Lipid Metabolism

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
1-acyl-sn-glycerol-3-phosphate acyltransferase	I	Contig13	Neut1866	COG0204	108	3e-25
1-acyl-sn-glycerol-3-phosphate acyltransferase	I	Contig13	Neut1950	COG0204	89	3e-19
1-acyl-sn-glycerol-3-phosphate acyltransferase	I	Contig13	Neut2466	COG0204	94	7e-20
3-hydroxy-3-methylglutaryl CoA synthase	I	Contig13	Neut0470	COG3425	105	5e-24
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig13	Neut0226	COG2084	40	3e-04
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig13	Neut0433	COG2084	44	2e-05
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig13	Neut1093	COG2084	41	2e-04
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig13	Neut1260	COG2084	47	2e-06
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig13	Neut1568	COG2084	38	0.001
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig13	Neut1571	COG2084	43	4e-05
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig13	Neut1881	COG2084	276	1e-75
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig13	Neut2144	COG2084	116	2e-27
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig13	Neut2148	COG2084	48	8e-07
3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase	I	Contig13	Neut2432	COG2084	101	7e-23
3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	I	Contig13	Neut2025	COG0764	166	4e-43
Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	I	Contig13	Neut1154	COG4799	65	5e-12
Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	I	Contig13	Neut2398	COG4799	80	2e-16
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig13	Neut0455	COG4770	75	4e-14
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig13	Neut1201	COG4770	44	2e-05
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig13	Neut1211	COG4770	58	2e-09
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig13	Neut1401	COG4770	48	2e-06
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig13	Neut1402	COG4770	45	2e-05
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig13	Neut1609	COG4770	41	2e-04
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig13	Neut1899	COG4770	599	1.0e-172
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig13	Neut1900	COG4770	49	2e-07
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig13	Neut2103	COG4770	47	4e-06
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig13	Neut2116	COG4770	37	0.002
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig13	Neut2470	COG4770	550	1.0e-157
Acetyl/propionyl-CoA carboxylase alpha subunit	I	Contig13	Neut2475	COG4770	66	1e-11
Acyl carrier protein phosphodiesterase	I	Contig13	Neut2455	COG1182	38	4e-04
Acyl-CoA dehydrogenase	I	Contig13	Neut0703	COG1960	189	6e-49
Acyl-CoA hydrolase	I	Contig13	Neut0285	COG1607	34	0.004
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig13	Neut0458	COG0365	159	5e-40
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig13	Neut0702	COG0365	152	8e-38
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig13	Neut1097	COG0365	51	1e-07
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig13	Neut1417	COG0365	260	1e-70
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig13	Neut1690	COG0365	651	0.0
Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	I	Contig13	Neut2466	COG0365	183	5e-47
CDP-diglyceride synthetase	I	Contig13	Neut2030	COG0575	115	4e-27
Cytidylyltransferase	I	Contig13	Neut2341	COG0615	40	7e-05

DEOXYXYLULOSE PATHWAY OF TERPENOID BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
1-deoxy-D-xylulose 5-phosphate reductoisomerase	I	Contig13	Neut0865	COG0743	42	7e-05
1-deoxy-D-xylulose 5-phosphate reductoisomerase	I	Contig13	Neut2029	COG0743	554	1.0e-159
2C-methyl-D-erythritol 2 4-cyclodiphosphate synthase	I	Contig13	Neut1300	COG0245	213	4e-57
4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase	I	Contig13	Neut0157	COG1947	36	0.003
4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase	I	Contig13	Neut1139	COG1947	284	6e-78
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig13	Neut0159	COG1211	38	8e-04
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig13	Neut0268	COG1211	44	1e-05
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig13	Neut0279	COG1211	59	8e-10
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig13	Neut0618	COG1211	37	0.003
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig13	Neut1101	COG1211	41	1e-04
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig13	Neut1525	COG1211	227	4e-61
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig13	Neut1548	COG1211	37	0.001
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig13	Neut1880	COG1211	46	2e-06
4-diphosphocytidyl-2-methyl-D-erithritol synthase	I	Contig13	Neut2374	COG1211	41	1e-04
Deoxyxylulose-5-phosphate synthase	I	Contig13	Neut1501	COG1154	926	0.0
Deoxyxylulose-5-phosphate synthase	I	Contig13	Neut1577	COG1154	65	2e-11

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis	I	Contig13	Neut2168	COG0821	436	1.0e-123
Esterase/lipase	I	Contig13	Neut1386	COG0657	38	9e-04
Esterase/lipase	I	Contig13	Neut1627	COG0657	36	0.002

FATTY ACID BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
3-hydroxyacyl-CoA dehydrogenase	I	Contig13	Neut0724	COG1250	234	2e-62
3-hydroxyacyl-CoA dehydrogenase	I	Contig13	Neut1534	COG1250	36	0.003
3-hydroxyacyl-CoA dehydrogenase	I	Contig13	Neut1568	COG1250	41	7e-05
3-oxoacyl-(acyl-carrier-protein) synthase	I	Contig13	Neut0466	COG0304	495	1.0e-141
3-oxoacyl-(acyl-carrier-protein) synthase	I	Contig13	Neut0610	COG0304	53	5e-08
3-oxoacyl-(acyl-carrier-protein) synthase	I	Contig13	Neut0725	COG0304	45	8e-06
3-oxoacyl-(acyl-carrier-protein) synthase	I	Contig13	Neut2003	COG0304	200	2e-52
Acetyl-CoA acetyltransferase	I	Contig13	Neut0470	COG0183	41	1e-04
Acetyl-CoA acetyltransferase	I	Contig13	Neut0610	COG0183	318	5e-88
Acetyl-CoA acetyltransferase	I	Contig13	Neut0725	COG0183	308	3e-85
Acetyl-CoA acetyltransferase	I	Contig13	Neut2003	COG0183	41	4e-04
Acetyl-CoA carboxylase alpha subunit	I	Contig13	Neut2398	COG0825	480	1.0e-137
Acetyl-CoA carboxylase beta subunit	I	Contig13	Neut1154	COG0777	422	1.0e-119
Acyl carrier protein	I	Contig13	Neut0460	COG0236	45	1e-06
Acyl carrier protein	I	Contig13	Neut0467	COG0236	61	1e-11
(acyl-carrier-protein) S-malonyltransferase	I	Contig13	Neut0469	COG0331	329	1e-91
(acyl-carrier-protein) S-malonyltransferase	I	Contig13	Neut2003	COG0331	88	1e-18
Biotin carboxylase	I	Contig13	Neut0243	COG0439	67	2e-12
Biotin carboxylase	I	Contig13	Neut0455	COG0439	95	3e-20
Biotin carboxylase	I	Contig13	Neut0904	COG0439	58	8e-10
Biotin carboxylase	I	Contig13	Neut1201	COG0439	60	3e-10
Biotin carboxylase	I	Contig13	Neut1211	COG0439	61	1e-10
Biotin carboxylase	I	Contig13	Neut1401	COG0439	67	4e-12
Biotin carboxylase	I	Contig13	Neut1402	COG0439	56	9e-09
Biotin carboxylase	I	Contig13	Neut1899	COG0439	612	1.0e-176
Biotin carboxylase	I	Contig13	Neut2116	COG0439	46	3e-06
Biotin carboxylase	I	Contig13	Neut2470	COG0439	496	1.0e-141
Biotin carboxyl carrier protein	I	Contig13	Neut0859	COG0511	48	2e-06
Biotin carboxyl carrier protein	I	Contig13	Neut1562	COG0511	35	0.009
Biotin carboxyl carrier protein	I	Contig13	Neut1609	COG0511	47	4e-06
Biotin carboxyl carrier protein	I	Contig13	Neut1900	COG0511	108	1e-25
Biotin carboxyl carrier protein	I	Contig13	Neut2103	COG0511	50	4e-07
Biotin carboxyl carrier protein	I	Contig13	Neut2470	COG0511	73	1e-13
Biotin carboxyl carrier protein	I	Contig13	Neut2475	COG0511	74	4e-14
Enoyl-CoA hydratase/carnithine racemase	I	Contig13	Neut0724	COG1024	67	4e-12

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Fatty acid desaturase	I	Contig13	Neut0266	COG3239	47	2e-06
Fatty acid desaturase	I	Contig13	Neut0637	COG3239	64	2e-11
Fatty-acid desaturase	I	Contig13	Neut0779	COG1398	272	4e-74
Fatty acid desaturase	I	Contig13	Neut1694	COG3239	105	4e-24
Fatty acid/phospholipid biosynthesis enzyme	I	Contig13	Neut0471	COG0416	415	1.0e-117
Long-chain acyl-CoA synthetase (AMP-forming)	I	Contig13	Neut0458	COG1022	161	1e-40
Long-chain acyl-CoA synthetase (AMP-forming)	I	Contig13	Neut0702	COG1022	495	1.0e-141
Long-chain acyl-CoA synthetase (AMP-forming)	I	Contig13	Neut1417	COG1022	209	4e-55
Long-chain acyl-CoA synthetase (AMP-forming)	I	Contig13	Neut1690	COG1022	135	7e-33
Long-chain acyl-CoA synthetase (AMP-forming)	I	Contig13	Neut2466	COG1022	148	2e-36
Long-chain fatty acid transport protein	I	Contig13	Neut2467	COG2067	41	3e-04
Lysophospholipase	I	Contig13	Neut0959	COG2267	41	1e-04
Lysophospholipase	I	Contig13	Neut1627	COG2267	43	1e-05
Lysophospholipase	I	Contig13	Neut2064	COG2267	57	1e-09
Lysophospholipase	I	Contig13	Neut2107	COG2267	50	2e-07
Lysophospholipase	I	Contig13	Neut2108	COG2267	41	1e-04
Lysophospholipase	I	Contig13	Neut2133	COG2267	37	0.001
Lysophospholipase	I	Contig13	Neut2136	COG2267	69	5e-13
Lysophospholipase	I	Contig13	Neut2196	COG2267	52	5e-08
Lysophospholipase	I	Contig13	Neut2408	COG2267	47	2e-06

MENAQUINONE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig13	Neut0458	COG0318	277	1e-75
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig13	Neut0702	COG0318	267	2e-72
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig13	Neut1097	COG0318	51	2e-07
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig13	Neut1417	COG0318	352	3e-98
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig13	Neut1690	COG0318	287	1e-78
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	I	Contig13	Neut2466	COG0318	284	2e-77

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Methylmalonyl-CoA mutase C-terminal domain/subunit (cobalamin-binding)	I	Contig13	Neut0500	COG2185	51	7e-07
Mevalonate kinase	I	Contig13	Neut0157	COG1577	109	2e-25
Oligoketide cyclase/lipid transport protein	I	Contig13	Neut0586	COG2867	153	7e-39
Penicillin tolerance protein	I	Contig13	Neut1903	COG0761	405	1.0e-114
Phosphatidylglycerophosphatase A and related protein	I	Contig13	Neut2520	COG1267	116	1e-27
Phosphatidylglycerophosphate synthase	I	Contig13	Neut1104	COG0558	57	3e-09
Phosphatidylglycerophosphate synthase	I	Contig13	Neut1258	COG0558	41	1e-04
Phosphatidylglycerophosphate synthase	I	Contig13	Neut2079	COG0558	110	6e-26
Phosphatidylserine decarboxylase	I	Contig13	Neut1259	COG0688	198	3e-52
Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase	I	Contig13	Neut0328	COG1502	275	3e-75
Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase	I	Contig13	Neut0834	COG1502	64	2e-11
Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase	I	Contig13	Neut1890	COG1502	52	4e-08
Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase	I	Contig13	Neut2297	COG1502	197	9e-52
Phosphatidylserine synthase	I	Contig13	Neut1104	COG1183	39	5e-04
Phosphatidylserine synthase	I	Contig13	Neut1258	COG1183	184	5e-48
Phospholipase/lecithinase/hemolysin	I	Contig13	Neut0534	COG3240	129	4e-31
Phospholipid N-methyltransferase	I	Contig13	Neut1219	COG3963	36	0.003
Phosphopantetheinyl transferase (holo-ACP synthase)	I	Contig13	Neut1775	COG0736	137	2e-34
Phytoene/squalene synthetase	I	Contig13	Neut0403	COG1562	114	1e-26
Poly(3-hydroxyalkanoate) synthetase	I	Contig13	Neut0052	COG3243	36	0.007
sn-1 2-diacylglycerol ethanolamine- and cholinephosphotranferase	I	Contig13	Neut1104	COG5050	38	0.001
Sphingosine kinase	I	Contig13	Neut1105	COG1597	65	9e-12
Squalene cyclase	I	Contig13	Neut1507	COG1657	231	2e-61
Undecaprenyl pyrophosphate synthase	I	Contig13	Neut2031	COG0020	305	2e-84

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