Nucleotide Transport and Metabolism

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Adenine deaminase	F	BX950229	MMP0509	COG1001	50	5e-07
Adenine deaminase	F	BX950229	MMP1009	COG1001	53	5e-08
Adenine deaminase	F	BX950229	MMP1248	COG1001	43	6e-05
Adenine deaminase	F	BX950229	MMP1380	COG1001	43	4e-05
Adenine deaminase	F	BX950229	MMP1491	COG1001	42	8e-05
Adenosine deaminase	F	BX950229	MMP1380	COG1816	48	9e-07
Adenylate cyclase class 2 (thermophilic)	F	BX950229	MMP1064	COG1437	137	4e-34
adenylate kinase	F	BX950229	MMP1031	COG2019	215	1e-57
adenylate kinase	F	BX950229	MMP1282	COG2019	35	0.005
ADP-ribose pyrophosphatase	F	BX950229	MMP0339	COG1051	129	1e-31
Aspartate carbamoyltransferase regulatory subunit	F	BX950229	MMP1104	COG1781	157	3e-40
Cytosine/adenosine deaminase	F	BX950229	MMP0869	COG0590	113	4e-27
Cytosine/uracil/thiamine/allantoin permease	F	BX950229	MMP0789	COG1953	91	1e-19
Deoxycytidylate deaminase	F	BX950229	MMP0869	COG2131	52	2e-08
Deoxynucleoside kinase	F	BX950229	MMP0626	COG1428	36	0.001
Deoxynucleoside kinase	F	BX950229	MMP1034	COG1428	52	2e-08
Deoxyribose-phosphate aldolase	F	BX950229	MMP0708	COG0274	36	0.002
dGTP triphosphohydrolase	F	BX950229	MMP0174	COG0232	46	4e-06
Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase	F	BX950229	MMP0331	COG0537	135	2e-33
Guanylate kinase	F	BX950229	MMP0229	COG0194	35	0.004
IMP cyclohydrolase	F	BX950229	MMP1310	COG3363	222	1e-59
Orotate phosphoribosyltransferase homologs	F	BX950229	MMP0079	COG0856	167	5e-43
Orotate phosphoribosyltransferase homologs	F	BX950229	MMP0145	COG0856	45	3e-06
Orotate phosphoribosyltransferase homologs	F	BX950229	MMP0410	COG0856	40	2e-04
Orotate phosphoribosyltransferase homologs	F	BX950229	MMP0660	COG0856	44	7e-06
Orotate phosphoribosyltransferase homologs	F	BX950229	MMP1492	COG0856	44	7e-06
Predicted nucleotide kinase	F	BX950229	MMP1490	COG4088	168	3e-43
Predicted nucleotide kinase (related to CMP and AMP kinase)	F	BX950229	MMP0626	COG1936	44	7e-06
Predicted nucleotide kinase (related to CMP and AMP kinase)	F	BX950229	MMP1031	COG1936	37	0.001
Predicted nucleotide kinase (related to CMP and AMP kinase)	F	BX950229	MMP1034	COG1936	34	0.009
Predicted nucleotide kinase (related to CMP and AMP kinase)	F	BX950229	MMP1282	COG1936	38	6e-04
Predicted nucleotide kinase (related to CMP and AMP kinase)	F	BX950229	MMP1534	COG1936	101	2e-23

PURINE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Adenylosuccinate lyase	F	BX950229	MMP0013	COG0015	109	6e-25
Adenylosuccinate lyase	F	BX950229	MMP0971	COG0015	524	1.0e-150
Adenylosuccinate synthase	F	BX950229	MMP1432	COG0104	392	1.0e-110
AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)	F	BX950229	MMP1013	COG0138	44	5e-05
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	BX950229	MMP0123	COG0027	572	1.0e-164
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	BX950229	MMP0341	COG0027	55	1e-08
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	BX950229	MMP0392	COG0027	37	0.003
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	BX950229	MMP0436	COG0027	36	0.003
Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	F	BX950229	MMP1013	COG0027	61	6e-10
Glutamine phosphoribosylpyrophosphate amidotransferase	F	BX950229	MMP0079	COG0034	34	0.010
Glutamine phosphoribosylpyrophosphate amidotransferase	F	BX950229	MMP0080	COG0034	52	7e-08
Glutamine phosphoribosylpyrophosphate amidotransferase	F	BX950229	MMP0145	COG0034	35	0.003
Glutamine phosphoribosylpyrophosphate amidotransferase	F	BX950229	MMP0410	COG0034	42	7e-05
Glutamine phosphoribosylpyrophosphate amidotransferase	F	BX950229	MMP0918	COG0034	69	9e-13
Glutamine phosphoribosylpyrophosphate amidotransferase	F	BX950229	MMP1146	COG0034	632	0.0
Glutamine phosphoribosylpyrophosphate amidotransferase	F	BX950229	MMP1680	COG0034	133	3e-32
GMP synthase - Glutamine amidotransferase domain	F	BX950229	MMP0256	COG0518	67	1e-12
GMP synthase - Glutamine amidotransferase domain	F	BX950229	MMP1005	COG0518	116	2e-27
GMP synthase - Glutamine amidotransferase domain	F	BX950229	MMP1082	COG0518	57	1e-09
GMP synthase - Glutamine amidotransferase domain	F	BX950229	MMP1445	COG0518	161	2e-41
GMP synthase - Glutamine amidotransferase domain	F	BX950229	MMP1589	COG0518	56	3e-09
GMP synthase - Glutamine amidotransferase domain	F	BX950229	MMP1656	COG0518	38	5e-04
GMP synthase PP-ATPase domain/subunit	F	BX950229	MMP0226	COG0519	42	4e-05
GMP synthase PP-ATPase domain/subunit	F	BX950229	MMP0661	COG0519	36	0.003
GMP synthase PP-ATPase domain/subunit	F	BX950229	MMP0894	COG0519	441	1.0e-125
GMP synthase PP-ATPase domain/subunit	F	BX950229	MMP1081	COG0519	39	4e-04
GMP synthase PP-ATPase domain/subunit	F	BX950229	MMP1239	COG0519	50	2e-07
GMP synthase PP-ATPase domain/subunit	F	BX950229	MMP1349	COG0519	41	7e-05
GMP synthase PP-ATPase domain/subunit	F	BX950229	MMP1356	COG0519	49	5e-07
GMP synthase PP-ATPase domain/subunit	F	BX950229	MMP1681	COG0519	49	9e-07
IMP dehydrogenase/GMP reductase	F	BX950229	MMP0133	COG0516	133	2e-32
Phosphoribosylamine-glycine ligase	F	BX950229	MMP0123	COG0151	54	2e-08
Phosphoribosylamine-glycine ligase	F	BX950229	MMP0253	COG0151	39	9e-04
Phosphoribosylamine-glycine ligase	F	BX950229	MMP0341	COG0151	79	8e-16
Phosphoribosylamine-glycine ligase	F	BX950229	MMP0392	COG0151	446	1.0e-126
Phosphoribosylamine-glycine ligase	F	BX950229	MMP1013	COG0151	60	1e-09
Phosphoribosylamine-glycine ligase	F	BX950229	MMP1105	COG0151	43	4e-05
Phosphoribosylaminoimidazole (AIR) synthetase	F	BX950229	MMP0274	COG0150	76	4e-15
Phosphoribosylaminoimidazole (AIR) synthetase	F	BX950229	MMP0291	COG0150	41	2e-04
Phosphoribosylaminoimidazole (AIR) synthetase	F	BX950229	MMP0904	COG0150	48	1e-06
Phosphoribosylaminoimidazole (AIR) synthetase	F	BX950229	MMP1124	COG0150	43	2e-05
Phosphoribosylaminoimidazole (AIR) synthetase	F	BX950229	MMP1254	COG0150	364	1.0e-102
Phosphoribosylaminoimidazole (AIR) synthetase	F	BX950229	MMP1531	COG0150	52	4e-08
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	BX950229	MMP0123	COG0026	218	5e-58
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	BX950229	MMP0170	COG0026	42	6e-05
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	BX950229	MMP0341	COG0026	66	7e-12
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	BX950229	MMP0436	COG0026	38	0.001
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	BX950229	MMP0702	COG0026	42	5e-05
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	BX950229	MMP1013	COG0026	56	1e-08
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	F	BX950229	MMP1600	COG0026	43	2e-05
Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase	F	BX950229	MMP0540	COG0152	262	2e-71
Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	F	BX950229	MMP0282	COG0041	187	3e-49
Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	F	BX950229	MMP0809	COG0041	45	6e-06
Phosphoribosylformylglycinamidine (FGAM) synthase glutamine amidotransferase domain	F	BX950229	MMP0028	COG0047	37	0.004
Phosphoribosylformylglycinamidine (FGAM) synthase glutamine amidotransferase domain	F	BX950229	MMP0178	COG0047	219	1e-58
Phosphoribosylformylglycinamidine (FGAM) synthase glutamine amidotransferase domain	F	BX950229	MMP0559	COG0047	35	0.004
Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain	F	BX950229	MMP0179	COG0046	531	1.0e-152
Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain	F	BX950229	MMP0274	COG0046	82	7e-17
Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain	F	BX950229	MMP0291	COG0046	54	2e-08
Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain	F	BX950229	MMP0882	COG0046	71	1e-13
Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain	F	BX950229	MMP0904	COG0046	38	0.001
Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain	F	BX950229	MMP1124	COG0046	38	0.001
Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain	F	BX950229	MMP1254	COG0046	46	6e-06
Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain	F	BX950229	MMP1531	COG0046	59	4e-10
Phosphoribosylpyrophosphate synthetase	F	BX950229	MMP0079	COG0462	39	4e-04
Phosphoribosylpyrophosphate synthetase	F	BX950229	MMP0145	COG0462	47	9e-07
Phosphoribosylpyrophosphate synthetase	F	BX950229	MMP0410	COG0462	285	2e-78
Phosphoribosylpyrophosphate synthetase	F	BX950229	MMP0660	COG0462	37	0.001
Phosphoribosylpyrophosphate synthetase	F	BX950229	MMP1146	COG0462	41	3e-04
Phosphoribosylpyrophosphate synthetase	F	BX950229	MMP1492	COG0462	40	1e-04

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Purine-cytosine permease and related protein	F	BX950229	MMP0789	COG1457	240	1e-64

PURINE SALVAGE

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	BX950229	MMP0079	COG0503	49	3e-07
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	BX950229	MMP0145	COG0503	119	1e-28
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	BX950229	MMP0410	COG0503	48	9e-07
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	BX950229	MMP0660	COG0503	166	1e-42
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	BX950229	MMP1146	COG0503	43	4e-05
Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein	F	BX950229	MMP1492	COG0503	57	7e-10
Formyltetrahydrofolate hydrolase	F	BX950229	MMP0400	COG0788	37	0.001
Formyltetrahydrofolate hydrolase	F	BX950229	MMP0657	COG0788	42	1e-05
Hypoxanthine-guanine phosphoribosyltransferase	F	BX950229	MMP0079	COG0634	37	0.001
Hypoxanthine-guanine phosphoribosyltransferase	F	BX950229	MMP0410	COG0634	50	3e-07
Hypoxanthine-guanine phosphoribosyltransferase	F	BX950229	MMP0680	COG0634	37	0.001
Purine nucleoside phosphorylase	F	BX950229	MMP0185	COG0005	250	8e-68

PYRIMIDINE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Adenylate kinase and related kinase	F	BX950229	MMP0626	COG0563	46	1e-06
Adenylate kinase and related kinase	F	BX950229	MMP1034	COG0563	37	0.001
Aspartate carbamoyltransferase catalytic chain	F	BX950229	MMP0553	COG0540	172	3e-44
Aspartate carbamoyltransferase catalytic chain	F	BX950229	MMP1659	COG0540	387	1.0e-109
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	BX950229	MMP0035	COG0458	45	1e-05
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	BX950229	MMP0123	COG0458	60	3e-10
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	BX950229	MMP0170	COG0458	56	3e-09
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	BX950229	MMP0341	COG0458	121	1e-28
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	BX950229	MMP0392	COG0458	39	6e-04
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	BX950229	MMP0436	COG0458	57	2e-09
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	BX950229	MMP1013	COG0458	555	1.0e-159
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	BX950229	MMP1105	COG0458	46	5e-06
Carbamoylphosphate synthase large subunit (split gene in MJ)	F	BX950229	MMP1600	COG0458	42	4e-05
Carbamoylphosphate synthase small subunit	F	BX950229	MMP0893	COG0505	40	5e-04
Carbamoylphosphate synthase small subunit	F	BX950229	MMP1005	COG0505	94	9e-21
Carbamoylphosphate synthase small subunit	F	BX950229	MMP1082	COG0505	39	2e-04
Carbamoylphosphate synthase small subunit	F	BX950229	MMP1445	COG0505	73	1e-14
Carbamoylphosphate synthase small subunit	F	BX950229	MMP1589	COG0505	481	1.0e-137
CTP synthase (UTP-ammonia lyase)	F	BX950229	MMP0256	COG0504	36	0.002
CTP synthase (UTP-ammonia lyase)	F	BX950229	MMP0893	COG0504	881	0.0
Cytidylate kinase	F	BX950229	MMP0626	COG1102	219	9e-59
Cytidylate kinase	F	BX950229	MMP0626	COG0283	37	9e-04
Cytidylate kinase	F	BX950229	MMP1031	COG1102	41	7e-05
Cytidylate kinase	F	BX950229	MMP1034	COG1102	37	0.001
Cytidylate kinase	F	BX950229	MMP1282	COG1102	37	8e-04
Dihydroorotase and related cyclic amidohydrolase	F	BX950229	MMP0509	COG0044	61	2e-10
Dihydroorotase and related cyclic amidohydrolase	F	BX950229	MMP1009	COG0044	390	1.0e-109
Dihydroorotase and related cyclic amidohydrolase	F	BX950229	MMP1248	COG0044	50	4e-07
Dihydroorotase and related cyclic amidohydrolase	F	BX950229	MMP1491	COG0044	67	2e-12
Dihydroorotase	F	BX950229	MMP1009	COG0418	58	1e-09
Dihydroorotate dehydrogenase	F	BX950229	MMP0007	COG0167	38	0.001
Dihydroorotate dehydrogenase	F	BX950229	MMP0081	COG0167	56	5e-09
Dihydroorotate dehydrogenase	F	BX950229	MMP0133	COG0167	46	8e-06
Dihydroorotate dehydrogenase	F	BX950229	MMP0439	COG0167	297	6e-82
Dihydroorotate dehydrogenase	F	BX950229	MMP1083	COG0167	37	0.001
Orotate phosphoribosyltransferase	F	BX950229	MMP0079	COG0461	57	1e-09
Orotate phosphoribosyltransferase	F	BX950229	MMP0145	COG0461	74	7e-15
Orotate phosphoribosyltransferase	F	BX950229	MMP0410	COG0461	39	3e-04
Orotate phosphoribosyltransferase	F	BX950229	MMP0660	COG0461	47	7e-07
Orotate phosphoribosyltransferase	F	BX950229	MMP1492	COG0461	164	3e-42
Orotidine-5'-phosphate decarboxylase	F	BX950229	MMP0602	COG0284	158	3e-40
Orotidine-5'-phosphate decarboxylase	F	BX950229	MMP1270	COG0284	61	2e-10
Uridylate kinase	F	BX950229	MMP0385	COG0528	191	3e-50
Uridylate kinase	F	BX950229	MMP1017	COG0528	50	4e-07
Uridylate kinase	F	BX950229	MMP1399	COG0528	54	7e-09
Uridylate kinase	F	BX950229	MMP1645	COG0528	57	2e-09

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	F	BX950229	MMP0079	COG2065	41	6e-05

PYRIMIDINE SALVAGE

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Cytosine deaminase and related metal-dependent hydrolase	F	BX950229	MMP0378	COG0402	283	2e-77
Cytosine deaminase and related metal-dependent hydrolase	F	BX950229	MMP0509	COG0402	52	9e-08
Cytosine deaminase and related metal-dependent hydrolase	F	BX950229	MMP1009	COG0402	54	2e-08
Cytosine deaminase and related metal-dependent hydrolase	F	BX950229	MMP1248	COG0402	41	2e-04
Cytosine deaminase and related metal-dependent hydrolase	F	BX950229	MMP1380	COG0402	179	4e-46
Cytosine deaminase and related metal-dependent hydrolase	F	BX950229	MMP1491	COG0402	327	1e-90
Thymidine phosphorylase	F	BX950229	MMP0327	COG0213	406	1.0e-114
Thymidine phosphorylase	F	BX950229	MMP1007	COG0213	52	5e-08
Uracil phosphoribosyltransferase	F	BX950229	MMP0680	COG0035	211	3e-56

THIAMINE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Uncharacterized protein of thiazole biosynthesis	F	BX950229	MMP0103	COG2022	44	2e-05
Uncharacterized protein of thiazole biosynthesis	F	BX950229	MMP1690	COG2022	39	2e-04

THYMIDYLATE BIOSYNTHESIS

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Deoxycytidine deaminase	F	BX950229	MMP1075	COG0717	104	4e-24
Deoxycytidine deaminase	F	BX950229	MMP1426	COG0717	146	1e-36
dUTPase	F	BX950229	MMP1426	COG0756	45	4e-06
Nucleoside diphosphate kinase	F	BX950229	MMP0283	COG0105	186	8e-49
Oxygen-sensitive ribonucleoside-triphosphate reductase	F	BX950229	MMP0227	COG1328	622	1.0e-179
Oxygen-sensitive ribonucleoside-triphosphate reductase	F	BX950229	MMP1160	COG1328	35	0.002
Thymidylate kinase	F	BX950229	MMP1031	COG0125	34	0.007
Thymidylate kinase	F	BX950229	MMP1034	COG0125	156	1e-39
Thymidylate synthase	F	BX950229	MMP1379	COG0207	140	9e-35

COG Name	Group	Contig	Gene	COG ID	Score	Evalue
Xanthine/uracil permease	F	BX950229	MMP0529	COG2233	55	1e-08
Xanthine/uracil permease	F	BX950229	MMP0663	COG2233	66	7e-12
Xanthine/uracil permease	F	BX950229	MMP0681	COG2233	284	6e-78
Xanthine/uracil permease	F	BX950229	MMP0689	COG2233	49	6e-07
Xanthosine triphosphate pyrophosphatase	F	BX950229	MMP0214	COG0127	176	9e-46

SiteMap Feedback Life Sciences Division ORNL Disclaimer Webmaster