KEGG Metabolic Pathways with PRIAM on species complete genome
Graphical pathway maps


PRIAM prediction above cutoff value
PRIAM prediction below cutoff value
EC without proteins in ENZYME
no information


KEGG PATHWAY is a collection of manually drawn pathway maps representing our knowledge on the molecular interaction and reaction networks for:
1. Metabolism
    Carbohydrate   Energy   Lipid   Nucleotide   Amino acid   Other amino acid
    Glycan   PK/NRP   Cofactor/vitamin   Secondary metabolite   Xenobiotics
2. Genetic Information Processing
3. Environmental Information Processing
4. Cellular Processes
5. Human Diseases

and also on the structure relationships (KEGG drug structure maps) in:
6. Drug Development


1. Metabolism

1.1 Carbohydrate Metabolism
Glycolysis / Gluconeogenesis
Citrate cycle (TCA cycle)
Pentose phosphate pathway
Pentose and glucuronate interconversions
Fructose and mannose metabolism
Galactose metabolism
Ascorbate and aldarate metabolism
Starch and sucrose metabolism
Aminosugars metabolism
Nucleotide sugars metabolism
Pyruvate metabolism
Glyoxylate and dicarboxylate metabolism
Propanoate metabolism
Butanoate metabolism
C5-Branched dibasic acid metabolism
Inositol metabolism
Inositol phosphate metabolism
1.2 Energy Metabolism
Oxidative phosphorylation Revised!
ATP synthesis
Photosynthesis
Carbon fixation
Reductive carboxylate cycle (CO2 fixation)
Methane metabolism
Nitrogen metabolism
Sulfur metabolism
1.3 Lipid Metabolism
Fatty acid biosynthesis
Fatty acid elongation in mitochondria
Fatty acid metabolism
Synthesis and degradation of ketone bodies
Biosynthesis of steroids
Bile acid biosynthesis
C21-Steroid hormone metabolism
Androgen and estrogen metabolism
Glycerolipid metabolism
Glycerophospholipid metabolism
Sphingolipid metabolism
Arachidonic acid metabolism
Linoleic acid metabolism
1.4 Nucleotide Metabolism
Purine metabolism
Pyrimidine metabolism
1.5 Amino Acid Metabolism
Glutamate metabolism
Alanine and aspartate metabolism
Glycine, serine and threonine metabolism
Methionine metabolism
Cysteine metabolism
Valine, leucine and isoleucine degradation
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Lysine degradation
Arginine and proline metabolism
Histidine metabolism
Tyrosine metabolism
Phenylalanine metabolism
Tryptophan metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Urea cycle and metabolism of amino groups
1.6 Metabolism of Other Amino Acids
beta-Alanine metabolism
Taurine and hypotaurine metabolism
Aminophosphonate metabolism
Selenoamino acid metabolism
Cyanoamino acid metabolism
D-Glutamine and D-glutamate metabolism
D-Arginine and D-ornithine metabolism
D-Alanine metabolism
Glutathione metabolism
1.7 Glycan Biosynthesis and Metabolism
N-Glycan biosynthesis
High-mannose type N-glycan biosynthesis
N-Glycan degradation
O-Glycan biosynthesis
Chondroitin sulfate biosynthesis
Heparan sulfate biosynthesis
Keratan sulfate biosynthesis
Glycosaminoglycan degradation
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
Glycosphingolipid biosynthesis - lactoseries
Glycosphingolipid biosynthesis - neo-lactoseries
Glycosphingolipid biosynthesis - globoseries
Glycosphingolipid biosynthesis - ganglioseries
Glycan structures - biosynthesis 1
Glycan structures - biosynthesis 2
Glycan structures - degradation
1.8 Biosynthesis of Polyketides and Nonribosomal Peptides
Type I polyketide structures
Biosynthesis of 12-, 14- and 16-membered macrolides
Biosynthesis of ansamycins
Biosynthesis of type II polyketide backbone
Biosynthesis of type II polyketide products
Polyketide sugar unit biosynthesis
Nonribosomal peptide structures
Biosynthesis of siderophore group nonribosomal peptides
Biosynthesis of vancomycin group antibiotics
1.9 Metabolism of Cofactors and Vitamins
Thiamine metabolism
Riboflavin metabolism
Vitamin B6 metabolism
Nicotinate and nicotinamide metabolism
Pantothenate and CoA biosynthesis
Biotin metabolism
Folate biosynthesis
One carbon pool by folate
Retinol metabolism
Porphyrin and chlorophyll metabolism
Ubiquinone biosynthesis
1.10 Biosynthesis of Secondary Metabolites
Terpenoid biosynthesis
Diterpenoid biosynthesis
Monoterpenoid biosynthesis
Limonene and pinene degradation
Indole and ipecac alkaloid biosynthesis
Stilbene, coumarine and lignin biosynthesis
Flavonoid biosynthesis
Alkaloid biosynthesis I
Alkaloid biosynthesis II
Penicillins and cephalosporins biosynthesis
beta-Lactam resistance
Streptomycin biosynthesis
Tetracycline biosynthesis
Clavulanic acid biosynthesis
Puromycin biosynthesis
Novobiocin biosynthesis
1.11 Xenobiotics Biodegradation and Metabolism
Caprolactam degradation
Biphenyl degradation
Toluene and xylene degradation
gamma-Hexachlorocyclohexane degradation
3-Chloroacrylic acid degradation
1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) degradation
2,4-Dichlorobenzoate degradation
1,2-Dichloroethane degradation
Tetrachloroethene degradation
Styrene degradation
1,4-Dichlorobenzene degradation
Nitrobenzene degradation
Ethylbenzene degradation
Fluorene degradation
Carbazole degradation
Benzoate degradation via CoA ligation
Benzoate degradation via hydroxylation
Atrazine degradation
Bisphenol A degradation
1- and 2-Methylnaphthalene degradation
Metabolism of xenobiotics by cytochrome P450

2. Genetic Information Processing

2.1 Transcription
RNA biosynthesis (illustration)
2.2 Translation
Protein biosynthesis (illustration)
Aminoacyl-tRNA biosynthesis
2.3 Folding, Sorting and Degradation
2.4 Replication and Repair

3. Environmental Information Processing

3.1 Membrane Transport
3.2 Signal Transduction
3.3 Signaling Molecules and Interaction

4. Cellular Processes

4.1 Cell Motility
4.2 Cell Growth and Death
4.3 Cell Communication
4.4 Endocrine System
4.5 Immune System
4.6 Nervous System
4.7 Sensory System
4.8 Development
4.9 Behavior

5. Human Diseases

5.1 Neurodegenerative Disorders
5.2 Infectious Diseases
5.3 Metabolic Disorders

6. Drug Development

6.1 Chronology: Antibiotics
Penicillins
Cephalosporins - parenteral agents
Cephalosporins - oral agents
Aminoglycosides - Streptomyces
Aminoglycosides - Micromonospora
Tetracyclines
Macrolides and ketolides
Quinolones
Rifamycins
6.2 Chronology: Nervous System Agents
Hypnotics
Anxiolytics New!
Anticonvulsants
Local analgesic
Antipsychotics
Antipsychotics - phenothiazines
Antipsychotics - butyrophenones
Antidepressants
6.3 Chronology: Other Drugs
Azoles
Quinolines
Statins
Sulfonamide derivatives - sulfa drugs
Sulfonamide derivatives - diuretics
Sulfonamide derivatives - hypoglycemic agents
Eicosanoids
Prostaglandins
6.4 Target Based Structure Classification
Serotonin receptor agonists/antagonists
Dopamine receptor agonists/antagonists
Histamine receptor antagonists
beta-Adrenoceptor agonists/antagonists New!
alpha-Adrenoceptor agonists/antagonists New!
Calcium channel blocking agents New!
Catecholamine transferase inhibitors New!
Angiotensin antagonists
6.5 Skeleton Based Structure Classification
Benzoic acid family
2-Aminothiazole family
1,2-Diphenyl substitution family
Furan family
Naphthalene family
Sulfonamide family
Butyrophenone family
Benzodiazepine family

Last updated: July 19, 2006
KEGG GenomeNet Kanehisa Laboratories