Nucleotide Transport and Metabolism

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase	F	AL954747	NE1390	COG0737	37	0.004
Adenine deaminase	F	AL954747	NE1664	COG1001	44	2e-05
Adenine deaminase	F	AL954747	NE2343	COG1001	48	2e-06
Adenosine deaminase	F	AL954747	NE0722	COG2169	41	2e-04
Adenosine deaminase	F	AL954747	NE2507	COG2169	46	3e-06
Adenosine deaminase	F	AL954747	NE2511	COG2169	46	5e-06
ADP-ribose pyrophosphatase	F	AL954747	NE0184	COG1051	56	1e-09
ADP-ribose pyrophosphatase	F	AL954747	NE1158	COG1051	107	4e-25
ADP-ribose pyrophosphatase	F	AL954747	NE1316	COG1051	49	2e-07
ADP-ribose pyrophosphatase	F	AL954747	NE2215	COG1051	59	6e-10
ADP-ribose pyrophosphatase	F	AL954747	NE2253	COG1051	49	2e-07
Cytosine/adenosine deaminase	F	AL954747	NE0047	COG0590	79	2e-16
Cytosine/adenosine deaminase	F	AL954747	NE0437	COG0590	174	2e-45
Cytosine/adenosine deaminase	F	AL954747	NE0793	COG0590	74	2e-14
Cytosine/uracil/thiamine/allantoin permease	F	AL954747	NE0168	COG1953	41	5e-04
Deoxycytidylate deaminase	F	AL954747	NE0437	COG2131	54	5e-09
Deoxycytidylate deaminase	F	AL954747	NE0793	COG2131	66	5e-12
Deoxynucleoside kinase	F	AL954747	NE0071	COG1428	152	2e-38
dGTP triphosphohydrolase	F	AL954747	NE1982	COG0232	352	2e-98
Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase	F	AL954747	NE0176	COG0537	62	2e-11
Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase	F	AL954747	NE0640	COG0537	115	1e-27
Exopolyphosphatase	F	AL954747	NE1745	COG0248	395	1.0e-111
Guanylate kinase	F	AL954747	NE2254	COG0194	238	2e-64
Guanylate kinase	F	AL954747	NE2384	COG0194	36	0.003
Orotate phosphoribosyltransferase homologs	F	AL954747	NE0181	COG0856	47	6e-07
Orotate phosphoribosyltransferase homologs	F	AL954747	NE0699	COG0856	47	3e-06
Orotate phosphoribosyltransferase homologs	F	AL954747	NE1734	COG0856	49	3e-07
Orotate phosphoribosyltransferase homologs	F	AL954747	NE1826	COG0856	41	1e-04
Orotate phosphoribosyltransferase homologs	F	AL954747	NE2301	COG0856	46	2e-06
Predicted nucleotide kinase	F	AL954747	NE0071	COG4088	39	3e-04
Predicted nucleotide kinase (related to CMP and AMP kinase)	F	AL954747	NE0071	COG1936	35	0.004

PURINE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Adenylosuccinate lyase	F	AL954747	NE1854	COG0015	126	2e-30
Adenylosuccinate lyase	F	AL954747	NE1951	COG0015	359	1.0e-100
Adenylosuccinate lyase	F	AL954747	NE2286	COG0015	106	3e-24
Adenylosuccinate synthase	F	AL954747	NE1281	COG0104	643	0.0
AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)	F	AL954747	NE0876	COG0138	763	0.0
AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)	F	AL954747	NE1661	COG0138	51	4e-07
Folate-dependent phosphoribosylglycinamide formyltransferase PurN	F	AL954747	NE0087	COG0299	265	2e-72
Folate-dependent phosphoribosylglycinamide formyltransferase PurN	F	AL954747	NE1971	COG0299	85	8e-18
Folate-dependent phosphoribosylglycinamide formyltransferase PurN	F	AL954747	NE2171	COG0299	88	6e-19
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	AL954747	NE0653	COG0027	48	1e-06
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	AL954747	NE0867	COG0027	136	2e-33
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	AL954747	NE0922	COG0027	39	0.001
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	AL954747	NE0994	COG0027	39	4e-04
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	AL954747	NE1661	COG0027	53	1e-07
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	AL954747	NE2420	COG0027	38	0.005
Glutamine phosphoribosylpyrophosphate amidotransferase	F	AL954747	NE0181	COG0034	36	0.001
Glutamine phosphoribosylpyrophosphate amidotransferase	F	AL954747	NE0209	COG0034	138	1e-33
Glutamine phosphoribosylpyrophosphate amidotransferase	F	AL954747	NE0699	COG0034	609	1.0e-175
Glutamine phosphoribosylpyrophosphate amidotransferase	F	AL954747	NE1795	COG0034	76	1e-14
Glutamine phosphoribosylpyrophosphate amidotransferase	F	AL954747	NE2301	COG0034	43	2e-05
GMP synthase - Glutamine amidotransferase domain	F	AL954747	NE0014	COG0518	86	2e-18
GMP synthase - Glutamine amidotransferase domain	F	AL954747	NE0094	COG0518	215	7e-57
GMP synthase - Glutamine amidotransferase domain	F	AL954747	NE0585	COG0518	143	1e-35
GMP synthase - Glutamine amidotransferase domain	F	AL954747	NE0645	COG0518	55	4e-09
GMP synthase - Glutamine amidotransferase domain	F	AL954747	NE1662	COG0518	74	2e-14
GMP synthase PP-ATPase domain/subunit	F	AL954747	NE0094	COG0519	541	1.0e-155
GMP synthase PP-ATPase domain/subunit	F	AL954747	NE0963	COG0519	47	2e-06
IMP dehydrogenase/GMP reductase	F	AL954747	NE0095	COG0516	138	1e-33
Phosphoribosylamine-glycine ligase	F	AL954747	NE0050	COG0151	39	8e-04
Phosphoribosylamine-glycine ligase	F	AL954747	NE0653	COG0151	55	1e-08
Phosphoribosylamine-glycine ligase	F	AL954747	NE0877	COG0151	565	1.0e-162
Phosphoribosylamine-glycine ligase	F	AL954747	NE0922	COG0151	55	2e-08
Phosphoribosylamine-glycine ligase	F	AL954747	NE0923	COG0151	49	1e-06
Phosphoribosylamine-glycine ligase	F	AL954747	NE1661	COG0151	55	3e-08
Phosphoribosylamine-glycine ligase	F	AL954747	NE1810	COG0151	39	5e-04
Phosphoribosylamine-glycine ligase	F	AL954747	NE2270	COG0151	51	2e-07
Phosphoribosylaminoimidazole (AIR) synthetase	F	AL954747	NE0088	COG0150	483	1.0e-138
Phosphoribosylaminoimidazole (AIR) synthetase	F	AL954747	NE2559	COG0150	39	4e-04
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	AL954747	NE0653	COG0026	71	2e-13
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	AL954747	NE0867	COG0026	427	1.0e-121
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	AL954747	NE0922	COG0026	52	1e-07
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	AL954747	NE0923	COG0026	40	6e-04
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	AL954747	NE0994	COG0026	45	7e-06
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	AL954747	NE1661	COG0026	50	8e-07
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	AL954747	NE1792	COG0026	49	4e-07
Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase	F	AL954747	NE0866	COG0152	222	3e-59
Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	F	AL954747	NE0868	COG0041	220	6e-59
Phosphoribosylformylglycinamidine (FGAM) synthase glutamine amidotransferase domain	F	AL954747	NE0019	COG0047	257	4e-69
Phosphoribosylformylglycinamidine (FGAM) synthase glutamine amidotransferase domain	F	AL954747	NE0645	COG0047	36	0.002
Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain	F	AL954747	NE0019	COG0046	713	0.0
Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain	F	AL954747	NE0088	COG0046	44	2e-05
Phosphoribosylpyrophosphate synthetase	F	AL954747	NE0181	COG0462	39	2e-04
Phosphoribosylpyrophosphate synthetase	F	AL954747	NE0699	COG0462	38	0.002
Phosphoribosylpyrophosphate synthetase	F	AL954747	NE1826	COG0462	409	1.0e-115
Phosphoribosylpyrophosphate synthetase	F	AL954747	NE2301	COG0462	39	4e-04
Phosphoribosylpyrophosphate synthetase	F	AL954747	NE2520	COG0462	41	4e-04

PURINE SALVAGE

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	AL954747	NE0181	COG0503	180	5e-47
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	AL954747	NE0699	COG0503	42	1e-04
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	AL954747	NE1734	COG0503	46	1e-06
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	AL954747	NE1826	COG0503	39	4e-04
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	AL954747	NE2301	COG0503	43	3e-05
Formyltetrahydrofolate hydrolase	F	AL954747	NE0087	COG0788	140	9e-35
Formyltetrahydrofolate hydrolase	F	AL954747	NE1971	COG0788	48	9e-07
Formyltetrahydrofolate hydrolase	F	AL954747	NE2171	COG0788	57	1e-09
Hypoxanthine-guanine phosphoribosyltransferase	F	AL954747	NE0181	COG0634	34	0.005
Hypoxanthine-guanine phosphoribosyltransferase	F	AL954747	NE1666	COG0634	52	2e-08
Hypoxanthine-guanine phosphoribosyltransferase	F	AL954747	NE1826	COG0634	40	3e-04
Hypoxanthine-guanine phosphoribosyltransferase	F	AL954747	NE2301	COG0634	35	0.005
Purine nucleoside phosphorylase	F	AL954747	NE1754	COG0005	200	8e-53

PYRIMIDINE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Adenylate kinase and related kinase	F	AL954747	NE1933	COG0563	175	3e-45
Adenylate kinase and related kinase	F	AL954747	NE1963	COG0563	39	3e-04
Adenylate kinase and related kinase	F	AL954747	NE1980	COG0563	34	0.009
Aspartate carbamoyltransferase catalytic chain	F	AL954747	NE1438	COG0540	165	5e-42
Aspartate carbamoyltransferase catalytic chain	F	AL954747	NE1665	COG0540	350	8e-98
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	AL954747	NE0653	COG0458	81	2e-16
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	AL954747	NE0867	COG0458	52	8e-08
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	AL954747	NE0877	COG0458	42	1e-04
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	AL954747	NE0922	COG0458	60	6e-10
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	AL954747	NE0923	COG0458	50	8e-07
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	AL954747	NE0994	COG0458	53	3e-08
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	AL954747	NE1661	COG0458	570	1.0e-163
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	AL954747	NE1792	COG0458	55	6e-09
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	AL954747	NE2420	COG0458	64	9e-11
Carbamoylphosphate synthase small subunit	F	AL954747	NE0014	COG0505	84	6e-18
Carbamoylphosphate synthase small subunit	F	AL954747	NE0094	COG0505	52	1e-07
Carbamoylphosphate synthase small subunit	F	AL954747	NE0585	COG0505	49	4e-07
Carbamoylphosphate synthase small subunit	F	AL954747	NE0645	COG0505	36	0.003
Carbamoylphosphate synthase small subunit	F	AL954747	NE1045	COG0505	38	0.002
Carbamoylphosphate synthase small subunit	F	AL954747	NE1662	COG0505	539	1.0e-154
CTP synthase (UTP-ammonia lyase)	F	AL954747	NE0645	COG0504	36	0.002
CTP synthase (UTP-ammonia lyase)	F	AL954747	NE1045	COG0504	870	0.0
CTP synthase (UTP-ammonia lyase)	F	AL954747	NE1662	COG0504	42	9e-05
Cytidylate kinase	F	AL954747	NE1933	COG1102	36	0.003
Cytidylate kinase	F	AL954747	NE1963	COG1102	45	3e-06
Cytidylate kinase	F	AL954747	NE1963	COG0283	245	2e-66
Cytidylate kinase	F	AL954747	NE1980	COG1102	35	0.003
Dihydroorotase	F	AL954747	NE0727	COG0418	519	1.0e-148
Dihydroorotase and related cyclic amidohydrolase	F	AL954747	NE0727	COG0044	70	2e-13
Dihydroorotase and related cyclic amidohydrolase	F	AL954747	NE1664	COG0044	368	1.0e-103
Dihydroorotase and related cyclic amidohydrolase	F	AL954747	NE2343	COG0044	45	1e-05
Dihydroorotate dehydrogenase	F	AL954747	NE0095	COG0167	41	2e-04
Dihydroorotate dehydrogenase	F	AL954747	NE0874	COG0167	58	1e-09
Dihydroorotate dehydrogenase	F	AL954747	NE2126	COG0167	43	2e-05
Dihydroorotate dehydrogenase	F	AL954747	NE2221	COG0167	290	9e-80
Orotate phosphoribosyltransferase	F	AL954747	NE0181	COG0461	63	1e-11
Orotate phosphoribosyltransferase	F	AL954747	NE1666	COG0461	35	0.002
Orotate phosphoribosyltransferase	F	AL954747	NE1734	COG0461	161	3e-41
Orotate phosphoribosyltransferase	F	AL954747	NE1826	COG0461	39	5e-04
Orotate phosphoribosyltransferase	F	AL954747	NE2301	COG0461	46	3e-06
Orotidine-5'-phosphate decarboxylase	F	AL954747	NE1959	COG0284	237	4e-64
Uridylate kinase	F	AL954747	NE1290	COG0528	64	2e-11
Uridylate kinase	F	AL954747	NE1716	COG0528	294	5e-81
Uridylate kinase	F	AL954747	NE2132	COG0528	63	5e-11

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	F	AL954747	NE1666	COG2065	157	4e-40

PYRIMIDINE SALVAGE

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Cytosine deaminase and related metal-dependent hydrolase	F	AL954747	NE1664	COG0402	43	4e-05
Cytosine deaminase and related metal-dependent hydrolase	F	AL954747	NE2343	COG0402	50	3e-07
Nucleoside phosphorylase	F	AL954747	NE1167	COG0775	70	1e-13
Purine-nucleoside phosphorylase	F	AL954747	NE1167	COG0813	47	1e-06
Thymidine phosphorylase	F	AL954747	NE0013	COG0213	58	1e-09
Uracil phosphoribosyltransferase	F	AL954747	NE0181	COG0035	36	0.002
Uracil phosphoribosyltransferase	F	AL954747	NE1666	COG0035	40	8e-05
Uridine kinase	F	AL954747	NE1474	COG0572	51	7e-08
Uridine kinase	F	AL954747	NE2384	COG0572	35	0.005

THIAMINE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Uncharacterized protein of thiazole biosynthesis	F	AL954747	NE0284	COG2022	357	1.0e-100

THYMIDYLATE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Deoxycytidine deaminase	F	AL954747	NE0623	COG0717	212	1e-56
Deoxycytidine deaminase	F	AL954747	NE1462	COG0717	46	9e-07
dUTPase	F	AL954747	NE1462	COG0756	175	9e-46
Nucleoside diphosphate kinase	F	AL954747	NE0144	COG0105	198	1e-52
Oxygen-sensitive ribonucleoside-triphosphate reductase	F	AL954747	NE2423	COG1328	56	8e-09
Ribonucleotide reductase alpha subunit	F	AL954747	NE2423	COG0209	581	1.0e-166
Ribonucleotide reductase beta subunit	F	AL954747	NE2422	COG0208	350	9e-98
Thymidylate kinase	F	AL954747	NE0071	COG0125	56	2e-09
Thymidylate kinase	F	AL954747	NE1899	COG0125	34	0.007
Thymidylate kinase	F	AL954747	NE2181	COG0125	218	2e-58
Thymidylate synthase	F	AL954747	NE0568	COG0207	408	1.0e-115

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Xanthine/uracil permease	F	AL954747	NE1927	COG2233	36	0.010
Xanthosine triphosphate pyrophosphatase	F	AL954747	NE0277	COG0127	236	1e-63

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