nmar0492	COG2243	81	7e-17
Precorrin-2 methylase	H	Contig54	Nmar1752	COG2243	73	1e-14
Precorrin-3B methylase	H	Contig54	Nmar0005	COG1010	73	1e-14
Precorrin-3B methylase	H	Contig54	Nmar0058	COG1010	62	4e-11
Precorrin-3B methylase	H	Contig54	Nmar0059	COG1010	73	3e-14
Precorrin-3B methylase	H	Contig54	Nmar0492	COG1010	80	2e-16
Precorrin-3B methylase	H	Contig54	Nmar1752	COG1010	316	8e-88
Precorrin-6B methylase 1	H	Contig54	Nmar0005	COG2241	144	5e-36
Precorrin-6B methylase 1	H	Contig54	Nmar0058	COG2241	81	6e-17
Precorrin-6B methylase 1	H	Contig54	Nmar0059	COG2241	56	3e-09
Precorrin-6B methylase 1	H	Contig54	Nmar0492	COG2241	56	3e-09
Precorrin-6B methylase 1	H	Contig54	Nmar1297	COG2241	60	2e-10
Precorrin-6B methylase 1	H	Contig54	Nmar1752	COG2241	77	2e-15
Precorrin-6B methylase 2	H	Contig54	Nmar0057	COG2242	189	1e-49
Precorrin-6B methylase 2	H	Contig54	Nmar0190	COG2242	38	4e-04
Precorrin-6B methylase 2	H	Contig54	Nmar0629	COG2242	39	3e-04
Precorrin-6B methylase 2	H	Contig54	Nmar0690	COG2242	55	5e-09
Precorrin-6B methylase 2	H	Contig54	Nmar0755	COG2242	36	0.002
Precorrin-6B methylase 2	H	Contig54	Nmar1381	COG2242	36	0.002
Precorrin-6B methylase 2	H	Contig54	Nmar1457	COG2242	54	2e-08
Precorrin-6B methylase 2	H	Contig54	Nmar1775	COG2242	41	9e-05
Precorrin isomerase	H	Contig54	Nmar0080	COG2082	186	1e-48

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5 6-dimethylbenzimidazole phosphoribosyltransferase)	H	Contig54	Nmar0351	COG4547	36	0.006

COBALAMIN BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Uroporphyrinogen-III methylase	H	Contig54	Nmar0005	COG0007	45	4e-06
Uroporphyrinogen-III methylase	H	Contig54	Nmar0058	COG0007	76	2e-15
Uroporphyrinogen-III methylase	H	Contig54	Nmar0059	COG0007	182	2e-47
Uroporphyrinogen-III methylase	H	Contig54	Nmar0492	COG0007	298	2e-82
Uroporphyrinogen-III methylase	H	Contig54	Nmar1752	COG0007	102	3e-23

COENZYME A BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Dephospho-CoA kinase	H	Contig54	Nmar1780	COG0237	75	3e-15
Ketol-acid reductoisomerase	H	Contig54	Nmar0635	COG0059	47	2e-06
Ketol-acid reductoisomerase	H	Contig54	Nmar0959	COG0059	436	1.0e-124
Ketol-acid reductoisomerase	H	Contig54	Nmar0964	COG0059	42	8e-05
Ketopantoate hydroxymethyltransferase	H	Contig54	Nmar1720	COG0413	345	2e-96
Ketopantoate reductase	H	Contig54	Nmar0170	COG1893	35	0.007
Ketopantoate reductase	H	Contig54	Nmar0180	COG1893	40	2e-04
Ketopantoate reductase	H	Contig54	Nmar0635	COG1893	41	1e-04
Phosphopantetheine adenylyltransferase	H	Contig54	Nmar0960	COG0669	46	1e-06
Phosphopantetheine adenylyltransferase	H	Contig54	Nmar1298	COG0669	36	0.002
Phosphopantetheine adenylyltransferase	H	Contig54	Nmar1494	COG0669	35	0.003
Phosphopantetheine adenylyltransferase	H	Contig54	Nmar1732	COG0669	43	1e-05
Phosphopantothenoylcysteine synthetase/decarboxylase	H	Contig54	Nmar0771	COG0452	42	2e-05
Phosphopantothenoylcysteine synthetase/decarboxylase	H	Contig54	Nmar1721	COG0452	277	9e-76

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Coenzyme F390 synthetase	H	Contig54	Nmar0701	COG1541	45	2e-05
Coenzyme F390 synthetase	H	Contig54	Nmar0866	COG1541	41	3e-04

DEOXYXYLULOSE PATHWAY OF TERPENOID BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Deoxyxylulose-5-phosphate synthase	H	Contig54	Nmar0299	COG1154	71	3e-13
Deoxyxylulose-5-phosphate synthase	H	Contig54	Nmar0300	COG1154	217	8e-58

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Dihydrofolate reductase	H	Contig54	Nmar1612	COG0262	38	8e-04
Dihydropteroate synthase	H	Contig54	Nmar1570	COG0294	163	1e-41
Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 1	H	Contig54	Nmar1548	COG1179	113	3e-26

FAD BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
3 4-dihydroxy-2-butanone 4-phosphate synthase	H	Contig54	Nmar1616	COG0108	207	5e-55
3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase	H	Contig54	Nmar0049	COG0175	205	2e-54
3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase	H	Contig54	Nmar0105	COG0175	52	8e-08
FAD synthase	H	Contig54	Nmar0423	COG0196	37	0.001
FAD synthase	H	Contig54	Nmar1494	COG0196	35	0.003
Pyrimidine deaminase	H	Contig54	Nmar0947	COG0117	39	2e-04
Pyrimidine reductase riboflavin biosynthesis	H	Contig54	Nmar1612	COG1985	179	1e-46
Riboflavin synthase alpha chain	H	Contig54	Nmar1617	COG0307	211	2e-56
Riboflavin synthase beta-chain	H	Contig54	Nmar1615	COG0054	113	5e-27
riboflavin synthase	H	Contig54	Nmar1615	COG1731	33	0.009

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Flavoprotein involved in thiazole biosynthesis	H	Contig54	Nmar0631	COG1635	51	1e-07
Flavoprotein involved in thiazole biosynthesis	H	Contig54	Nmar0672	COG1635	43	5e-05
Flavoprotein involved in thiazole biosynthesis	H	Contig54	Nmar0678	COG1635	289	1e-79
Flavoprotein involved in thiazole biosynthesis	H	Contig54	Nmar1220	COG1635	38	0.002
Geranylgeranyl pyrophosphate synthase	H	Contig54	Nmar0269	COG0142	38	0.001
Geranylgeranyl pyrophosphate synthase	H	Contig54	Nmar0287	COG0142	172	3e-44
Geranylgeranyl pyrophosphate synthase	H	Contig54	Nmar0312	COG0142	258	4e-70
Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)	H	Contig54	Nmar0273	COG0189	59	8e-10
Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)	H	Contig54	Nmar0846	COG0189	48	1e-06
Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)	H	Contig54	Nmar1008	COG0189	48	2e-06
Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)	H	Contig54	Nmar1085	COG0189	37	0.008
Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)	H	Contig54	Nmar1119	COG0189	49	5e-07
Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)	H	Contig54	Nmar1288	COG0189	166	1e-42
Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)	H	Contig54	Nmar1295	COG0189	179	2e-46
GTP:adenosylcobinamide-phosphate guanylyltransferase	H	Contig54	Nmar0157	COG2266	36	0.003
GTP:adenosylcobinamide-phosphate guanylyltransferase	H	Contig54	Nmar0424	COG2266	39	3e-04
GTP:adenosylcobinamide-phosphate guanylyltransferase	H	Contig54	Nmar0541	COG2266	38	8e-04
GTP:adenosylcobinamide-phosphate guanylyltransferase	H	Contig54	Nmar0843	COG2266	44	1e-05
GTP:adenosylcobinamide-phosphate guanylyltransferase	H	Contig54	Nmar1581	COG2266	114	5e-27
GTP cyclohydrolase I	H	Contig54	Nmar0038	COG0302	216	7e-58

HEME BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Coproporphyrinogen III oxidase and related Fe-S oxidoreductase	H	Contig54	Nmar0201	COG0635	61	1e-10
Coproporphyrinogen III oxidase and related Fe-S oxidoreductase	H	Contig54	Nmar0554	COG0635	36	0.003
Coproporphyrinogen III oxidase and related Fe-S oxidoreductase	H	Contig54	Nmar0579	COG0635	88	2e-18
Coproporphyrinogen III oxidase and related Fe-S oxidoreductase	H	Contig54	Nmar0821	COG0635	35	0.006
Coproporphyrinogen III oxidase and related Fe-S oxidoreductase	H	Contig54	Nmar1261	COG0635	60	4e-10
Delta-aminolevulinic acid dehydratase	H	Contig54	Nmar0509	COG0113	451	1.0e-128
Glutamate-1-semialdehyde aminotransferase	H	Contig54	Nmar0148	COG0001	315	3e-87
Glutamate-1-semialdehyde aminotransferase	H	Contig54	Nmar0490	COG0001	532	1.0e-152
Glutamate-1-semialdehyde aminotransferase	H	Contig54	Nmar0822	COG0001	119	5e-28
Glutamate-1-semialdehyde aminotransferase	H	Contig54	Nmar1017	COG0001	359	1.0e-100
Glutamate-1-semialdehyde aminotransferase	H	Contig54	Nmar1291	COG0001	228	6e-61
Glutamate-1-semialdehyde aminotransferase	H	Contig54	Nmar1345	COG0001	148	7e-37
Glutamate-1-semialdehyde aminotransferase	H	Contig54	Nmar1557	COG0001	37	0.002
Glutamyl-tRNA reductase	H	Contig54	Nmar0265	COG0373	172	4e-44
Glutamyl-tRNA reductase	H	Contig54	Nmar0510	COG0373	309	3e-85
Glutamyl-tRNA reductase	H	Contig54	Nmar0550	COG0373	56	3e-09
Glutamyl-tRNA reductase	H	Contig54	Nmar0635	COG0373	35	0.006
Porphobilinogen deaminase	H	Contig54	Nmar0491	COG0181	341	3e-95
Protoporphyrinogen oxidase	H	Contig54	Nmar0678	COG1232	36	0.003
Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	H	Contig54	Nmar0511	COG1648	126	9e-31
Uroporphyrinogen-III synthase	H	Contig54	Nmar0493	COG1587	135	2e-33

LEUCINE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	H	Contig54	Nmar0192	COG0115	244	6e-66
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	H	Contig54	Nmar0248	COG0115	240	9e-65
Thiamine pyrophosphate-requiring protein	H	Contig54	Nmar0158	COG0028	66	1e-12
Thiamine pyrophosphate-requiring protein	H	Contig54	Nmar0414	COG0028	55	6e-09
Thiamine pyrophosphate-requiring protein	H	Contig54	Nmar1072	COG0028	607	1.0e-175
Thiamine pyrophosphate-requiring protein	H	Contig54	Nmar1719	COG0028	35	0.004

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Lipoate synthase	H	Contig54	Nmar0593	COG0320	37	0.002
Lipoate synthase	H	Contig54	Nmar0821	COG0320	54	2e-08

MENAQUINONE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
1 4-dihydroxy-2-naphthoate octaprenyltransferase	H	Contig54	Nmar0938	COG1575	126	3e-30
2-succinyl-6-hydroxy-2 4-cyclohexadiene-1-carboxylate synthase	H	Contig54	Nmar1072	COG1165	95	9e-21
Dihydroxynaphthoic acid synthase	H	Contig54	Nmar1308	COG0447	148	3e-37
Isochorismate synthase	H	Contig54	Nmar0911	COG1169	204	2e-53
shikimate kinase	H	Contig54	Nmar0041	COG1685	76	4e-15
shikimate kinase	H	Contig54	Nmar0315	COG1685	53	4e-08
shikimate kinase	H	Contig54	Nmar0549	COG1685	189	2e-49
shikimate kinase	H	Contig54	Nmar1718	COG1685	46	4e-06

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Mg-chelatase subunit ChlD	H	Contig54	Nmar1516	COG1240	38	0.002
Mg-chelatase subunit ChlD	H	Contig54	Nmar1641	COG1240	45	1e-05
Mg-chelatase subunit ChlI	H	Contig54	Nmar0242	COG1239	40	4e-04
Mg-chelatase subunit ChlI	H	Contig54	Nmar1515	COG1239	62	3e-11
Mg-chelatase subunit ChlI	H	Contig54	Nmar1643	COG1239	75	1e-14
Molybdenum cofactor biosynthesis protein	H	Contig54	Nmar0037	COG2896	37	0.001
Molybdenum cofactor biosynthesis protein	H	Contig54	Nmar0115	COG2896	74	2e-14
Molybdenum cofactor biosynthesis protein	H	Contig54	Nmar0592	COG2896	42	9e-05
Molybdenum cofactor biosynthesis protein	H	Contig54	Nmar0742	COG2896	40	2e-04
Molybdenum cofactor biosynthesis protein	H	Contig54	Nmar0821	COG2896	44	1e-05
Molybdenum cofactor biosynthesis protein	H	Contig54	Nmar1385	COG2896	43	5e-05
Molybdenum cofactor biosynthesis protein	H	Contig54	Nmar1529	COG2896	44	2e-05
Molybdopterin converting factor small subunit	H	Contig54	Nmar1429	COG1977	43	2e-05
Molybdopterin converting factor small subunit	H	Contig54	Nmar1548	COG1977	46	5e-06
Molybdopterin-guanine dinucleotide biosynthesis protein A	H	Contig54	Nmar0135	COG0746	38	5e-04
Molybdopterin-guanine dinucleotide biosynthesis protein A	H	Contig54	Nmar0157	COG0746	48	6e-07
Molybdopterin-guanine dinucleotide biosynthesis protein A	H	Contig54	Nmar0424	COG0746	47	2e-06
Molybdopterin-guanine dinucleotide biosynthesis protein A	H	Contig54	Nmar0541	COG0746	43	2e-05
Molybdopterin-guanine dinucleotide biosynthesis protein A	H	Contig54	Nmar0662	COG0746	40	1e-04
Molybdopterin-guanine dinucleotide biosynthesis protein A	H	Contig54	Nmar0843	COG0746	51	4e-08
Molybdopterin-guanine dinucleotide biosynthesis protein A	H	Contig54	Nmar1581	COG0746	65	4e-12
Molybdopterin-guanine dinucleotide biosynthesis protein	H	Contig54	Nmar0531	COG1763	41	2e-04

NAD BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Aspartate oxidase	H	Contig54	Nmar0258	COG0029	369	1.0e-103
NAD synthase	H	Contig54	Nmar0040	COG0171	36	0.003
NAD synthase	H	Contig54	Nmar0340	COG0171	45	7e-06
NAD synthase	H	Contig54	Nmar0966	COG0171	212	2e-56
NAD synthase	H	Contig54	Nmar1573	COG0171	48	2e-06
Nicotinamide mononucleotide adenylyltransferase	H	Contig54	Nmar0960	COG1056	147	4e-37
Nicotinamide mononucleotide adenylyltransferase	H	Contig54	Nmar1494	COG1056	34	0.006
Nicotinamide mononucleotide adenylyltransferase	H	Contig54	Nmar1732	COG1056	118	3e-28
Nicotinate-nucleotide pyrophosphorylase	H	Contig54	Nmar1237	COG0157	278	2e-76
Nicotinic acid mononucleotide adenylyltransferase	H	Contig54	Nmar0960	COG1057	35	0.003
Nicotinic acid mononucleotide adenylyltransferase	H	Contig54	Nmar1298	COG1057	36	0.002
Nicotinic acid mononucleotide adenylyltransferase	H	Contig54	Nmar1494	COG1057	34	0.006
Nicotinic acid mononucleotide adenylyltransferase	H	Contig54	Nmar1732	COG1057	42	3e-05
Quinolinate synthase	H	Contig54	Nmar1239	COG0379	385	1.0e-108

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Precorrin-4 methylase	H	Contig54	Nmar0005	COG2875	47	2e-06
Precorrin-4 methylase	H	Contig54	Nmar0058	COG2875	79	2e-16
Precorrin-4 methylase	H	Contig54	Nmar0059	COG2875	327	4e-91
Precorrin-4 methylase	H	Contig54	Nmar0131	COG2875	36	0.005
Precorrin-4 methylase	H	Contig54	Nmar0492	COG2875	163	1e-41
Precorrin-4 methylase	H	Contig54	Nmar1752	COG2875	79	4e-16
Predicted glutamine amidotransferase involved in pyridoxine biosynthesis	H	Contig54	Nmar0079	COG0311	46	4e-06
Predicted glutamine amidotransferase involved in pyridoxine biosynthesis	H	Contig54	Nmar0779	COG0311	34	0.007
Predicted glutamine amidotransferase involved in pyridoxine biosynthesis	H	Contig54	Nmar1478	COG0311	214	3e-57
Predicted HD superfamily hydrolase involved in NAD metabolism	H	Contig54	Nmar1706	COG1713	39	5e-04
Pterin-4a-carbinolamine dehydratase	H	Contig54	Nmar1468	COG2154	108	6e-26

PYRIDOXAL PHOSPHATE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Lactate dehydrogenase and related dehydrogenase	H	Contig54	Nmar0412	COG1052	334	4e-93
Lactate dehydrogenase and related dehydrogenase	H	Contig54	Nmar0635	COG1052	40	2e-04
Lactate dehydrogenase and related dehydrogenase	H	Contig54	Nmar0964	COG1052	51	1e-07
Lactate dehydrogenase and related dehydrogenase	H	Contig54	Nmar1258	COG1052	245	4e-66
Phosphoserine aminotransferase	H	Contig54	Nmar0341	COG1932	41	1e-04
Phosphoserine aminotransferase	H	Contig54	Nmar1731	COG1932	78	1e-15
Pyridoxal phosphate biosynthesis protein	H	Contig54	Nmar1069	COG1995	42	8e-05
Pyridoxal/pyridoxine/pyridoxamine kinase	H	Contig54	Nmar0542	COG2240	82	6e-17
Pyridoxal/pyridoxine/pyridoxamine kinase	H	Contig54	Nmar1745	COG2240	38	0.001
Pyridoxine biosynthesis enzyme	H	Contig54	Nmar0914	COG0214	37	0.002
Pyridoxine biosynthesis enzyme	H	Contig54	Nmar0916	COG0214	35	0.005
Pyridoxine biosynthesis enzyme	H	Contig54	Nmar1479	COG0214	394	1.0e-111
Pyridoxine biosynthesis enzyme	H	Contig54	Nmar1525	COG0214	37	0.002

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C	H	Contig54	Nmar0288	COG5424	124	7e-30
Pyruvate decarboxylase	H	Contig54	Nmar1072	COG3961	178	6e-46
S-adenosylhomocysteine hydrolase	H	Contig54	Nmar0964	COG0499	513	1.0e-146
S-adenosylmethionine synthetase	H	Contig54	Nmar0085	COG0192	627	0.0
Tetrahydromethanopterin S-methyltransferase subunit A	H	Contig54	Nmar1747	COG4063	105	2e-24

THIAMINE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2	H	Contig54	Nmar0136	COG0476	36	0.004
Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2	H	Contig54	Nmar1548	COG0476	214	1e-56
Hydroxyethylthiazole kinase sugar kinase family	H	Contig54	Nmar0691	COG2145	49	5e-07
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	H	Contig54	Nmar0542	COG0351	246	3e-66
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	H	Contig54	Nmar0691	COG0351	48	9e-07
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	H	Contig54	Nmar1745	COG0351	41	1e-04
Thiamine biosynthesis ATP pyrophosphatase	H	Contig54	Nmar0048	COG0301	67	2e-12
Thiamine biosynthesis ATP pyrophosphatase	H	Contig54	Nmar0935	COG0301	35	0.009
Thiamine biosynthesis ATP pyrophosphatase	H	Contig54	Nmar1725	COG0301	64	1e-11
Thiamine biosynthesis protein ThiC	H	Contig54	Nmar0543	COG0422	561	1.0e-161
Thiamine biosynthesis protein ThiH	H	Contig54	Nmar0115	COG1060	39	0.001
Thiamine biosynthesis protein ThiH	H	Contig54	Nmar0201	COG1060	44	2e-05
Thiamine biosynthesis protein ThiH	H	Contig54	Nmar0554	COG1060	379	1.0e-106
Thiamine biosynthesis protein ThiH	H	Contig54	Nmar0592	COG1060	372	1.0e-104
Thiamine biosynthesis protein ThiH	H	Contig54	Nmar0593	COG1060	224	1e-59
Thiamine biosynthesis protein ThiH	H	Contig54	Nmar0742	COG1060	371	1.0e-104
Thiamine biosynthesis protein ThiH	H	Contig54	Nmar0821	COG1060	73	3e-14
Thiamine monophosphate kinase	H	Contig54	Nmar0582	COG0611	81	1e-16
Thiamine monophosphate kinase	H	Contig54	Nmar0780	COG0611	50	9e-07
Thiamine monophosphate kinase	H	Contig54	Nmar1448	COG0611	198	3e-52
Thiamine monophosphate synthase	H	Contig54	Nmar0914	COG0352	42	4e-05
Thiamine monophosphate synthase	H	Contig54	Nmar0916	COG0352	45	8e-06
Thiamine monophosphate synthase	H	Contig54	Nmar1479	COG0352	36	0.004

TRANSCRIPTIONAL REGULATORS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Transcriptional regulator of a riboflavin/FAD biosynthetic operon	H	Contig54	Nmar1301	COG1339	167	8e-43

TRYPTOPHAN BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Anthranilate/para-aminobenzoate synthase component I	H	Contig54	Nmar0911	COG0147	447	1.0e-127
Anthranilate/para-aminobenzoate synthase component II	H	Contig54	Nmar0068	COG0512	64	5e-12
Anthranilate/para-aminobenzoate synthase component II	H	Contig54	Nmar0661	COG0512	66	2e-12
Anthranilate/para-aminobenzoate synthase component II	H	Contig54	Nmar0912	COG0512	277	3e-76
Anthranilate/para-aminobenzoate synthase component II	H	Contig54	Nmar0919	COG0512	44	3e-05
Anthranilate/para-aminobenzoate synthase component II	H	Contig54	Nmar1086	COG0512	81	1e-16
Anthranilate/para-aminobenzoate synthase component II	H	Contig54	Nmar1310	COG0512	59	2e-10
Anthranilate/para-aminobenzoate synthase component II	H	Contig54	Nmar1554	COG0512	50	1e-07
Anthranilate/para-aminobenzoate synthase component II	H	Contig54	Nmar1573	COG0512	96	5e-21

UBIQUINONE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig54	Nmar0106	COG2227	58	1e-09
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig54	Nmar0190	COG2227	34	0.006
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig54	Nmar0610	COG2227	39	0.002
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig54	Nmar0629	COG2227	58	3e-10
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig54	Nmar0690	COG2227	36	0.004
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig54	Nmar1315	COG2227	36	0.002
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig54	Nmar1366	COG2227	46	2e-06
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig54	Nmar1457	COG2227	71	1e-13
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig54	Nmar1722	COG2227	55	9e-09
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase	H	Contig54	Nmar1775	COG2227	41	8e-05
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig54	Nmar0258	COG0654	36	0.007
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig54	Nmar0631	COG0654	86	6e-18
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig54	Nmar0672	COG0654	39	4e-04
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig54	Nmar0678	COG0654	45	8e-06
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig54	Nmar1220	COG0654	59	8e-10
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase	H	Contig54	Nmar1514	COG0654	67	2e-12
2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase	H	Contig54	Nmar0253	COG0543	98	6e-22
2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase	H	Contig54	Nmar0267	COG0543	92	5e-20
2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase	H	Contig54	Nmar1389	COG0543	163	1e-41
3-polyprenyl-4-hydroxybenzoate decarboxylase	H	Contig54	Nmar0771	COG0163	259	1e-70
3-polyprenyl-4-hydroxybenzoate decarboxylase	H	Contig54	Nmar1721	COG0163	37	0.002
4-hydroxybenzoate polyprenyltransferase and related prenyltransferase	H	Contig54	Nmar0938	COG0382	45	6e-06
4-hydroxybenzoate polyprenyltransferase and related prenyltransferase	H	Contig54	Nmar1225	COG0382	68	5e-13
4-hydroxybenzoate polyprenyltransferase and related prenyltransferase	H	Contig54	Nmar1588	COG0382	67	2e-12
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig54	Nmar0057	COG2226	53	2e-08
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig54	Nmar0190	COG2226	58	4e-10
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig54	Nmar0565	COG2226	46	2e-06
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig54	Nmar0610	COG2226	41	4e-04
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig54	Nmar0629	COG2226	62	3e-11
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig54	Nmar0690	COG2226	43	2e-05
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig54	Nmar0997	COG2226	46	2e-06
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig54	Nmar1315	COG2226	116	2e-27
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig54	Nmar1457	COG2226	80	2e-16
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig54	Nmar1722	COG2226	95	8e-21
Methylase involved in ubiquinone/menaquinone biosynthesis	H	Contig54	Nmar1775	COG2226	45	8e-06

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Uncharacterized protein of heme biosynthesis	H	Contig54	Nmar0069	COG3071	35	0.006
Uncharacterized protein of heme biosynthesis	H	Contig54	Nmar1238	COG3071	41	4e-05

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