Nucleotide Transport and Metabolism

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Adenine deaminase	F	Contig54	Nmar0214	COG1001	36	0.004
Adenine deaminase	F	Contig54	Nmar1578	COG1001	457	1.0e-129
Adenine deaminase	F	Contig54	Nmar1613	COG1001	37	0.002
adenylate kinase	F	Contig54	Nmar0403	COG2019	166	9e-43
adenylate kinase	F	Contig54	Nmar0405	COG2019	35	0.004
adenylate kinase	F	Contig54	Nmar1535	COG2019	36	0.002
adenylate kinase	F	Contig54	Nmar1780	COG2019	39	2e-04
ADP-ribose pyrophosphatase	F	Contig54	Nmar1265	COG1051	39	2e-04
ADP-ribose pyrophosphatase	F	Contig54	Nmar1417	COG1051	43	5e-06
ADP-ribose pyrophosphatase	F	Contig54	Nmar1716	COG1051	47	8e-07
Aspartate carbamoyltransferase regulatory subunit	F	Contig54	Nmar1687	COG1781	165	1e-42
ATP adenylyltransferase (5' 5'''-P-1 P-4-tetraphosphate phosphorylase II)	F	Contig54	Nmar0883	COG4360	37	5e-04
Cytosine/adenosine deaminase	F	Contig54	Nmar0947	COG0590	42	3e-05
Cytosine/adenosine deaminase	F	Contig54	Nmar1471	COG0590	35	0.002
Deoxycytidylate deaminase	F	Contig54	Nmar0947	COG2131	143	6e-36
dGTP triphosphohydrolase	F	Contig54	Nmar1210	COG0232	46	7e-06
dGTP triphosphohydrolase	F	Contig54	Nmar1706	COG0232	55	7e-09
Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase	F	Contig54	Nmar0538	COG0537	41	1e-04
Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase	F	Contig54	Nmar0883	COG0537	130	2e-32
Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase	F	Contig54	Nmar1025	COG0537	110	3e-26
Guanylate kinase	F	Contig54	Nmar0329	COG0194	35	0.006
Guanylate kinase	F	Contig54	Nmar0405	COG0194	34	0.009
Orotate phosphoribosyltransferase homologs	F	Contig54	Nmar0289	COG0856	45	5e-06
Orotate phosphoribosyltransferase homologs	F	Contig54	Nmar1400	COG0856	39	2e-04
Predicted alternative thymidylate synthase	F	Contig54	Nmar0698	COG1351	102	7e-23
Predicted nucleotide kinase	F	Contig54	Nmar0405	COG1618	34	0.006
Predicted nucleotide kinase	F	Contig54	Nmar0531	COG1618	36	0.004
Predicted nucleotide kinase	F	Contig54	Nmar1535	COG4088	36	0.002
Predicted nucleotide kinase (related to CMP and AMP kinase)	F	Contig54	Nmar0403	COG1936	40	1e-04
Predicted nucleotide kinase (related to CMP and AMP kinase)	F	Contig54	Nmar0405	COG1936	38	4e-04
Predicted nucleotide kinase (related to CMP and AMP kinase)	F	Contig54	Nmar1535	COG1936	103	7e-24
Predicted nucleotide kinase (related to CMP and AMP kinase)	F	Contig54	Nmar1780	COG1936	40	1e-04

PURINE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Adenylosuccinate lyase	F	Contig54	Nmar0263	COG0015	94	2e-20
Adenylosuccinate lyase	F	Contig54	Nmar1260	COG0015	96	5e-21
Adenylosuccinate lyase	F	Contig54	Nmar1455	COG0015	439	1.0e-124
Adenylosuccinate synthase	F	Contig54	Nmar1420	COG0104	354	5e-99
Folate-dependent phosphoribosylglycinamide formyltransferase PurN	F	Contig54	Nmar0223	COG0299	156	2e-39
Folate-dependent phosphoribosylglycinamide formyltransferase PurN	F	Contig54	Nmar1114	COG0299	225	2e-60
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	Contig54	Nmar0273	COG0027	55	9e-09
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	Contig54	Nmar0846	COG0027	165	3e-42
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	Contig54	Nmar1085	COG0027	45	3e-05
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	Contig54	Nmar1119	COG0027	41	2e-04
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	Contig54	Nmar1288	COG0027	42	5e-05
Glutamine phosphoribosylpyrophosphate amidotransferase	F	Contig54	Nmar0323	COG0034	146	6e-36
Glutamine phosphoribosylpyrophosphate amidotransferase	F	Contig54	Nmar0781	COG0034	417	1.0e-118
GMP synthase - Glutamine amidotransferase domain	F	Contig54	Nmar0068	COG0518	101	4e-23
GMP synthase - Glutamine amidotransferase domain	F	Contig54	Nmar0661	COG0518	58	6e-10
GMP synthase - Glutamine amidotransferase domain	F	Contig54	Nmar0912	COG0518	108	3e-25
GMP synthase - Glutamine amidotransferase domain	F	Contig54	Nmar1086	COG0518	67	2e-12
GMP synthase - Glutamine amidotransferase domain	F	Contig54	Nmar1310	COG0518	174	5e-45
GMP synthase - Glutamine amidotransferase domain	F	Contig54	Nmar1478	COG0518	46	2e-06
GMP synthase - Glutamine amidotransferase domain	F	Contig54	Nmar1554	COG0518	47	9e-07
GMP synthase - Glutamine amidotransferase domain	F	Contig54	Nmar1573	COG0518	200	2e-52
GMP synthase PP-ATPase domain/subunit	F	Contig54	Nmar0105	COG0519	39	4e-04
GMP synthase PP-ATPase domain/subunit	F	Contig54	Nmar0340	COG0519	39	4e-04
GMP synthase PP-ATPase domain/subunit	F	Contig54	Nmar0966	COG0519	46	4e-06
GMP synthase PP-ATPase domain/subunit	F	Contig54	Nmar1573	COG0519	451	1.0e-128
IMP dehydrogenase/GMP reductase	F	Contig54	Nmar1569	COG0516	108	8e-25
Phosphoribosylamine-glycine ligase	F	Contig54	Nmar0273	COG0151	52	1e-07
Phosphoribosylamine-glycine ligase	F	Contig54	Nmar0846	COG0151	38	0.001
Phosphoribosylamine-glycine ligase	F	Contig54	Nmar1008	COG0151	55	2e-08
Phosphoribosylamine-glycine ligase	F	Contig54	Nmar1085	COG0151	63	1e-10
Phosphoribosylamine-glycine ligase	F	Contig54	Nmar1119	COG0151	542	1.0e-155
Phosphoribosylamine-glycine ligase	F	Contig54	Nmar1288	COG0151	49	3e-07
Phosphoribosylamine-glycine ligase	F	Contig54	Nmar1295	COG0151	44	1e-05
Phosphoribosylaminoimidazole (AIR) synthetase	F	Contig54	Nmar0582	COG0150	327	9e-91
Phosphoribosylaminoimidazole (AIR) synthetase	F	Contig54	Nmar0780	COG0150	45	2e-05
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	Contig54	Nmar0273	COG0026	64	2e-11
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	Contig54	Nmar0846	COG0026	424	1.0e-120
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	Contig54	Nmar1008	COG0026	48	2e-06
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	Contig54	Nmar1085	COG0026	50	8e-07
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	Contig54	Nmar1119	COG0026	50	2e-07
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	Contig54	Nmar1288	COG0026	63	4e-11
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	Contig54	Nmar1295	COG0026	41	1e-04
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	Contig54	Nmar1309	COG0026	41	3e-04
Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase	F	Contig54	Nmar0784	COG0152	184	4e-48
Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	F	Contig54	Nmar0337	COG0041	48	9e-07
Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	F	Contig54	Nmar0847	COG0041	192	2e-50
Phosphoribosylformylglycinamidine (FGAM) synthase glutamine amidotransferase domain	F	Contig54	Nmar0661	COG0047	44	7e-06
Phosphoribosylformylglycinamidine (FGAM) synthase glutamine amidotransferase domain	F	Contig54	Nmar0779	COG0047	284	3e-78
Phosphoribosylformylglycinamidine (FGAM) synthase glutamine amidotransferase domain	F	Contig54	Nmar0919	COG0047	36	0.006
Phosphoribosylformylglycinamidine (FGAM) synthase glutamine amidotransferase domain	F	Contig54	Nmar1478	COG0047	34	0.008
Phosphoribosylformylglycinamidine (FGAM) synthase PurS component	F	Contig54	Nmar0777	COG1828	57	3e-10
Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain	F	Contig54	Nmar0582	COG0046	47	2e-06
Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain	F	Contig54	Nmar0780	COG0046	726	0.0
Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain	F	Contig54	Nmar1448	COG0046	48	8e-07
Phosphoribosylpyrophosphate synthetase	F	Contig54	Nmar0289	COG0462	38	4e-04
Phosphoribosylpyrophosphate synthetase	F	Contig54	Nmar0781	COG0462	43	5e-05
Phosphoribosylpyrophosphate synthetase	F	Contig54	Nmar0988	COG0462	34	0.005
Phosphoribosylpyrophosphate synthetase	F	Contig54	Nmar1400	COG0462	35	0.003
Phosphoribosylpyrophosphate synthetase	F	Contig54	Nmar1774	COG0462	255	2e-69

PURINE SALVAGE

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	Contig54	Nmar0289	COG0503	59	2e-10
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	Contig54	Nmar0781	COG0503	47	3e-06
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	Contig54	Nmar1400	COG0503	159	1e-40
Formyltetrahydrofolate hydrolase	F	Contig54	Nmar0134	COG0788	35	0.003
Formyltetrahydrofolate hydrolase	F	Contig54	Nmar0223	COG0788	250	7e-68
Formyltetrahydrofolate hydrolase	F	Contig54	Nmar1114	COG0788	122	2e-29
Purine nucleoside phosphorylase	F	Contig54	Nmar1401	COG0005	270	7e-74

PYRIMIDINE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Adenylate kinase and related kinase	F	Contig54	Nmar0405	COG0563	38	4e-04
Adenylate kinase and related kinase	F	Contig54	Nmar1535	COG0563	36	0.002
Adenylate kinase and related kinase	F	Contig54	Nmar1707	COG0563	38	4e-04
Aspartate carbamoyltransferase catalytic chain	F	Contig54	Nmar0397	COG0540	173	1e-44
Aspartate carbamoyltransferase catalytic chain	F	Contig54	Nmar1686	COG0540	342	1e-95
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	Contig54	Nmar0206	COG0458	37	0.006
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	Contig54	Nmar0273	COG0458	96	6e-21
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	Contig54	Nmar0846	COG0458	48	1e-06
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	Contig54	Nmar1008	COG0458	71	2e-13
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	Contig54	Nmar1085	COG0458	485	1.0e-138
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	Contig54	Nmar1119	COG0458	36	0.004
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	Contig54	Nmar1123	COG0458	35	0.009
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	Contig54	Nmar1288	COG0458	47	2e-06
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	Contig54	Nmar1295	COG0458	41	1e-04
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	Contig54	Nmar1309	COG0458	39	0.001
Carbamoylphosphate synthase small subunit	F	Contig54	Nmar0068	COG0505	54	7e-09
Carbamoylphosphate synthase small subunit	F	Contig54	Nmar0661	COG0505	57	9e-10
Carbamoylphosphate synthase small subunit	F	Contig54	Nmar0912	COG0505	89	1e-19
Carbamoylphosphate synthase small subunit	F	Contig54	Nmar0919	COG0505	41	2e-04
Carbamoylphosphate synthase small subunit	F	Contig54	Nmar1086	COG0505	432	1.0e-122
Carbamoylphosphate synthase small subunit	F	Contig54	Nmar1310	COG0505	47	1e-06
Carbamoylphosphate synthase small subunit	F	Contig54	Nmar1554	COG0505	37	0.001
Carbamoylphosphate synthase small subunit	F	Contig54	Nmar1573	COG0505	70	4e-13
CTP synthase (UTP-ammonia lyase)	F	Contig54	Nmar0068	COG0504	35	0.003
CTP synthase (UTP-ammonia lyase)	F	Contig54	Nmar0661	COG0504	42	5e-05
CTP synthase (UTP-ammonia lyase)	F	Contig54	Nmar0779	COG0504	43	2e-05
CTP synthase (UTP-ammonia lyase)	F	Contig54	Nmar0912	COG0504	34	0.008
CTP synthase (UTP-ammonia lyase)	F	Contig54	Nmar0919	COG0504	766	0.0
CTP synthase (UTP-ammonia lyase)	F	Contig54	Nmar1086	COG0504	45	9e-06
CTP synthase (UTP-ammonia lyase)	F	Contig54	Nmar1478	COG0504	38	7e-04
CTP synthase (UTP-ammonia lyase)	F	Contig54	Nmar1554	COG0504	43	2e-05
Cytidylate kinase	F	Contig54	Nmar0403	COG1102	34	0.008
Cytidylate kinase	F	Contig54	Nmar0405	COG1102	112	2e-26
Cytidylate kinase	F	Contig54	Nmar0405	COG0283	40	8e-05
Cytidylate kinase	F	Contig54	Nmar1780	COG1102	34	0.007
Dihydroorotase and related cyclic amidohydrolase	F	Contig54	Nmar0214	COG0044	266	4e-72
Dihydroorotase and related cyclic amidohydrolase	F	Contig54	Nmar1578	COG0044	47	4e-06
Dihydroorotase and related cyclic amidohydrolase	F	Contig54	Nmar1613	COG0044	55	1e-08
Dihydroorotate dehydrogenase	F	Contig54	Nmar0916	COG0167	44	1e-05
Dihydroorotate dehydrogenase	F	Contig54	Nmar1390	COG0167	271	5e-74
Dihydroorotate dehydrogenase	F	Contig54	Nmar1525	COG0167	60	3e-10
Dihydroorotate dehydrogenase	F	Contig54	Nmar1569	COG0167	36	0.005
Dihydroorotate dehydrogenase	F	Contig54	Nmar1795	COG0167	34	0.010
Orotate phosphoribosyltransferase	F	Contig54	Nmar0289	COG0461	155	2e-39
Orotate phosphoribosyltransferase	F	Contig54	Nmar1400	COG0461	52	2e-08
Orotidine-5'-phosphate decarboxylase	F	Contig54	Nmar1268	COG0284	35	0.007
Orotidine-5'-phosphate decarboxylase	F	Contig54	Nmar1418	COG0284	114	6e-27
Uridylate kinase	F	Contig54	Nmar0314	COG0528	40	2e-04
Uridylate kinase	F	Contig54	Nmar1705	COG0528	147	6e-37
Uridylate kinase	F	Contig54	Nmar1754	COG0528	46	6e-06

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	F	Contig54	Nmar1400	COG2065	34	0.008

PYRIMIDINE SALVAGE

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Cytidine deaminase	F	Contig54	Nmar1471	COG0295	76	6e-16
Cytosine deaminase and related metal-dependent hydrolase	F	Contig54	Nmar0214	COG0402	43	5e-05
Cytosine deaminase and related metal-dependent hydrolase	F	Contig54	Nmar1578	COG0402	49	8e-07
Cytosine deaminase and related metal-dependent hydrolase	F	Contig54	Nmar1613	COG0402	182	4e-47
Thymidine kinase	F	Contig54	Nmar0665	COG1435	36	0.008
Thymidine phosphorylase	F	Contig54	Nmar0913	COG0213	52	6e-08
Uracil phosphoribosyltransferase	F	Contig54	Nmar1774	COG0035	36	0.003

THIAMINE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Uncharacterized protein of thiazole biosynthesis	F	Contig54	Nmar1479	COG2022	44	1e-05

THYMIDYLATE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Nucleoside diphosphate kinase	F	Contig54	Nmar0228	COG0105	177	3e-46
Oxygen-sensitive ribonucleoside-triphosphate reductase	F	Contig54	Nmar1627	COG1328	66	1e-11
Oxygen-sensitive ribonucleoside-triphosphate reductase	F	Contig54	Nmar1628	COG1328	82	1e-16
Ribonucleotide reductase alpha subunit	F	Contig54	Nmar1627	COG0209	392	1.0e-110
Thymidylate kinase	F	Contig54	Nmar0531	COG0125	36	0.007
Thymidylate kinase	F	Contig54	Nmar1707	COG0125	123	7e-30
Thymidylate kinase	F	Contig54	Nmar1780	COG0125	34	0.007

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Xanthosine triphosphate pyrophosphatase	F	Contig54	Nmar1530	COG0127	156	9e-40

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